Separable global and local beta burst dynamics in motor cortex of primates

Kavli Affiliate: Karunesh Ganguly | Authors: Preeya Khanna, behraz farrokhi, Hoseok Choi, Sandon Griffin, Ian Heimbuch, Lisa Novik, Katherina Thiesen, John H Morrison, Robert Morecraft and Karunesh Ganguly | Summary: Sensorimotor beta band oscillations are known to modulate during normal movement control and abnormal beta modulation is linked to pathological bradykinesia. However, the functional differences […]


Continue.. Separable global and local beta burst dynamics in motor cortex of primates

Synaptic vesicles that store monoamines and glutamate differ in protein composition.

Kavli Affiliate: Robert Edwards | Authors: Hrach Asmerian, Alexia J. Diaz, Hongfei Xu, Juan A Oses-Prieto, Jacob Alberts, Anna M. Sanetra, Barathan Gnanabharathi, Noah Carr, Alma L. Burlingame, Robert H. Edwards and Katlin Silm | Summary: Neuromodulators such as the monoamines are known to differ from classical neurotransmitters like glutamate in the time scale of […]


Continue.. Synaptic vesicles that store monoamines and glutamate differ in protein composition.

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Kavli Affiliate: Robert Edwards | Authors: Rumi Habib, Ryan S. Roark, Hui Li, Andrew Jesse Connell, Michael P. Hogarty, Kshitij Wagh, Shuyi Wang, Lorie Marchitto, Ashwin N. Skelly, John W. Carey, Kirsten J. Sowers, Kasirajan Ayyanathan, Samantha J. Plante, Frederic Bibollet-Ruche, Younghoon Park, Colby J. Agostino, Ajay Singh, Christian L. Martella, Emily Lewis, Jinery Lora, […]


Continue.. Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Dynamics of auditory word form encoding in human speech cortex

Kavli Affiliate: Edward Chang | Authors: Yizhen Zhang, Matthew K Leonard, Laura Gwilliams, Ilina Bhaya-Grossman and Edward F Chang | Summary: When we hear continuous speech, we perceive it as a series of discrete words, despite the lack of clear boundaries in the acoustic signal. The superior temporal gyrus (STG) encodes phonetic elements like consonants […]


Continue.. Dynamics of auditory word form encoding in human speech cortex

Towards individualized deep brain stimulation: A stereoencephalography-based workflow for unbiased neurostimulation target identification

Kavli Affiliate: Edward Chang | Authors: Jeremy Saal, Kelly Kadlec, Anusha B. Allawala, Lucille Johnston, Ryan Leriche, Ritwik Vatsyayan, Yiyuan Han, Audrey Kist, Tommaso Di Ianni, Heather E. Dawes, Edward F. Chang, A Moses Lee, Andrew D. Krystal, Khaled Moussawi, Prasad Shirvalkar and Kristin K. Sellers | Summary: Background: Deep-brain stimulation (DBS) is increasingly being […]


Continue.. Towards individualized deep brain stimulation: A stereoencephalography-based workflow for unbiased neurostimulation target identification

Hebb’s Vision: The Structural Underpinnings of Hebbian Assemblies

Kavli Affiliate: Reza Abbasi Asl | Authors: Julian A Wagner-Carena, Sai Kate, Trevor Riordan, Reza Abbasi-Asl, Joe Aman, Adam Amster, Agnes L Bodor, Derrick Brittain, JoAnn Buchanan, Michael A Buice, Daniel J Bumbarger, Forrest Collman, Nuno Macarico da Costa, Daniel J Denman, Saskia EJ de Vries, Emily Joyce, Dan Kapner, Chase W King, Josh D […]


Continue.. Hebb’s Vision: The Structural Underpinnings of Hebbian Assemblies

An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes

Kavli Affiliate: Edward Chang | Authors: Elisabetta Furlanis, Min Dai, Brenda Leyva Garcia, Josselyn Vergara, Ana Pereira, Kenneth Pelkey, Thien Tran, Bram L. Gorissen, Anna Vlacho, Ariel Hairston, Shuhan Huang, Deepanjali Dwivedi, Sarah Du, Sara Wills, Justin McMahon, Anthony T. Lee, Edward F. Chang, Taha Razzaq, Ahmed Qazi, Geoffrey Vargish, Xiaoqing Yuan, Adam Caccavano, Steven […]


Continue.. An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes

Survey of hippocampal responses to sound in naive mice reveals widespread activation by broadband noise onsets

Kavli Affiliate: Andrea Hasenstaub | Authors: James Bigelow, Toshiaki Suzuki, Yulang Wu, Ying Hu and Andrea R Hasenstaub | Summary: Recent studies suggest some hippocampal (HC) neurons respond to passively presented sounds in naive subjects, but the specificity and prevalence of these responses remain unclear. We used Neuropixels probes to record unit activity in HC […]


Continue.. Survey of hippocampal responses to sound in naive mice reveals widespread activation by broadband noise onsets

D3 dopamine receptors implicate a subtype of medium spiny neuron in the aversive effects of antipsychotic medications

Kavli Affiliate: Kevin Bender | Authors: Elinor Lewis, Jessie Muir, Ling C Li, Julianna Glienke, Sarah Warren Gooding, Kevin Bender, Christina Kim and Jennifer Whistler | Summary: Second generation antipsychotics (SGAs) are widely used clinical tools, yet they often cause negative side effects and take weeks to become effective, leading to poor patient compliance. The […]


Continue.. D3 dopamine receptors implicate a subtype of medium spiny neuron in the aversive effects of antipsychotic medications

Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

Kavli Affiliate: Seth Shipman Eiman Azim | Authors: Abdulkadir Ozkan, Hari K Padmanabhan, Seth Shipman, Eiman Azim, Priyanka Kumar, Cameron Sadegh, Nazli Basak and Jeffrey D Macklis | Summary: Corticospinal neurons (CSN) centrally degenerate in amyotrophic lateral sclerosis (ALS), along with spinal motor neurons, and loss of voluntary motor function in spinal cord injury (SCI) […]


Continue.. Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors