Open-source Photobleacher for Fluorescent Imaging of Large Pigment-Rich Tissues

Kavli Affiliate: Nathaniel Heintz | Authors: Tatsuya C. Murakami, Nick Belenko, Griffin Dennis, Cuidong Wang, Maria Esterlita Siantoputri, Yurie Maeda, Christina Pressl and Nathaniel Heintz | Summary: Fluorescent imaging enables visualization of the specific molecules of interest with high contrast, and the use of multiple fluorophores in a single tissue sample allows visualization of complex […]


Continue.. Open-source Photobleacher for Fluorescent Imaging of Large Pigment-Rich Tissues

TUCL-Seq for miRNA single molecule sequencing

Kavli Affiliate: Li Zhao | Authors: Jicai Fan, Zhao Li, Xuejiao You, Lei Liu, Huan Jin, Ping Wu, Yushan Han, Lei Sun, Pengwei Xu, Yongfeng Liu, Jianjun Luo and Qin Yan | Summary: MicroRNAs (miRNAs) are pivotal regulatory molecules in gene expression, and their precise quantification is essential for elucidating their roles in diverse biological […]


Continue.. TUCL-Seq for miRNA single molecule sequencing

Aging-dependent dysregulation of EXOSC2 is maintained in cancer as a dependency

Kavli Affiliate: Robert B. Darnell | Authors: Maria Skamagki, Cheng Zhang, Ezgi Hacisuleyman, Giuseppe Galleti, Chao Wu, Rajasekhar K Vinagolu, HyoKyeong Cha, Deniz Ata, Jongjin Kim, Taylor Weiskittel, Mame Diop, Thiri Aung, Michael Del Latto, Amanda S. Kim, Zhuoning Li, Matthew Miele, Rui Zhao, Laura H. Tang, Ronald C. Hendrickson, Paul B. Romesser, Jesse Joshua […]


Continue.. Aging-dependent dysregulation of EXOSC2 is maintained in cancer as a dependency

Suite3D: Volumetric cell detection for two-photon microscopy

Kavli Affiliate: Alipasha Vaziri | Authors: Ali Haydaroğlu, Sam Dodgson, Michael Krumin, Andrew Landau, Liad J. Baruchin, Tinya Chang, Jingkun Guo, David Meyer, Charu B. Reddy, Jian Zhong, Na Ji, Sylvia Schröder, Kenneth D. Harris, Alipasha Vaziri and Matteo Carandini | Summary: In two-photon imaging of neuronal activity it is common to acquire 3-dimensional volumes. […]


Continue.. Suite3D: Volumetric cell detection for two-photon microscopy

Haplotype-resolved reference genomes of the sea turtle clade unveil ultra-syntenic genomes with hotspots of divergence

Kavli Affiliate: Erich Jarvis | Authors: Larissa S. Arantes, Tom Brown, Diego De Panis, Scott D. Whiting, Erin L. LaCasella, Gabriella A. Carvajal, Adam Kennedy, Deana Edmunds, Blair P. Bentley, Jennifer Balacco, Conor Whelan, Nivesh Jain, Tatiana Tilley, Brian O’Toole, Patrick Traore, Erich D. Jarvis, Oliver Berry, Peter H. Dutton, Lisa M. Komoroske and Camila […]


Continue.. Haplotype-resolved reference genomes of the sea turtle clade unveil ultra-syntenic genomes with hotspots of divergence

Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant (Ooceraea biroi)

Kavli Affiliate: Daniel Kronauer | Authors: Kip D Lacy, Jina Lee, Kathryn Rozen-Gagnon, Wei Wang, Thomas S Carroll and Daniel J C Kronauer | Summary: Sex determination is a developmental switch that triggers sex-specific developmental programs. This switch is flipped by the expression of genes that promote male- or female-specific development. Many lineages have evolved […]


Continue.. Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant (Ooceraea biroi)

Neural representation of action symbols in primate frontal cortex

Kavli Affiliate: Winrich Freiwald | Authors: Lucas Y Tian, Kedar U Garzón, Adam G Rouse, Mark AG Eldridge, Marc H Schieber, Xiao-Jing Wang, Joshua B Tenenbaum and Winrich A Freiwald | Summary: At the core of intelligence is proficiency in solving new problems, including those that differ dramatically from problems seen before. Problem-solving, in turn, […]


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A distinctive subset of microglia positioned at the paraventricular zone are dedicated to cleaning the cerebrospinal fluid

Kavli Affiliate: Li Zhao | Authors: Guoyang Zhou, Jian He, Baojie Mao, Guo Cheng, Rui Zhang, Qiang Wang, Xiaoli Liu, Jiaxin Zheng, Ming Wang, Li Zhao, Peng Shi, Xiao Z Shen and Shu Wan | Summary: The interconnected ventricles in the central nervous system are filled with cerebrospinal fluid (CSF) which serves multifaceted roles including […]


Continue.. A distinctive subset of microglia positioned at the paraventricular zone are dedicated to cleaning the cerebrospinal fluid

Mosquito Cell Atlas: A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito

Kavli Affiliate: Leslie B. Vosshall | Authors: Olivia V. Goldman, Alexandra E. DeFoe, Yanyan Qi, Yaoyu Jiao, Shih-Che Weng, Leah Houri-Zeevi, Priyanka Lakhiani, Takeshi Morita, Jacopo Razzauti, Adriana Rosas-Villegas, Yael N. Tsitohay, Madison M. Walker, Ben R. Hopkins, Mosquito Cell Atlas Consortium, Omar S. Akbari, Laura B. Duvall, Helen White-Cooper, Trevor R. Sorrells, Roshan Sharma, […]


Continue.. Mosquito Cell Atlas: A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito

A vector-based strategy for olfactory navigation in Drosophila

Kavli Affiliate: Vanessa Ruta | Authors: Andrew F. Siliciano, Sun Minni, Chad Morton, Charles K. Dowell, Noelle B. Eghbali, Juliana Y. Rhee, L. F. Abbott and Vanessa Ruta | Summary: Odors serve as essential cues for navigation. Although tracking an odor plume has been modeled as a reflexive process, it remains unclear whether animals can […]


Continue.. A vector-based strategy for olfactory navigation in Drosophila