Transgenerational transmission of post-zygotic mutations suggests symmetric contribution of first two blastomeres to human germline

Posted by dbos Yale

Kavli Affiliate: Flora Vaccarino | Authors: Yeongjun Jang, Livia Tomasini, Taejeong Bae, Anna Szekely, Flora M. Vaccarino and Alexej Abyzov | Summary: Little is known about the origin of germ cells in humans. We previously leveraged post-zygotic mutations to reconstruct zygote-rooted cell lineage ancestry trees in a phenotypically normal woman, termed NC0. Here, by sequencing […]


Continue.. Transgenerational transmission of post-zygotic mutations suggests symmetric contribution of first two blastomeres to human germline

The FRB-searching pipeline of the Tianlai Cylinder Pathfinder Array

Posted by Chicago

Kavli Affiliate: Albert Stebbins | First 5 Authors: Zijie Yu, Furen Deng, Shijie Sun, Chenhui Niu, Jixia Li | Summary: This paper presents the design, calibration, and survey strategy of the Fast Radio Burst (FRB) digital backend and its real-time data processing pipeline employed in the Tianlai Cylinder Pathfinder array. The array, consisting of three […]


Continue.. The FRB-searching pipeline of the Tianlai Cylinder Pathfinder Array

High-Efficiency Low-Noise Optomechanical Crystal Photon-Phonon Transducers

Posted by dbos Caltech

Kavli Affiliate: Oskar Painter | First 5 Authors: Sameer Sonar, Utku Hatipoglu, Srujan Meesala, David Lake, Hengjiang Ren | Summary: Optomechanical crystals (OMCs) enable coherent interactions between optical photons and microwave acoustic phonons, and represent a platform for implementing quantum transduction between microwave and optical signals. Optical absorption-induced thermal noise at cryogenic (millikelvin) temperatures is […]


Continue.. High-Efficiency Low-Noise Optomechanical Crystal Photon-Phonon Transducers

Functional photoacoustic noninvasive Doppler angiography in humans

Posted by dbos Caltech

Kavli Affiliate: Lihong V. Wang | First 5 Authors: Yang Zhang, Joshua Olick-Gibson, Karteekeya Sastry, Lihong V. Wang, | Summary: Optical imaging of blood flow yields critical functional insights into the circulatory system, but its clinical implementation has typically been limited to shallow depths (~1 millimeter) due to light scattering in biological tissue. Here, we […]


Continue.. Functional photoacoustic noninvasive Doppler angiography in humans