Mouse models of SYNGAP1-related intellectual disability

Kavli Affiliate: Hey-Kyoung Lee, Richard Huganir | Authors: Yoichi Araki, Elizabeth E. Gerber, Kacey E. Rajkovich, Ingie Hong, Richard C. Johnson, Hey-Kyoung Lee, Alfredo Kirkwood and Richard L. Huganir | Summary: SYNGAP1 is a Ras-GTPase activating protein highly enriched at excitatory synapses in the brain. De novo loss-of-function mutations in SYNGAP1 are a major cause […]


Continue.. Mouse models of SYNGAP1-related intellectual disability

Contrasting synaptic roles of MDGA1 and MDGA2

Kavli Affiliate: Roger Nicoll | Authors: Michael A. Bemben, Matthew A. Sandoval, Aliza A. Le, Sehoon Won, Vivian N Chau, Julie C. Lauterborn, Salvatore Incontro, Kathy H. Li, Alma L. Burlingame, Katherine W. Roche, Christine M. Gall, Roger A. Nicoll and Javier Diaz-Alonso | Summary: Neurodevelopmental disorders are frequently linked to mutations in synaptic organizing […]


Continue.. Contrasting synaptic roles of MDGA1 and MDGA2

GC-Flow: A Graph-Based Flow Network for Effective Clustering

Kavli Affiliate: Xiang Zhang | First 5 Authors: Tianchun Wang, Farzaneh Mirzazadeh, Xiang Zhang, Jie Chen | Summary: Graph convolutional networks (GCNs) are emph{discriminative models} that directly model the class posterior $p(y|mathbf{x})$ for semi-supervised classification of graph data. While being effective, as a representation learning approach, the node representations extracted from a GCN often miss […]


Continue.. GC-Flow: A Graph-Based Flow Network for Effective Clustering

Cluster Cosmology Without Cluster Finding

Kavli Affiliate: Risa H. Wechsler | First 5 Authors: Enia Xhakaj, Alexie Leauthaud, Johannes Lange, Elisabeth Krause, Andrew Hearin | Summary: We propose that observations of super-massive galaxies contain cosmological constraining power similar to conventional cluster cosmology, and we provide promising indications that the associated systematic errors are comparably easier to control. We consider a […]


Continue.. Cluster Cosmology Without Cluster Finding

Extending the Computational Reach of a Superconducting Qutrit Processor

Kavli Affiliate: Irfan Siddiqi | First 5 Authors: Noah Goss, Samuele Ferracin, Akel Hashim, Arnaud Carignan-Dugas, John Mark Kreikebaum | Summary: Quantum computing with qudits is an emerging approach that exploits a larger, more-connected computational space, providing advantages for many applications, including quantum simulation and quantum error correction. Nonetheless, qudits are typically afflicted by more […]


Continue.. Extending the Computational Reach of a Superconducting Qutrit Processor

Extending the Computational Reach of a Superconducting Qutrit Processor

Kavli Affiliate: Irfan Siddiqi | First 5 Authors: Noah Goss, Samuele Ferracin, Akel Hashim, Arnaud Carignan-Dugas, John Mark Kreikebaum | Summary: Quantum computing with qudits is an emerging approach that exploits a larger, more-connected computational space, providing advantages for many applications, including quantum simulation and quantum error correction. Nonetheless, qudits are typically afflicted by more […]


Continue.. Extending the Computational Reach of a Superconducting Qutrit Processor

Roadmapping the Next Generation of Silicon Photonics

Kavli Affiliate: John E. Bowers | First 5 Authors: Sudip Shekhar, Wim Bogaerts, Lukas Chrostowski, John E. Bowers, Michael Hochberg | Summary: Silicon photonics has developed into a mainstream technology driven by advances in optical communications. The current generation has led to a proliferation of integrated photonic devices from thousands to millions – mainly in […]


Continue.. Roadmapping the Next Generation of Silicon Photonics