Identity-stable multi-animal tracking using bidirectional segmentation with object-level memory

Kavli Affiliate: Devanand Manoli and Christoph Kirst | Authors: Shuyu Wang, Kara Quine, Audrey Jordan, Shreya Dasari, Devanand S. Manoli and Christoph Kirst | Summary: Tracking animal behavior in naturalistic settings is essential for understanding social dynamics and their neural underpinnings. Pose estimation methods can produce accurate keypoints using framewise inference. However, post hoc tracking […]


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High-Fidelity Neural Speech Reconstruction through an Efficient Acoustic-Linguistic Dual-Pathway Framework

Kavli Affiliate: Edward Chang | Authors: Jiawei Li, Chunxu Guo, Chao Zhang, Edward F Chang and Yuanning Li | Summary: Reconstructing speech from neural recordings is crucial for understanding speech coding and developing brain-computer interfaces (BCIs). However, existing methods trade off acoustic richness (pitch, prosody) for linguistic intelligibility (words, phonemes). To overcome this limitation, we […]


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Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate

Kavli Affiliate: Alex Pollen | Authors: Jingwen W Ding, Chang N Kim, Megan S Ostrowski, Yashodara Abeykoon, Bryan J Pavlovic, Jenelle L Wallace, Tomasz J Nowakowski and Alex A Pollen | Summary: Human cortical neurogenesis involves conserved and specialized developmental processes during a restricted window of prenatal development. Radial glia (RG) neural stem cells shape […]


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Allosteric Disordering of eIF2B Regulates the Integrated Stress Response

Kavli Affiliate: Peter Walter | Authors: Udit Dalwadi, Advait Subramanian, Aniliese Deal, Julia Conrad, Meera Venkatesh, Morgane Boone, Pascal Egea, Lingjie He, Nimit Jain, John D Lee, Yuwei Liu, Lucas Reineke, Kazuki Saito, Nathaniel Talledge, Hannah Toutkoushian, Maxence Le Vasseur, Francesca Zappa, Raoul de Groot, Diego Acosta-Alvear, Christopher Arthur, Jodi Nunnari, Mauro Costa-Mattioli, James Crawford, […]


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Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Kavli Affiliate: Robert Edwards | Authors: Rumi Habib, Ryan S. Roark, Hui Li, Andrew Jesse Connell, Michael P. Hogarty, Kshitij Wagh, Shuyi Wang, Lorie Marchitto, Ashwin N. Skelly, John W. Carey, Kirsten J. Sowers, Kasirajan Ayyanathan, Samantha J. Plante, Frederic Bibollet-Ruche, Younghoon Park, Colby J. Agostino, Ajay Singh, Christian L. Martella, Emily Lewis, Jinery Lora, […]


Continue.. Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Allosteric Disordering of eIF2B Regulates the Integrated Stress Response

Kavli Affiliate: Peter Walter | Authors: Udit Dalwadi, Advait Subramanian, Aniliese Deal, Julia Conrad, Meera Venkatesh, Morgane Boone, Pascal Egea, Lingjie He, Nimit Jain, John D Lee, Yuwei Liu, Lucas Reineke, Kazuki Saito, Nathaniel Talledge, Hannah Toutkoushian, Maxence Le Vasseur, Francesca Zappa, Raoul de Groot, Diego Acosta-Alvear, Christopher Arthur, Jodi Nunnari, Mauro Costa-Mattioli, James Crawford, […]


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Disruption of theta-timescale spiking impairs learning but spares hippocampal replay

Kavli Affiliate: Loren Frank | Authors: Abhilasha Joshi, Alison E. Comrie, Samuel Bray, Abhijith Mankili, Jennifer A. Guidera, Rhino Nevers, Xulu Sun, Emily Monroe, Viktor Kharazia, Ryan Ly, Daniela Astudillo Maya, Denisse Morales-Rodriguez, Jai Yu, Anna Kiseleva, Victor Perez and Loren M. Frank | Summary: The ability to rapidly learn and retrieve salient information about […]


Continue.. Disruption of theta-timescale spiking impairs learning but spares hippocampal replay

agtools: a software framework to manipulate assembly graphs

Kavli Affiliate: Robert Edwards | Authors: Vijini Mallawaarachchi, George Bouras, Ryan R. Wick, Susanna R. Grigson, Bhavya Papudeshi and Robert A. Edwards | Summary: Assembly graphs are a fundamental data structure used by genome and metagenome assemblers to represent sequences and their overlap information, facilitating the assembler to construct longer genomic fragments. Apart from their […]


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Adrenomedullin restores human cortical interneurons migration defects induced by hypoxia

Kavli Affiliate: Jeremy Willsey | Authors: Alyssa Puno, Wojciech M Michno, Li Li, Amanda Everitt, Kate McCluskey, Saw Htun, Dhriti Nagar, Jong Bin Choi, Yuqin Dai, Seyeon Park, Emily Gurwitz, Jeremy Willsey, Fikri Birey and Anca M Pasca | Summary: Extremely preterm birth (at < 28 postconceptional weeks) leads to brain injury and represents the […]


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Prefrontal gamma oscillations engage dynamic cell type-specific configurations to support flexible behavior

Kavli Affiliate: Vikaas Sohal | Authors: Aarron Justin Phensy, Lara Louise Hagopian, Caitriona M. Costello, Simon Haziza, Omkar Ghenand, Yanping Zhang, Mark J. Schnitzer and Vikaas Singh Sohal | Summary: Cognitive dysfunction in conditions such as schizophrenia involves disrupted communication between the prefrontal cortex (PFC) and mediodorsal thalamus (MD). Parvalbumin interneurons (PVI) are known to […]


Continue.. Prefrontal gamma oscillations engage dynamic cell type-specific configurations to support flexible behavior