Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy

Posted by dbos Columbia, This Week: Neuroscience

Kavli Affiliate: Eric D. Siggia | Authors: Stefano Fusi and Liam Paninski | Summary: The brain is highly structured both at anatomical and functional levels. However, within individual brain areas, neurons often exhibit very diverse and seemingly disorganized responses. A more careful analysis shows that these neurons can sometimes be grouped together into specialized subpopulations […]


Continue.. Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy

Quantitative guiding of developmental cell fate transitions using gene-free modelling

Posted by dbos Rockefeller, This Week: Neuroscience

Kavli Affiliate: Eric D. Siggia | Authors: Ismail Hajji, Eric D Siggia, Francis Corson and Wolfgang Keil | Summary: During development, cells gradually assume specialized fates via changes of transcriptional dynamics in thousands of genes. Terminal cell identities are then stabilized through the convergence of gene regulatory network dynamics and the accumulation of epigenetic DNA […]


Continue.. Quantitative guiding of developmental cell fate transitions using gene-free modelling

Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits

Posted by dbos This Week: Neuroscience, UCSF

Kavli Affiliate: Adam Gazzaley | Authors: Lorenzo Pasquini, Jakub Vohryzek, Anira Escrichs, Yonatan Sanz Perl, Adrian Ponce-Alvarez, Sebastian Idesis, Manesh Girn, Leor Roseman, Jennifer M Mitchell, Adam Gazzaley, Morten Kringelbach, David J Nutt, Taylor Lyons, Robin L Carhart-Harris and Gustavo Deco | Summary: Psilocybin has been shown to induce fast and sustained improvements in mental […]


Continue.. Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits