Kavli Affiliate: Roderick MacKinnon | Authors: George Vaisey, Priyam Banerjee, Alison J North, Christoph A Haselwandter and Roderick MacKinnon | Summary: Summary Piezo1 is the stretch activated Ca2+ channel in red blood cells that mediates homeostatic volume control. Here we study the organization of Piezo1 in red blood cells using a combination of super resolution […]
Kavli Affiliate: Wesley Thompson | Authors: Tzu-Hsuan Huang, Chun Chieh Fan, Wesley Thompson and Robert Loughnan | Summary: Abstract Magnetic resonance imaging (MRI) studies of the human brain are now attaining larger sample sizes with more diverse samples. However, population stratification, a key factor driving heterogeneity and confounding of associations, is seldom accounted for in […]
Kavli Affiliate: Li Zhao | Authors: Samuel Khodursky, Caroline S Jiang, Eric B Zheng, Roger Vaughan, Daniel R Schrider and Li Zhao | Summary: Abstract Understanding phenotypic sex differences has long been a goal of biology from both a medical and evolutionary perspective. Although much attention has been paid to mean differences in phenotype between […]
Kavli Affiliate: Terry Jernigan & Anders Dale | Authors: Diliana Pecheva, John R Iversen, Clare E Palmer, Richard Watts, Terry L Jernigan, Donald J Hagler and Anders M Dale | Summary: Abstract The Adolescent Brain and Cognitive Development (ABCD) study aims to measure the trajectories of brain, cognitive, and emotional development. Cognitive and behavioural development […]
Kavli Affiliate: Christina Gremel | Authors: Christian Cazares, Drew C. Schreiner, Mariela Lopez Valencia and Christina M. Gremel | Summary: Summary The ability to use information from one’s prior actions is necessary for decision-making. While Orbitofrontal cortex (OFC) has been hypothesized as key for inferences made using cue and value-related information, whether OFC populations contribute […]
Kavli Affiliate: Robert Clark | Authors: Robert Clark Penner | Summary: Abstract This survey summarizes several works by the author on protein geometry and protein function with applications to viral glycoproteins in general and the spike glycoprotein of the SARS-CoV-2 virus in particular. Though a certain level of mathematical sophistication is assumed, the background biology […]
Kavli Affiliate: Kristina Nielsen and Charles Connor | Authors: Alexandriya MX Emonds, Ramanujan Srinath, Kristina J Nielsen and Charles E Connor | Summary: ABSTRACT When your head tilts laterally, as in sports, reaching, and resting, your eyes counterrotate less than 20%, and thus eye images rotate, over a total range of about 180°. Yet, the […]
Kavli Affiliate: Angela Wu | Authors: The Tabula Microcebus Consortium, Camille Ezran, Shixuan Liu, Jingsi Ming, Lisbeth A. Guethlein, Michael F. Z. Wang, Roozbeh Dehghannasiri, Julia Olivieri, Hannah K. Frank, Alexander Tarashansky, Winston Koh, Qiuyu Jing, Olga Botvinnik, Jane Antony, Stephen Chang, Angela Oliveira Pisco, Jim Karkanias, Can Yang, James E. Ferrell, Jr., Scott D. […]
Kavli Affiliate: Hana El-Samad | Authors: Lindsey C Osimiri, Alain R Bonny, Seesha R Takagishi, Stefanie Luecke, Nina Riehs, Alexander Hoffmann and Hana El-Samad | Summary: Abstract Many transcription factors (TFs) translocate to the nucleus with varied dynamic patterns in response to different inputs. A notable example of such behavior is RelA, a subunit of […]
Kavli Affiliate: Xin Duan | Authors: Alicia N Vagnozzi, Matthew T Moore, Minshan Lin, Elyse M Brozost, Ritesh KC, Aambar Agarwal, Lindsay A Schwarz, Xin Duan, Niccolò Zampieri, Lynn T Landmesser and Polyxeni Philippidou | Summary: Abstract Breathing, and the motor circuits that control it, are essential for life. At the core of respiratory circuits […]