A Rational Information Gathering Account of Infant Habituation

Kavli Affiliate: Marcelo Mattar | Authors: Gili Karni, Marcelo Mattar, Lauren Emberson and Nathaniel Douglass Daw | Summary: Gaze is one of the primary experimental measures for studying cognitive development, especially in preverbal infants. However, the field is only beginning to develop a principled explanatory framework for making sense of the various factors affecting gaze. […]


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Complementary cortical and thalamic contributions to cell-type-specific striatal activity dynamics during movement

Kavli Affiliate: Takaki Komiyama | Authors: Enida Gjoni, Ram Dyuthi Sristi, Haixin Liu, Shahar Dror, Xinlei Lin, Keelin O’Neil, Oscar M Arroyo, Sun Woo Hong, Hannah Kim, Jeffrey Liu, Sonja Blumenstock, Byungkook Lim, Gal Mishne and Takaki Komiyama | Summary: Coordinated motor behavior emerges from information flow across brain regions. How long-range inputs drive cell-type-specific […]


Continue.. Complementary cortical and thalamic contributions to cell-type-specific striatal activity dynamics during movement

Pak, a downstream gene of ecdysone signaling, determines left-right polarity in the Drosophila brain through neuronal cell chirality

Kavli Affiliate: Ann-Shyn Chiang | Authors: So Sakamura, Komomo Suyama, Akari Tsujita, Fu-yu Hsu, Atsushi Tamada, Tomoyuki Miyashita, Minoru Saitoe, Ann-Shyn Chiang, Mikiko Inaki and Kenji Matsuno | Summary: Left-right (LR) asymmetry is a conserved characteristic of the brain in various animals and is related to its higher-order functions. The Drosophila brain has an LR […]


Continue.. Pak, a downstream gene of ecdysone signaling, determines left-right polarity in the Drosophila brain through neuronal cell chirality

Inhibitory neurons marked by the connectivity molecule Kirrel3 regulate memory precision

Kavli Affiliate: Mark Ellisman | Authors: Arnulfo B.N. Tunon-Ortiz, Dimitri Trankner, Chandler M. Peterson, Omar Shennib, Fangfei Ye, Jiani Shi, Sarah N. Brockway, Olivia Katherine Raines, Abbey Mahnke, Matthew Grega, Keun-Young Kim, Mark Ellisman, James G. Heys, Moriel Zelikowsky and Megan E Williams | Summary: The homophilic adhesion molecule Kirrel3 drives synapse formation between dentate […]


Continue.. Inhibitory neurons marked by the connectivity molecule Kirrel3 regulate memory precision

Small siphophage binding to an open state of the LptDE outer membrane lipopolysaccharide translocon

Kavli Affiliate: Robert E. Clark | Authors: Bert van den Berg, Emily Dunbar, Robert Clark, Arnaud Basle, Shenaz Allyjaun, Hector Newman, Julia Hubbard and Syma Khalid | Summary: Bacteriophages are bacterial viruses that provide alternatives to small-molecule drugs to combat infections by antibiotic-resistant bacteria. To infect a bacterial host, a phage needs to bind to […]


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Ecological Factors Affecting Prosociality in Marmoset Monkeys

Kavli Affiliate: Cory Miller | Authors: Anand R Mysorekar, Anushka Vispute and Cory Miller | Summary: Prosocial behaviors, such as cooperation and food sharing, are critical for maintaining group cohesion in social species, yet the influence of transient physiological states on these behaviors remains poorly understood. This study investigates how short-term ecological factors impact social […]


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Interpretable abstractions of artificial neural networks predict behavior and neural activity during human information gathering

Kavli Affiliate: Marcelo Mattar | Authors: Simone D’Ambrogio, Jan Grohn, Nima Khalighinejad, Marcelo Mattar, Laurence T Hunt and Matthew F Rushworth | Summary: It has been suggested that humans and other animals are driven by a fundamental desire to acquire information about opportunities available in their environments. Not only might such a desire explain pathological […]


Continue.. Interpretable abstractions of artificial neural networks predict behavior and neural activity during human information gathering

Immunoinformatics Approach to Engineer a Multi-Epitope Vaccine Against SdrG in Skin Commensal Staphylococcus epidermidis

Kavli Affiliate: Gabriel Silva | Authors: Shahina Akter, Gabriel Vinícius Rolim Silva, Jonas Ivan Nobre Oliveira, Umberto Laino Fulco, Xianyang Xu and Yu Vincent Fu | Summary: The human skin serves as a dynamic ecosystem for beneficial commensal bacteria such as Staphylococcus epidermidis, which play a crucial role in maintaining skin barrier integrity and modulating […]


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Deep Learning Improves Parameter Estimation in Reinforcement Learning Models

Kavli Affiliate: Marcelo Mattar | Authors: Hua-Dong Xiong, Li Ji-An, Marcelo G Mattar and Robert C Wilson | Summary: Cognitive modeling in psychology and neuroscience provides a formal approach to formulate and test hypotheses of cognitive processes. Such models rely on cognitive parameters that are intended to represent interpretable and identifiable psychological constructs. However, accurately […]


Continue.. Deep Learning Improves Parameter Estimation in Reinforcement Learning Models

Deep Learning Improves Parameter Estimation in Reinforcement Learning Models

Kavli Affiliate: Marcelo Mattar | Authors: Hua-Dong Xiong, Li Ji-An, Marcelo G Mattar and Robert C Wilson | Summary: Cognitive modeling in psychology and neuroscience provides a formal approach to formulate and test hypotheses of cognitive processes. Such models rely on cognitive parameters that are intended to represent interpretable and identifiable psychological constructs. However, accurately […]


Continue.. Deep Learning Improves Parameter Estimation in Reinforcement Learning Models