Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing

Posted by klaurent Rockefeller

Kavli Affiliate: Robert B. Darnell | Authors: Leena Ali Ibrahim, Brie Wamsley, Norah Alghamdi, Nusrath Yusuf, Elaine Sevier, Ariel Hairston, Mia Sherer, Xavier Hubert Jaglin, Qing Xu, Lijua Gao, Alireza Khodadadi-Jamayran, Emilia Favuzzi, Yuan Yuan, Jordane Dimidschstein, Robert Darnell and Gordon Fishell | Summary: Somatostatin interneurons are the earliest born population of cortical inhibitory cells. […]


Continue.. Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing

Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria vector

Posted by klaurent Columbia

Kavli Affiliate: Scott Small | Authors: Scott T Small, Carlo Costantini, N’Fale Sagnon, Moussa W Guelbeogo, Scott J Emrich, Andrew D Kern, Michael C Fontaine and Nora J Besansky | Summary: Abstract Local adaptation results in the formation of ecotypes–conspecific groups with heritable differences that increase fitness to distinct environments. The adaptive significance of ecotypes […]


Continue.. Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria vector

The Clustered Gamma Protocadherin Pcdhγc4 Isoform Regulates Cortical Interneuron Programmed Cell Death in the Mouse Cortex

Posted by klaurent UCSF

Kavli Affiliate: Arturo Alvarez-Buylla, Andrea Hasenstaub, Michael Stryker | Authors: Walter R Mancia Leon, David M Steffen, Fiona Dale-Huang, Benjamin Rakela, Arnar Breevoort, Ricardo Romero-Rodriguez, Andrea R Hasenstaub, Michael P Stryker, Joshua A Weiner and Arturo Alvarez-Buylla | Summary: Cortical function critically depends on inhibitory/excitatory balance. Cortical inhibitory interneurons (cINs) are born in the ventral […]


Continue.. The Clustered Gamma Protocadherin Pcdhγc4 Isoform Regulates Cortical Interneuron Programmed Cell Death in the Mouse Cortex

Semantic-Guided Generative Image Augmentation Method with Diffusion Models for Image Classification

Posted by dbos Berkeley

Kavli Affiliate: Feng Wang | First 5 Authors: Bohan Li, Xiao Xu, Xinghao Wang, Yutai Hou, Yunlong Feng | Summary: Existing image augmentation methods consist of two categories: perturbation-based methods and generative methods. Perturbation-based methods apply pre-defined perturbations to augment an original image, but only locally vary the image, thus lacking image diversity. In contrast, […]


Continue.. Semantic-Guided Generative Image Augmentation Method with Diffusion Models for Image Classification

Semantic-Guided Generative Image Augmentation Method with Diffusion Models for Image Classification

Posted by klaurent Berkeley

Kavli Affiliate: Feng Wang | First 5 Authors: Bohan Li, Xiao Xu, Xinghao Wang, Yutai Hou, Yunlong Feng | Summary: Existing image augmentation methods consist of two categories: perturbation-based methods and generative methods. Perturbation-based methods apply pre-defined perturbations to augment an original image, but only locally vary the image, thus lacking image diversity. In contrast, […]


Continue.. Semantic-Guided Generative Image Augmentation Method with Diffusion Models for Image Classification

Smooth, homogeneous, high-purity Nb3Sn superconducting RF resonant cavity by seed-free electrochemical synthesis

Posted by dbos Cornell

Kavli Affiliate: David A. Muller | First 5 Authors: Zeming Sun, Zhaslan Baraissov, Ryan D. Porter, Liana Shpani, Yu-Tsun Shao | Summary: Workbench-size particle accelerators, enabled by Nb3Sn-based superconducting radio-frequency (SRF) cavities, hold the potential of driving scientific discovery by offering a widely accessible and affordable source of high-energy electrons and X-rays. Thin-film Nb3Sn RF […]


Continue.. Smooth, homogeneous, high-purity Nb3Sn superconducting RF resonant cavity by seed-free electrochemical synthesis

Construction of a 3D whole organism spatial atlas by joint modeling of multiple slices

Posted by klaurent UCSD / Salk

Kavli Affiliate: Angela Wu | Authors: Gefei Wang, Jia Zhao, Yan Yan, Yang Wang, Angela Ruohao Wu and Can Yang | Summary: Spatial transcriptomics (ST) technologies are revolutionizing the way that researchers explore the spatial architecture of tissues. Currently, ST data analysis is often restricted to 2D space within a single tissue slice, limiting our […]


Continue.. Construction of a 3D whole organism spatial atlas by joint modeling of multiple slices

Auditory memory of complex sounds in sparsely distributed, highly correlated neurons in the auditory cortex

Posted by klaurent Hopkins

Kavli Affiliate: Patrick Kanold | Authors: HiJee Kang and Patrick O Kanold | Summary: Listening in complex sound environments requires rapid segregation of different sound sources e.g., speakers from each other, speakers from other sounds, or different instruments in an orchestra, and also adjust auditory processing on the prevailing sound conditions. Thus, fast encoding of […]


Continue.. Auditory memory of complex sounds in sparsely distributed, highly correlated neurons in the auditory cortex

The double-drift illusion biases the marmoset oculomotor system

Posted by klaurent UCSD / Salk

Kavli Affiliate: John Reynolds | Authors: Nicholas M Dotson, Zachary W Davis, Jared M Salisbury, Stephanie E Palmer, Patrick Cavanagh and John Reynolds | Summary: Abstract The double-drift illusion has two unique characteristics: the error between the perceived and physical position of the stimulus grows over time, and saccades to the moving target land much […]


Continue.. The double-drift illusion biases the marmoset oculomotor system

Histone bivalency regulates the timing of cerebellar granule cell development

Posted by klaurent Rockefeller

Kavli Affiliate: Mary E. Hatten, C. David Allis | Authors: Kärt Mätlik, Eve-Ellen Govek, Matthew R. Paul, C. David Allis and Mary E. Hatten | Summary: Abstract Developing neurons undergo a progression of morphological and gene expression changes as they transition from neuronal progenitors to mature, multipolar neurons. Here we use RNA-seq and H3K4me3 and […]


Continue.. Histone bivalency regulates the timing of cerebellar granule cell development