Kavli Affiliate: Eric D. Siggia | Authors: Ismail Hajji, Eric D Siggia, Francis Corson and Wolfgang Keil | Summary: During development, cells gradually assume specialized fates via changes of transcriptional dynamics in thousands of genes. Terminal cell identities are then stabilized through the convergence of gene regulatory network dynamics and the accumulation of epigenetic DNA […]
Continue.. Quantitative guiding of developmental cell fate transitions using gene-free modelling