Kavli Affiliate: Takaki Komiyama | Authors: An Wu, Qiyu Chen, Bin Yu, Soyoung Chae, Zijing Tan, Assaf Ramot and Takaki Komiyama | Summary: During the execution of learned motor skills, the neural population in the layer 2/3 (L2/3) of the primary motor cortex (M1) expresses a reproducible spatiotemporal activity pattern. It is debated whether M1 […]

Kavli Affiliate: Terrence Sejnowski | Authors: Thomas M Bartol, Mariam Ordyan, Terrence J Sejnowski, Padmini Rangamani and Mary B Kennedy | Summary: Long-term potentiation (LTP) is a biochemical process that underlies learning in excitatory glutamatergic synapses in the Central Nervous System (CNS). The critical early driver of LTP is autophosphorylation of the abundant postsynaptic enzyme, […]

Kavli Affiliate: Eiman Azim | Authors: Jake Lustig, Alexander Lammers, Julia Kaiser, Payal Patel, Aidan Raghu, James M. Conner, Phong Nguyen, Eiman Azim and Vibhu Sahni | Summary: The corticospinal tract (CST) facilitates skilled, precise movements, which necessitates that subcerebral projection neurons (SCPN) establish segmentally specific connectivity with brainstem and spinal circuits. Developmental molecular delineation […]

Kavli Affiliate: Yishi Jin | Authors: Erin M Ritchie, Siming Zhong, Qianyi Pu, Yunbo Li, Binhai Zheng and Yishi Jin | Summary: The conserved MAP3K12/Dual Leucine Zipper Kinase (DLK) plays versatile roles in neuronal development, axon injury and stress responses, and neurodegeneration, depending on cell-type and cellular contexts. Emerging evidence implicates abnormal DLK signaling in […]

Kavli Affiliate: Deanna J. Greene and Jeremy Willsey | Authors: Shefali S. Rai, Kate J. Godfrey, Kirk Graff, Ryann Tansey, Daria Merrikh, Shelly Yin, Matthew Feigelis, Damion V. Demeter, Tamara Vanderwal, Deanna J. Greene and Signe L. Bray | Summary: functional connectivity (FC) measurements are important for robust and reproducible findings, yet pediatric functional magnetic […]

Kavli Affiliate: Cory Miller | Authors: Vikram Pal Singh, Jingwen Li, Jude Mitchell and Cory Miller | Summary: Our understanding of how vision functions as primates actively navigate the real-world is remarkably sparse. As most data have been limited to chaired and typically head-restrained animals, the synergistic interactions of different motor actions/plans inherent to active […]

Kavli Affiliate: Massimo Scanziani | Authors: Guy Bouvier, Alessandro Sanzeni, Elizabeth Hamada, Nicolas Brunel and Massimo Scanziani | Summary: Head movements are sensed by the vestibular organs. Unlike classical senses, signals from vestibular organs are not conveyed to a dedicated cortical area but are broadcast throughout the cortex. Surprisingly, the routes taken by vestibular signals […]

Kavli Affiliate: Gabriel Silva | Authors: Jeziel D Damasceno, Gabriel LA Silva, Catarina A Marques, Marija Krasilnikova, Craig Lapsley, Dario Beraldi and Richard McCulloch | Summary: Understanding genome duplication requires characterisation of the locations where DNA replication initiates, termed origins. Genome-wide mapping of DNA replication origins has mainly been derived from population-based techniques, with only […]

Kavli Affiliate: Mark Ellisman | Authors: Francisco Joaquín Tassara, Mariano Barella, Lourdes Simó, Mailen Folgueira, Micaela Rodríguez-Caron, Juan Ignacio Ispizua, Mark H. Ellisman, Horacio O. de la Iglesia, M. Fernanda Ceriani and Julián Gargiulo | Summary: In vivo imaging of dynamic sub-cellular brain structures in Drosophila melanogaster is key to understanding several phenomena in neuroscience. […]