Batch Effects are Causal Effects: Applications in Human Connectomics

Kavli Affiliate: Brian Caffo, Joshua Vogelstein | Authors: Eric W. Bridgeford, Michael Powell, Gregory Kiar, Stephanie Noble, Jaewon Chung, Sambit Panda, Ross Lawrence, Ting Xu, Michael Milham, Brian Caffo and Joshua T. Vogelstein | Summary: Batch effects, undesirable sources of variance across multiple experiments, present a substantial hurdle for scientific and clinical discoveries. Specifically, the […]


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A systematic search for RNA structural switches across the human transcriptome

Kavli Affiliate: Yifan Cheng | Authors: Matvei Khoroshkin, Daniel Asarnow, Albertas Navickas, Aidan Winters, Johnny Yu, Simon K. Zhou, Shaopu Zhou, Christina Palka, Lisa Fish, K. Mark Ansel, Yifan Cheng, Luke A. Gilbert and Hani Goodarzi | Summary: RNA structural switches are key regulators of gene expression in bacteria, yet their characterization in Metazoa remains […]


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Angular spectrum of quantum fluctuations in causal structure

Kavli Affiliate: Craig Hogan | First 5 Authors: Craig Hogan, Ohkyung Kwon, Nathaniel Selub, , | Summary: Scaling arguments are used to constrain the angular spectrum of distortions on boundaries of macroscopic causal diamonds, produced by Planck-scale vacuum fluctuations of causally-coherent quantum gravity. The small-angle spectrum of displacement is derived from a form of scale […]


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