Flexible neural control of motor units

Kavli Affiliate: Mark Churchland, Michael Shadlen | Authors: Najja J. Marshall, Joshua I. Glaser, Eric M. Trautmann, Elom A. Amematsro, Sean M. Perkins, Michael N. Shadlen, L. F. Abbott, John P. Cunningham and Mark M. Churchland | Summary: Voluntary movement requires communication from cortex to the spinal cord, where a dedicated pool of motor units […]


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Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq

Kavli Affiliate: Jean Laurent Casanova | Authors: Sara E Vazquez, Sabrina A Mann, Aaron Bodansky, Andrew F Kung, Zoe Quandt, Elise M N Ferré, Nils Landegren, Daniel Eriksson, Paul Bastard, Shen-Ying Zhang, Jamin Liu, Anthea Mitchell, Caleigh Mandel-Brehm, Brenda Miao, Gavin Sowa, Kelsey Zorn, Alice Y Chan, Chisato Shimizu, Adriana Tremoulet, Kara Lynch, Michael R […]


Continue.. Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq

MRSCloud: a Cloud-based MR Spectroscopy Tool for Basis Set Simulation

Kavli Affiliate: Susumu Mori | Authors: Steve C.N. Hui, Muhammad Saleh, Helge J Zoellner, Georg Oeltzschner, Hongli Fan, Yue Li, Yulu Song, Hangyi Jiang, Jamie Near, Hanzhang Lu, Susumu Mori and Richard Edden | Summary: Background Accurate quantification of in vivo proton magnetic resonance spectra involves modeling with a linear combination of known metabolite basis […]


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Motor cortex activity across movement speeds is predicted by network-level strategies for generating muscle activity

Kavli Affiliate: Mark Churchland | Authors: Shreya Saxena, Abigail Russo, John Cunningham and Mark M Churchland | Summary: Learned movements can be skillfully performed at different paces. What neural strategies produce this flexibility? Can they be predicted and understood by network modeling? We trained monkeys to perform a cycling task at different speeds, and trained […]


Continue.. Motor cortex activity across movement speeds is predicted by network-level strategies for generating muscle activity

Global Spatial Transcriptome of Macaque Brain at Single-Cell Resolution

Kavli Affiliate: Li Zhao | Authors: Ao Chen, Yidi Sun, Ying Lei, Chao Li, Sha Liao, Zhifeng Liang, Feng Lin, Nini Yuan, Mei Li, Kexin Wang, Meisong Yang, Shuzhen Zhang, Zhenkun Zhuang, Juan Meng, Qiong Song, Yong Zhang, Yuanfang Xu, Luman Cui, Lei Han, Hao Yang, Xing Sun, Tianyi Fei, Bichao Chen, Wenjiao Li, Baoqian […]


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Multi-finger Receptive Field Properties in Primary Somatosensory Cortex: A Revised Account of the Spatio-Temporal Integration Functions of Area 3b

Kavli Affiliate: Charles Connor | Authors: Natalie K Trzcinski, Steven S Hsiao, Charles E Connor and Manuel Gomez-Ramirez | Summary: The leading view in the somatosensory system indicates that area 3b serves as a cortical relay site that encodes cutaneous (tactile) features limited to individual digits. Our recent work argues against this model by showing […]


Continue.. Multi-finger Receptive Field Properties in Primary Somatosensory Cortex: A Revised Account of the Spatio-Temporal Integration Functions of Area 3b

Interplay between rule learning and rule switching in a perceptual categorization task

Kavli Affiliate: Marcelo Mattar | Authors: Flora Bouchacourt, Sina Tafazoli, Marcelo Gomes Mattar, Timothy J Buschman and Nathaniel Douglass Daw | Summary: To adapt to a changing world, we must be able to switch between rules already learned and, at other times, learn rules anew. Often we must do both at the same time, switching […]


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Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages

Kavli Affiliate: Terry Jernigan | Authors: Amirhossein Modabbernia, Didac Vidal-Pineiro, Ingrid Agartz, Ole A Andreassen, Rosa Ayesa-Arriola, Alessandro Bertolino, Dorret I Boomsma, Josiane Bourque, Alan Breier, Rachel M Brouwer, Jan K Buitelaar, Erick J Canales-Rodriguez, Xavier Caseras, Patricia J Conrod, Benedicto Crespo-Facorro, Fabrice Crivello, Eveline A Crone, Greig I de Zubicaray, Erin W Dickie, Danai […]


Continue.. Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages

Adversarial domain translation networks for fast and accurate integration of large-scale atlas-level single-cell datasets

Kavli Affiliate: Angela Wu | Authors: Jia Zhao, Gefei Wang, Jingsi Ming, Zhixiang Lin, Yang Wang, The Tabula Microcebus Consortium, Angela Ruohao Wu and Can Yang | Summary: The rapid emergence of large-scale atlas-level single-cell RNA-seq datasets presents remarkable opportunities for broad and deep biological investigations through integrative analyses. However, harmonizing such datasets requires integration […]


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ASD modelling in organoids reveals imbalance of excitatory cortical neuron subtypes during early neurogenesis

Kavli Affiliate: Flora Vaccarino | Authors: Alexandre Jourdon, Feinan Wu, Jessica Mariani, Davide Capauto, Scott Norton, Livia Tomasini, Anahita Amiri, Milovan Suvakov, Jeremy Schreiner, Yeongjun Jang, Cindy Khanh Nguyen, Elise M Cummings, Gloria Han, Kelly Powell, Anna Szekely, James C McPartland, Kevin Pelphrey, Katarzyna Chawarska, Pamela Ventola, Alexej Abyzov and Flora M Vaccarino | Summary: […]


Continue.. ASD modelling in organoids reveals imbalance of excitatory cortical neuron subtypes during early neurogenesis