Kavli Affiliate: Devanand Manoli and Jeremy Willsey | Authors: Ruchira Sharma, Kristen M. Berendzen, Amanda Everitt, Belinda Wang, Gina Williams, Shuyu Wang, Kara Quine, Rose D. Larios, Kimberly L. P. Long, Nerissa Hoglen, Bibi Alika Sulaman, Marie C. Heath, Michael Sherman, Matthew Kinkel, Angela Cai, Denis Galo, Lizandro Chan Caamal, Nastacia L. Goodwin, Annaliese Beery, […]
Kavli Affiliate: Michael Stryker | Authors: Luciano Dyballa, Greg D Field, Michael P Stryker and Steven W Zucker | Summary: We have created “encoding manifolds” to reveal the overall responses of a brain area to a variety of stimuli. Encoding manifolds organize response properties globally: each point on an encoding manifold is a neuron, and […]
Kavli Affiliate: Loren Frank | Authors: Michael E. Coulter, Anna K. Gillespie, Joshua P Chu, Eric L. Denovellis, Trevor T.K. Nguyen, Daniel Liu, Katherine Wadhwani, Biabhav Sharma, Kevin Wang, Xinyi Deng, Uri Eden, Caleb Kemere and Loren M. Frank | Summary: Humans can remember specific events without acting on them and can influence which memories […]
Kavli Affiliate: Michael Stryker | Authors: Yoshimichi Sato, Yuandong Li, Yuya Kato, Atsushi Kanoke, Yujiao Jennifer Sun, Yasuo Nishijima, Ruikang K Wang, Michael Stryker, Hidenori Endo and Jialing Liu | Summary: Type 2 diabetes mellitus (T2DM) is associated with impaired leptomeningeal collateral compensation and poor stroke outcome. Neutrophils tethering and rolling on endothelium after stroke […]
Kavli Affiliate: Bjoern Schwer | Authors: Sarah Cohen, Laura Cheradame, Karishma Pratt, Sarah Collins, Ashlie Barillas, Annika Carlson, Vijay Ramani, Gaelle Legube, Saul Villeda, Dyche Mullins and Bjoern Schwer | Summary: Loss of genomic information due to the accumulation of somatic DNA damage has been implicated in aging and neurodegeneration. Somatic mutations in human neurons […]
Kavli Affiliate: Arnold R. Kriegstein | Authors: Beika Zhu, Andi Wangzhou, Diankun Yu, Tao Li, Rachael Schmidt, Stacy L. De Florencio, Lauren Chao, Yonatan Perez, Lea Tenenholz Grinberg, Salvatore Spina, Richard M Ransohoff, Arnold Kriegstein, William W Seeley, Tomasz J. Nowakowski and Xianhua Piao | Summary: Germline genetic architecture of Alzheimer’s disease (AD) indicates microglial […]
Kavli Affiliate: Edward Chang | Authors: Jeremy Saal, Ankit N. Khambhati, Edward F. Chang and Prasad Shirvalkar | Summary: Background Intracranial EEG (iEEG) is crucial for understanding brain function, but stimulation-induced noise complicates data interpretation. Traditional artifact detection methods require manual user input or struggle with noise variability, especially with limited labeled data. Objective We […]
Kavli Affiliate: Yifan Cheng | Authors: Mingliang Jin, Robert Seed, Tiffany Shing, Yifan Cheng and Stephen Nishimura | Summary: The multifunctional cytokine TGF-β is produced in a latent form (L-TGF-β) where a RGD containing homodimeric prodomain forms a “ring” encircling mature TGF-β shielding it from its receptors. Thus L-TGF-β must be activated to function, a […]
Kavli Affiliate: Zachary Knight | Authors: Heeun Jang, Alexis Behne Sharma, Usan Dan, Jasmine H. Wong, Zachary A. Knight and Jennifer L. Garrison | Summary: Chronic dehydration is a leading cause of morbidity for the elderly, but how aging alters the fluid homeostasis system is not well understood. Here, we used a combination of physiologic, […]
Kavli Affiliate: Devanand Manoli and Jeremy Willsey | Authors: Ruchira Sharma, Kristen M. Berendzen, Amanda Everitt, Belinda Wang, Gina Williams, Shuyu Wang, Kara Quine, Rose D. Larios, Kimberly L. P. Long, Nerissa Hoglen, Bibi Alika Sulaman, Marie C. Heath, Michael Sherman, Matthew Kinkel, Angela Cai, Denis Galo, Lizandro Chan Caamal, Nastacia L. Goodwin, Annaliese Beery, […]