Multiple and subject-specific roles of uncertainty in reward-guided decision-making

Kavli Affiliate: Angela Yu | Authors: Alexander Paunov, Maëva L’Hôtellier, Zoe He, Dalin Guo, Angela Yu and Florent Meyniel | Summary: Decision-making in noisy, changing, and partially observable environments entails a basic tradeoff between immediate reward and longer-term information gain, known as the exploration-exploitation dilemma. Computationally, an effective way to balance this tradeoff is by […]


Continue.. Multiple and subject-specific roles of uncertainty in reward-guided decision-making

Neuromodulators generate multiple context-relevant behaviors in a recurrent neural network by shifting activity flows in hyperchannels

Kavli Affiliate: Kay Tye and Terrence Sejnowski | Authors: Ben Tsuda, Stefan C Pate, Kay M Tye, Hava T Siegelmann and Terrence J Sejnowski | Summary: Neuromodulators are critical controllers of neural states, with dysfunctions linked to various neuropsychiatric disorders. Although many biological aspects of neuromodulation have been studied, the computational principles underlying how neuromodulation […]


Continue.. Neuromodulators generate multiple context-relevant behaviors in a recurrent neural network by shifting activity flows in hyperchannels

State of India’s Birds 2023: A framework to leverage semi-structured citizen science for bird conservation

Kavli Affiliate: V. S. Ramachandran | Authors: Ashwin Viswanathan, Karthik Thrikkadeeri, Pradeep Koulgi, Praveen J, Arpit Deomurari, Ashish Jha, Ashwin Warudkar, Kulbhushansingh Suryawanshi, MD Madhusudan, Monica Kaushik, Naman Goyal, Priti bangal, Rajah Jayapal, Suhel Quader, Sutirtha Dutta, Tarun Menon and Vivek Ramachandran | Summary: Birds and their habitats are threatened with extinction around the world. […]


Continue.. State of India’s Birds 2023: A framework to leverage semi-structured citizen science for bird conservation

Evolution of lateralized gustation in nematodes

Kavli Affiliate: Sreekanth Chalasani | Authors: Marisa Mackie, Vivian Vy Le, Heather R Carstensen, Nicole R Kushnir, Dylan L Castro, Ivan M Dimov, Kathleen T Quach, Steve J Cook, Oliver Hobert, Sreekanth H Chalasani and Ray L Hong | Summary: Animals with small nervous systems have a limited number of sensory neurons that must encode […]


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The applicability of Regional Red List assessments for soil invertebrates: First assessment of five native earthworm species in Canada

Kavli Affiliate: John Reynolds | Authors: Helen R P Phillips, George Gardner Brown, Sam W. James, Jérôme Mathieu, John Warren Reynolds, Maheshi E Dharmasiri, Claire L. Singer, Maria J. I. Briones, Heather C. Procter and Erin K. Cameron | Summary: Summary: Earthworms (Annelida: Clitellata: Crassiclitellata) are prominent members of the soil community, important to many […]


Continue.. The applicability of Regional Red List assessments for soil invertebrates: First assessment of five native earthworm species in Canada

Intermittent Theta Burst Stimulation Drives Bi-Directional Changes in Excitability in Prefrontal Cortex

Kavli Affiliate: Jyoti Mishra and Dhakshin Ramanathan | Authors: Morteza Salimi, Milad Nazari, Jonathan Mishler, Jyoti Mishra and Dhakshin Ramanathan | Summary: Summary: Theta burst stimulation (TBS), an FDA-cleared treatment for depression, is hypothesized to modulate excitability in the prefrontal cortex, though this has not definitively been shown in vivo. We performed calcium imaging on […]


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Human rod photoreceptor outer segments are supported by accessory inner segment structures

Kavli Affiliate: Mark Ellisman | Authors: Tylor R Lewis, Natalia V Klementieva, Sebastien Phan, Carson M Castillo, Keun-Young Kim, Lauren Y Cao, Mark Ellisman, Vadim Y Arshavsky and Oleg Alekseev | Summary: The first steps in vision take place in photoreceptor cells, which are highly compartmentalized neurons exhibiting significant structural variation across species. The light-sensitive […]


Continue.. Human rod photoreceptor outer segments are supported by accessory inner segment structures

ER-phagy drives age-onset remodeling of endoplasmic reticulum structure-function and lifespan

Kavli Affiliate: Mark Ellisman | Authors: Eric KF Donahue, Nathaniel L Hepowit, Brennen Keuchel, Alexandra G Mulligan, Derek J Johnson, Mark Ellisman, Rafael Arrojo e Drigo, Jason A MacGurn and Kristopher Burkewitz | Summary: The endoplasmic reticulum (ER) comprises an array of structurally distinct subdomains, each with characteristic functions. While altered ER-associated processes are linked […]


Continue.. ER-phagy drives age-onset remodeling of endoplasmic reticulum structure-function and lifespan

Using phylogenetic summary statistics for epidemiological inference

Kavli Affiliate: Rafael Nunez | Authors: Rafael C Nunez, Gregory R Hart, Michael Famulare, Christopher Lorton and Joshua T Herbeck | Summary: Since the coining of the term phylodynamics, the use of phylogenies to understand infectious disease dynamics has steadily increased. As methods for phylodynamics and genomic epidemiology have proliferated and grown more computationally expensive, […]


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Synaptic Potentiation of Engram cells is Necessary and Sufficient for Context Fear Memory

Kavli Affiliate: Mark Mayford | Authors: Leonardo M Cardozo, Andre F Sousa, Blythe C Dillingham, Westley Dang, Nicholas Job, Eun J Yoo, Sural K Ranamukhaarachchi, Qi Yuan and Mark Mayford | Summary: The nature and distribution of the synaptic changes that underlie memory are not well understood. We examined the synaptic plasticity behind context fear […]


Continue.. Synaptic Potentiation of Engram cells is Necessary and Sufficient for Context Fear Memory