Kavli Affiliate: Keri Martinowich | Authors: Svitlana V Bach, Allison J Bauman, Darya Hosein, Jennifer J Tuscher, Lara Ianov, Kelsey M Greathouse, Benjamin W Henderson, Jeremy H. Herskowitz, Keri Martinowich and Jeremy J Day | Summary: Brain-derived neurotrophic factor (Bdnf) plays a critical role in brain development, dendritic growth, synaptic plasticity, as well as learning […]
Kavli Affiliate: Terrence Sejnowski | Authors: Yusi Chen, Huanqiu Zhang and Terrence J Sejnowski | Summary: We linked the temporal precision of neural encoding to the implementation of cognitive functions through predictive sequence learning. The hippocampus of rodents receives sequences of sensory inputs from the cortex during exploration and then encodes the sequences with millisecond […]
Kavli Affiliate: Li Zhao | Authors: Michelle Baker, Xibin Zhang, Alexandre Maciel-Guerra, Kubra Babaarslan, Yinping Dong, Wei Wang, Yujie Hu, David Renney, Longhai Liu, Hui Li, Zhiqin Tong, Nicole Pearcy, Meimei Zhang, Yingzhi Geng, Li Zhao, Zhihui Hao, Junshi Chen, Zixin Peng, Fengqin Li and Tania Dottorini | Summary: Sharing among different pathogens and commensals […]
Kavli Affiliate: Erich Jarvis | Authors: Anoushka Joglekar, Wen Hu, Bei Zhang, Oleksandr Narykov, Mark Diekhans, Jennifer Balacco, Lishomwa Ndhlovu, Teresa A Milner, Olivier Fedrigo, Erich D Jarvis, Gloria M Sheynkman, Dmitry Korkin, Margaret Elizabeth Ross and Hagen U Tilgner | Summary: RNA isoforms influence cell identity and function. Until recently, technological limitations prevented a […]
Kavli Affiliate: Liam Paninski, Nathaniel Sawtell | Authors: Dan Biderman, Matthew R Whiteway, Cole Hurwitz, Nicholas R Greenspan, Robert S Lee, Ankit Vishnubhotla, Michael Schartner, Julia M Huntenburg, Anup Khanal, Guido T Meijer, Jean-Paul Noel, Alejandro Pan-Vazquez, Karolina Z Socha, Anne E Urai, The International Brain Laboratory, Richard Warren, Dillon Noone, Federico Pedraja, John Cunningham, […]
Kavli Affiliate: Loyal Goff | Authors: Subhash Kulkarni, Monalee Saha, Jared Slosberg, Alpana Singh, Sushma Nagaraj, Laren S Becker, Chengxiu Zhang, Alicia Bukowski, Zhuolun Wang, Guosheng Liu, Jenna Leser, Mithra Kumar, Shriya Bakhshi, Matthew J Anderson, Mark Lewandoski, Elizabeth Vincent, Loyal Goff and Pankaj Jay Pasricha | Summary: The enteric nervous system (ENS), a collection […]
Kavli Affiliate: Seth Shipman | Authors: Sierra K Lear, Jose A Nunez and Seth L Shipman | Summary: Efficient metabolic engineering and the development of mitochondrial therapeutics often rely upon the specific and strong import of foreign proteins into mitochondria. Fusing a protein to a mitochondria-bound signal peptide is a common method to localize proteins […]
Kavli Affiliate: Joshua Vogelstein | Authors: Jaewon Chung, Eric W Bridgeford, Michael Powell and Joshua T Vogelstein | Summary: The heritability of human connectomes is crucial for understanding the genetic and environmental factors that influence variations in connectomes, which can provide insights into behavior and disease. However, current approaches to studying connectome heritability assume an […]
Kavli Affiliate: Ekaterina V. Vinogradova | Authors: Ekaterina Vinogradova, Alisa Mikhaylina, Oleg Nikonov and Ekaterina Nikonova | Summary: Aminoacyl-tRNA synthetases (aaRS) are the main enzymes of protein biosynthesis. Human glycyl-tRNA synthetase, in addition to the main function of amino acid transfer to the corresponding tRNA molecules, is also involved in the initiation of IRES I […]
Kavli Affiliate: Laurent Younes, Michael Miller, Jean Fan | Authors: Kaitlin M Stouffer, Alain Trouve, Laurent Younes, Michael Kunst, Lydia Ng, Hongkui Zeng, Manjari Anant, Jean Fan, Yongsoo Kim and Michael I Miller | Summary: This paper explicates a solution to the problem of building correspondences between molecular-scale transcriptomics and tissue-scale atlases. The central model […]