Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions

Posted by klaurent Hopkins

Kavli Affiliate: Michael Beer | Authors: Renhe Luo, Jielin Yan, Jin Woo Oh, Wang Xi, Dustin Shigaki, Wilfred Wong, Hyunwoo Cho, Dylan Murphy, Ronald Cutler, Bess P. Rosen, Julian Pulecio, Dapeng Yang, Rachel Glenn, Tingxu Chen, Qing V. Li, Thomas Vierbuchen, Simone Sidoli, Effie Apostolou, Danwei Huangfu and Michael A. Beer | Summary: Comprehensive enhancer […]


Continue.. Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions

Cortico-Striatal Beta-Oscillations as a Marker of Learned Reward Value

Posted by klaurent UCSD / Salk

Kavli Affiliate: Dhakshin Ramanathan, Jyoti Mishra | Authors: M.F. Koloski, S. Hulyalkar, T. Tang, X. Wu, L. Fakhraei, S.A. Barnes, J. Mishra, D.S. Ramanathan | Summary: Abstract Single neuron correlates of reward value have been observed in brain regions along the cortico-striatal pathway including ventral striatum, orbital, and medial prefrontal cortex. Brain imaging studies in […]


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Active galactic nuclei feedback in an elliptical galaxy (III): the impacts and fate of cosmological inflow

Posted by klaurent Peking

Kavli Affiliate: Yingjie Peng | First 5 Authors: Bocheng Zhu, Feng Yuan, Suoqing Ji, Yingjie Peng, Luis C. Ho | Summary: The cosmological inflow of a galaxy is speculated to be able to enter the galaxy and enhance the star formation rate (SFR) and black hole accretion rate (BHAR). In this paper, by performing high-resolution […]


Continue.. Active galactic nuclei feedback in an elliptical galaxy (III): the impacts and fate of cosmological inflow

Design of an ultra-low mode volume piezo-optomechanical quantum transducer

Posted by klaurent Caltech

Kavli Affiliate: Oskar Painter | First 5 Authors: Piero Chiappina, Jash Banker, Srujan Meesala, David Lake, Steven Wood | Summary: Coherent transduction of quantum states from the microwave to the optical domain can play a key role in quantum networking and distributed quantum computing. We present the design of a piezo-optomechanical device formed in a […]


Continue.. Design of an ultra-low mode volume piezo-optomechanical quantum transducer