A multifaceted architectural framework of the mouse claustrum complex

Kavli Affiliate: Clifford Kentros, Menno Witter, Stefan Blankvoort | Authors: Joachim Schweder Grimstvedt, Andrew M. Shelton, Anna Hoerder-Suabedissen, David K. Oliver, Christin H. Berndtsson, Stefan Blankvoort, Rajeevkumar Raveendran Nair, Adam M. Packer, Menno P. Witter and Clifford G. Kentros | Summary: Accurate anatomical characterizations are necessary to investigate neural circuitry on a fine scale, but […]


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Hippocampal-medial entorhinal circuit is differently organized along the dorsoventral axis in rodents

Kavli Affiliate: Menno Witter | Authors: Shinya Ohara, Märt Rannap, Ken-Ichiro Tsutsui, Andreas Draguhn, Alexei V. Egorov and Menno P. Witter | Summary: The general understanding of hippocampal circuits is that the hippocampus and the entorhinal cortex (EC) are topographically connected through parallel identical circuits along the dorsoventral axis. Our anterograde tracing and in vitro […]


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Persistence of Cajal-Retzius cells in the postnatal hippocampus is required for development of dendritic spines of CA1 pyramidal cells

Kavli Affiliate: Maximiliano Nigro, Giulia Quattrocolo, Keagan Dunville | Authors: Ingvild Lynneberg Glaerum, Keagan Dunville, Nicola Pietro Montaldo, Hinako Kirikae, Maximiliano Jose Nigro, Pal Saetrom, Barbara Van Loon and Giulia Quattrocolo | Summary: Cajal-Retzius (CR) cells are a transient type of neuron that populate the postnatal hippocampus. The role of transient cell types and circuits […]


Continue.. Persistence of Cajal-Retzius cells in the postnatal hippocampus is required for development of dendritic spines of CA1 pyramidal cells

m6A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina

Kavli Affiliate: Jingyi Guo | Authors: Yanling xin, Qinghai He, Huilin Liang, Jingyi Guo, Qi Zhong, Ke Zhang, Jinyan Li, Yizhi Liu and Shuyi Chen | Summary: N6-methyladenosine (m6A) is the most prevalent mRNA internal modification and has been shown to regulate the development, physiology and pathology of various tissues. However, the functions of the […]


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Minute-scale oscillatory sequences in medial entorhinal cortex

Kavli Affiliate: Edvard Moser, May Britt Moser, Ragnhild Leifsdottir, Horst Obenhaus | Authors: Soledad Gonzalo Cogno, Horst A. Obenhaus, Ragnhild Irene Jacobsen, Flavio Donato, May-Britt Moser and Edvard I. Moser | Summary: The medial entorhinal cortex (MEC) hosts many of the brain’s circuit elements for spatial navigation and episodic memory, operations that require neural activity […]


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Bayesian interpolation for power laws in neural data analysis

Kavli Affiliate: Yasser Roudi, Ivan Davidovich | Authors: Ivan A. Davidovich and Yasser Roudi | Summary: Power laws arise in a variety of phenomena ranging from matter undergoing phase transition to the distribution of word frequencies in the English language. Usually, their presence is only apparent when data is abundant, and accurately determining their exponents […]


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Social Learning of a Spatial Task by Observation Alone

Kavli Affiliate: Clifford Kentros | Authors: Thomas Doublet, Mona Nosrati and Clifford G. Kentros | Summary: Interactions between conspecifics are central to the acquisition of useful memories in the real world. Observational learning, i.e., learning a task by observing the success or failure of others, has been reported in many species, including rodents. However, previous […]


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Projective LDDMM: Spatially Reconstructing a Story of Rostrally-Dominant Tau in Alzheimer’s Disease

Kavli Affiliate: Michael Miller, Susumu Mori, Menno Witter | Authors: Kaitlin Stouffer, Menno Witter, Claire Chen, Eileen Xu, Marilyn Albert, Susumu Mori, Juan Troncoso, Daniel Jacob Tward and Michael Miller | Summary: Since Braak’s initial histological observations, it has been recognized that Alzheimer’s disease (AD) neurofibrillary tangles (NFTs) appear in the medial temporal lobe (MTL) […]


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Behavioral decomposition reveals rich encoding structure employed across neocortex

Kavli Affiliates: Jingyi Guo, Claudia Battistin, Tuce Tombaz, Bartul Mimica, Jonathan Whitlock | Authors: Bartul Mimica, Tuçe Tombaz, Claudia Battistin, Jingyi Guo Fuglstad, Benjamin A. Dunn and Jonathan R. Whitlock | Summary: The Cortical population code is pervaded by activity patterns evoked by movement, but how such signals relate to the natural actions of unrestrained […]


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HERBS: Histological E-data Registration in rodent Brain Spaces

Kavli Affiliate: Jonathan Whitlock, Jingyi Guo, Pearl Saldanha | Authors: Jingyi Guo Fuglstad, Pearl Saldanha, Jacopo Paglia and Jonathan R. Whitlock | Summary: Abstract Recording technologies for rodents have seen huge advances in the last decade, allowing users to sample thousands of neurons simultaneously from multiple brain regions. This has prompted the need for digital […]


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