Kavli Affiliate: Michael Miller, Menno Witter | Authors: Kaitlin Stouffer, Menno Witter, Daniel Tward and Michael Miller | Summary: Reconstructing dense 3D anatomical coordinates from 2D projective measurements has become a central problem in both mouse and human digital pathology. We describe a new family of diffeomorphic mapping technologies called Projective LDDMM which generate diffeomorphic […]
Kavli Affiliate: Winrich Freiwald | Authors: Ben Deen and Winrich A Freiwald | Summary: What is the cognitive and neural architecture for high-level reasoning? We hypothesize that systems for understanding people and places remain separate throughout the brain, but share a parallel organization. We test this hypothesis using deep neuroimaging of individual human brains on […]
Kavli Affiliate: Loyal Goff | Authors: Elizabeth Vincent, Sumantra Chatterjee, Gabrielle H Cannon, Dallas Auer, Holly Ross, Aravinda Chakravarti and Loyal A Goff | Summary: The receptor tyrosine kinase gene RET plays a critical role in the fate specification of enteric neural crest-derived cells (ENCDCs) during enteric nervous system (ENS) development. Pathogenic RET loss of […]
Kavli Affiliate: Wei Min | Authors: Daniel J.M. Crouch, Jamie R.J. Inshaw, Catherine C. Robertson, Jia-Yuan Zhang, Wei-Min Chen, Suna Onengut-Gumuscu, Antony J. Cutler, Carlo Sidore, Francesco Cucca, Flemming Pociot, Patrick Concannon, Steven S. Rich and John A. Todd | Summary: For polygenic traits, associations with genetic variants can be detected over many chromosome regions, […]
Kavli Affiliate: Joerg Bewersdorf | Authors: Andrew E. S. Barentine, Yu Lin, Edward M Courvan, Phylicia Kidd, Miao Liu, Leonhard Balduf, Timy Phan, Felix Rivera-Molina, Michael R. Grace, Zach Marin, Mark Lessard, Juliana Rios-Chen, Siyuan Wang, Karla M Neugebauer, Joerg Bewersdorf and David Baddeley | Summary: Diffraction-unlimited single-molecule techniques like STORM and (F)PALM enable three-dimensional […]
Kavli Affiliate: Paul Greengard | Authors: Ana Milosevic, Lucian Medrihan, Margarete Knudsens, Tatiana Ferraro, Pedro Del Cioppo Vasques, Yevgeniy Romin, Sho Fujisawa and Paul Greengard | Summary: The cholinergic interneurons (ChATs) of the nucleus accumbens (NAc) have a critical role in the activity of this region, specifically in the context of major depressive disorder. To […]
Kavli Affiliate: V. S. Ramachandran | Authors: Victoria Paradise, Malavika Sabu, Joanna Bafia, Nyle A Sharif, Chi Nguyen, Rijuta Dhanraj Mukim, Kalin D Konrad-Vicario, Xiao Wang, Bianca T Corjuc, Jack Fu, Gabriella Maldonado, Jeffrey Ndubisi, Michael Strickland, Helen Figueroa, Douglas L Almeida, Bradley T Hyman, David M Holtzman, Tal Nuriel and Kapil V Ramachandran | […]
Kavli Affiliate: Jean Laurent Casanova | Authors: Peng Zhang, Quentin Philippot, Weicheng Ren, Wei-Te Lei, Juan Li, Peter D. Stenson, Pere Soler Palacín, Roger Colobran, Bertrand Boisson, Shen-Ying Zhang, Anne Puel, Qiang Pan-Hammarström, Qian Zhang, David N. Cooper, Laurent Abel and Jean-Laurent Casanova | Summary: Pre-mRNA splicing is initiated with the recognition of a single-nucleotide […]
Kavli Affiliate: Yasser Roudi, Ivan Davidovich | Authors: Ivan A. Davidovich and Yasser Roudi | Summary: Power laws arise in a variety of phenomena ranging from matter undergoing phase transition to the distribution of word frequencies in the English language. Usually, their presence is only apparent when data is abundant, and accurately determining their exponents […]
Kavli Affiliate: Cori Bargmann | Authors: Javier Marquina-Solis, Elke Vandewyver, Josh Hawk, Daniel Colon-Ramos, Isabel Beets and Cori Bargmann | Summary: Pathogenic infection elicits sickness behaviors that promote recovery and survival of the host. For example, following infection with the pathogenic bacterium Pseudomonas aeruginosa PA14, the nematode Caenorhabditis elegans modifies its sensory preferences to avoid […]