A vector-based strategy for olfactory navigation in Drosophila

Kavli Affiliate: Vanessa Ruta | Authors: Andrew F. Siliciano, Sun Minni, Chad Morton, Charles K. Dowell, Noelle B. Eghbali, Juliana Y. Rhee, L. F. Abbott and Vanessa Ruta | Summary: Odors serve as essential cues for navigation. Although tracking an odor plume has been modeled as a reflexive process, it remains unclear whether animals can […]


Continue.. A vector-based strategy for olfactory navigation in Drosophila

Evaluation of sequencing reads at scale using rdeval

Kavli Affiliate: Erich Jarvis | Authors: Giulio Formenti, Bonhwang Koo, Marco Sollitto, Jennifer Balacco, Nadolina Brajuka, Richard Burhans, Erick Duarte, Alice Maria Giani, Kirsty McCaffrey, Jack A Medico, Eugene W Myers, Patrik Smeds, Anton Nekrutenko and Erich D Jarvis | Summary: Motivation: Large sequencing data sets are produced and deposited into public archives at unprecedented […]


Continue.. Evaluation of sequencing reads at scale using rdeval

Optogenetic interrogation of the lateral-line sensory system reveals mechanisms of pattern separation in the zebrafish brain

Kavli Affiliate: A. James Hudspeth | Authors: Nicolas Velez, Sihao Lu, Brian Fabella, Caleb C. Reagor, Holland R Brown, Yuriria Vazquez, Adrian Jacobo and Albert James Hudspeth | Summary: The ability of animals to interact with their environment hinges on the brain’s capacity to distinguish between patterns of sensory information and accurately attribute them to […]


Continue.. Optogenetic interrogation of the lateral-line sensory system reveals mechanisms of pattern separation in the zebrafish brain

The conserved N-terminal SANT1-binding domain (SBD) of EZH2 Regulates PRC2 Activity

Kavli Affiliate: C. David Allis | Authors: Agata Lemiesz Patriotis, Yadira Soto-Feliciano, Douglas Barrows, Laiba Khan, Marylene Leboeuf, Peder Lund, Matthew R Marunde, Annaelle Djomo, Michael-Christopher Keogh, Thomas Carroll, Benjamin Garcia, Alexey A Soshnev and C. David Allis | Summary: Polycomb group proteins maintain gene expression patterns established during early development, with Polycomb Repressive Complex […]


Continue.. The conserved N-terminal SANT1-binding domain (SBD) of EZH2 Regulates PRC2 Activity

Evaluation of sequencing reads at scale using rdeval

Kavli Affiliate: Erich Jarvis | Authors: Giulio Formenti, Bonhwang Koo, Marco Sollitto, Jennifer Balacco, Nadolina Brajuka, Richard Burhans, Erick Duarte, Alice Maria Giani, Kirsty McCaffrey, Jack A Medico, Eugene W Myers and Erich D Jarvis | Summary: Motivation Large sequencing data sets are produced and deposited into public archives at unprecedented rates. The availability of […]


Continue.. Evaluation of sequencing reads at scale using rdeval

Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant

Kavli Affiliate: Daniel Kronauer | Authors: Kip D Lacy, Jina Lee, Kathryn Rozen-Gagnon, Wei Wang, Thomas S Carroll and Daniel J C Kronauer | Summary: Sex determination is a developmental switch that triggers sex-specific developmental programs. This switch is “flipped” by the expression of genes that promote male- or female-specific development. Many lineages have evolved […]


Continue.. Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant

Evolution of chronic lymphocytic leukemia after allogeneic stem cell transplant

Kavli Affiliate: Li Zhao | Authors: Haven R Garber, Danwei Wang, Celine Kerros, Hannah C Beird, Xizeng Mao, Nina G Howard, Jianhua Zhang, Jason Roszik, John P Miller, Paul Leonard, Yu Cao, Li Zhao, Xingzhi Song, Sahil Seth, Pei Lin, Huandong Sun, Lisa S St John, Sijie Lu, William Wierda, Issa F Khouri, Karen Clise-Dwyer, […]


Continue.. Evolution of chronic lymphocytic leukemia after allogeneic stem cell transplant

Whole-brain neural substrates of behavioral variability in the larval zebrafish

Kavli Affiliate: Alipasha Vaziri | Authors: Jason Manley and Alipasha Vaziri | Summary: Animals engaged in naturalistic behavior can exhibit a large degree of behavioral variability even under sensory invariant conditions. Such behavioral variability can include not only variations of the same behavior, but also variability across qualitatively different behaviors driven by divergent cognitive states, […]


Continue.. Whole-brain neural substrates of behavioral variability in the larval zebrafish

Opto-CLIP reveals dynamic FMRP regulation of mRNAs upon CA1 neuronal activation

Kavli Affiliate: Robert B. Darnell and Nathaniel Heintz | Authors: Ruth A Singer, Veronika Rajchin, Kwanghoon Park, Nathaniel Heintz and Robert B Darnell | Summary: Neuronal diversity and function are intricately linked to the dynamic regulation of RNA metabolism, including splicing, localization, and translation. Electrophysiologic studies of synaptic plasticity, models for learning and memory, are […]


Continue.. Opto-CLIP reveals dynamic FMRP regulation of mRNAs upon CA1 neuronal activation

Convergence of autism proteins at the cilium

Kavli Affiliate: Jeremy Willsey | Authors: Elina Kostyanovskaya, Micaela C. Lasser, Belinda Wang, James Schmidt, Ethel Bader, Chad Buteo, Juan Arbelaez, Aria Rani Sindledecker, Kate E. McCluskey, Octavio Castillo, Sheng Wang, Jeanselle Dea, Kathryn A. Helde, J. Michael Graglia, Elise Brimble, David B. Kastner, Aliza T. Ehrlich, Matthew W. State, A. Jeremy Willsey and Helen […]


Continue.. Convergence of autism proteins at the cilium