Membrane remodeling properties of the Parkinson’s disease protein LRRK2

Kavli Affiliate: Pietro DeCamilli | Authors: Xinbo Wang, Javier Espadas, Yumei Wu, Shujun Cai, Jinghua Ge, Lin Shao, Aurélien Roux and Pietro De Camilli | Summary: Mutations in Leucine-rich repeat kinase 2 (LRRK2) are responsible for late-onset autosomal dominant Parkinson’s disease (PD). LRRK2 has been implicated in a wide range of physiological processes including membrane […]


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Uncovering dark matter density profiles in dwarf galaxies with graph neural networks

Kavli Affiliate: Lina Necib | First 5 Authors: Tri Nguyen, Siddharth Mishra-Sharma, Reuel Williams, Lina Necib, | Summary: Dwarf galaxies are small, dark matter-dominated galaxies, some of which are embedded within the Milky Way. Their lack of baryonic matter (e.g., stars and gas) makes them perfect test beds for probing the properties of dark matter […]


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Extensions and approximations of Banach-valued Sobolev functions

Kavli Affiliate: Zheng Zhu | First 5 Authors: Miguel García-Bravo, Toni Ikonen, Zheng Zhu, , | Summary: In complete metric measure spaces equipped with a doubling measure and supporting a weak Poincar’e inequality, we investigate when a given Banach-valued Sobolev function defined on a subset satisfying a measure-density condition is the restriction of a Banach-valued […]


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On the formation of over-ionized plasma in evolved supernova remnants

Kavli Affiliate: Tadayuki Takahashi | First 5 Authors: Miho Katsuragawa, Shiu-Hang Lee, Hirokazu Odaka, Aya Bamba, Hideaki Matsumura | Summary: One of the outstanding mysteries surrounding the rich diversity found in supernova remnants (SNRs) is the recent discovery of over-ionized or recombining plasma from a number of dynamically evolved objects. To help decipher its formation […]


Continue.. On the formation of over-ionized plasma in evolved supernova remnants