Kavli Affiliate: Michael Miller | Authors: Han Zhu, Gaowei Wang, Kim-Vy Nguyen-Ngoc, Dongsu Kim, Michael Miller, Georgina Goss, Jenna Kovsky, Austin R Harrington, Diane Saunders, Rebecca Melton, Alvin C Powers, Sebastian Preissl, Francesca M Spagnoli, Kyle J Gaulton and Maike Sander | Summary: Abstract Pancreatic islet cells derived from human pluripotent stem cells hold great […]
Kavli Affiliate: Mark Ellisman | Authors: Hugo Calligaro, Azarin Shoghi, Xinyue Chen, Keun-Young Kim, Yu Hsin Liu, Brian Khov, Benjamin Finander, Hiep Le, Mark H Ellisman and Satchidananda Panda | Summary: Abstract The suprachiasmatic nucleus (SCN) in the hypothalamus of the vertebrate brain is the central pacemaker regulating circadian rhythmicity throughout the body. The SCN […]
Kavli Affiliate: Fred Gage | Authors: Sarah L Parylak, Fan Qiu, Sara B Linker, Iryna S Gallina, Christina K Lim, David Preciado, Aidan H McDonald and Fred H Gage | Summary: Abstract Immature dentate granule cells (DGCs) generated in the hippocampus during adulthood are believed to play a unique role in dentate gyrus function. Although […]
Kavli Affiliate: Vy Thuy Nguyen | Authors: Mollie Friedlander Qian, Romina J Bevacqua, Vy M Nguyen, Xiong Liu, Weichen Zhao, Charles A Chang, Xueying Gu, Xiao-Qing Dai, Patrick E Macdonald and Seung K. Kim | Summary: ABSTRACT HNF1A haploinsufficiency underlies the most common form of human monogenic diabetes (HNF1A-MODY) and hypomorphic HNF1A variants confer type […]
Kavli Affiliate: Donald Geman, Laurent Younes | Authors: Kun Yang, Koko Ishizuka, Zui Narita, Yukiko Y Lema, Siwei Zhang, Jubao Duan, Laurent Younes, Donald Geman, Andrew P Lane and Akira Sawa | Summary: ABSTRACT Biopsy is an essential procedure of clinical medicine in which we obtain tissues and cells that are supposed to directly reflect […]
Kavli Affiliate: Michael Miller | Authors: MoTrPAC Study Group, David Amar, Nicole R. Gay, Pierre M. Jean Beltran, Joshua N. Adkins, Jose J. Almagro Armenteros, Euan Ashley, Julian Avila-Pacheco, Dam Bae, Nasim Bararpour, Charles Burant, Clary Clish, Gary Cutter, Surendra Dasari, Courtney Dennis, Charles R. Evans, Facundo M. Fernández, David Gaul, Yongchao Ge, Robert Gerszten, […]
Kavli Affiliate: C. Daniel Salzman | Authors: David L Barack, Akram Bakkour, Daphna Shohamy and C Daniel Salzman | Summary: Abstract In the real world, making sequences of decisions to achieve goals often depends upon the ability to learn aspects of the environment that are not directly perceptible. Learning these so-called latent features requires seeking […]
Kavli Affiliate: Costa, Rui | Authors: Lina Marcela Carmona, Lin T Tun, An Kim, Rani Shiao, Michael D Kissner, Vilas Menon and Rui M Costa | Summary: ABSTRACT The primary motor cortex (M1) is a central hub for motor learning and execution, as it receives input from and broadcasts to a multitude of other motor […]
Kavli Affiliate: Costa, Rui | Authors: Jonathan C.Y. Tang, Vitor Paixao, Filipe Carvalho, Artur Silva, Andreas Klaus, Joaquim Alves da Silva and Rui M Costa | Summary: Abstract Animals exhibit a diverse behavioral repertoire when exploring new environments and can learn which actions or action sequences produce positive outcomes. Dopamine release upon encountering reward is […]
Kavli Affiliate: Jeffrey Friedman | Authors: Anoj Ilanges, Mengyu Xia, Junmei Lu, Lei Chen, Rani Shiao, Changchun Wang, Ru Feng, Zheyu Jin, Han Yi, Qingqing Qi, Jixi Li, Marc Schneeberger, Boxun Lu, Jeffrey M. Friedman and Xiaofei Yu | Summary: Summary Psychological stress and its sequelae are a major public health problem. While the immune […]