How low can you go? Short-read polishing of Oxford Nanopore bacterial genome assemblies

Posted by dbos UCSF

Kavli Affiliate: Robert Edwards | Authors: George Bouras, Louise M Judd, Robert A Edwards, Sarah Vreugde, Timothy P. Stinear and Ryan R Wick | Summary: It is now possible to assemble near-perfect bacterial genomes using Oxford Nanopore Technologies (ONT) long reads, but short-read polishing is still required for perfection. However, the effect of short-read depth […]


Continue.. How low can you go? Short-read polishing of Oxford Nanopore bacterial genome assemblies

Control of flow behavior in complex fluids using automatic differentiation

Posted by dbos Harvard

Kavli Affiliate: Michael Brenner | First 5 Authors: Mohammed Alhashim, Kaylie Hausknecht, Michael Brenner, , | Summary: Inverse design of complex flows is notoriously challenging because of the high cost of high dimensional optimization. Usually, optimization problems are either restricted to few control parameters, or adjoint-based approaches are used to convert the optimization problem into […]


Continue.. Control of flow behavior in complex fluids using automatic differentiation