Amygdalar and ERC Rostral Atrophy and Tau Pathology Reconstruction in Preclinical Alzheimer’s Disease

Kavli Affiliate: Menno Witter, Susumu Mori, Michael Miller | Authors: Kaitlin Stouffer, Claire Chen, Sue Kulason, Eileen Xu, Menno Witter, Can Ceritoglu, Marilyn Albert, Susumu Mori, Juan Troncoso, Daniel Jacob Tward and Michael I Miller | Summary: Previous research has emphasized the unique impact of Alzheimer’s Disease (AD) pathology on the medial temporal lobe (MTL), […]


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Klarigi: Characteristic Explanations for Semantic Data

Kavli Affiliate: Simon Ball | Authors: Luke T Slater, John A Williams, Paul N Schofield, Sophie Russell, Samantha C Pendleton, Andreas Karwath, Hilary Fanning, Simon Ball, Robert T Hoehndorf and Georgios V Gkoutos | Summary: Abstract Background Annotation of biomedical entities with ontology terms facilitates the use of background knowledge in analysis. Described entities may […]


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A multifaceted architectural framework of the mouse claustrum complex

Kavli Affiliate: Clifford Kentros, Menno Witter, Stefan Blankvoort | Authors: Joachim Schweder Grimstvedt, Andrew M. Shelton, Anna Hoerder-Suabedissen, David K. Oliver, Christin H. Berndtsson, Stefan Blankvoort, Rajeevkumar Raveendran Nair, Adam M. Packer, Menno P. Witter and Clifford G. Kentros | Summary: Accurate anatomical characterizations are necessary to investigate neural circuitry on a fine scale, but […]


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Hippocampal-medial entorhinal circuit is differently organized along the dorsoventral axis in rodents

Kavli Affiliate: Menno Witter | Authors: Shinya Ohara, Märt Rannap, Ken-Ichiro Tsutsui, Andreas Draguhn, Alexei V. Egorov and Menno P. Witter | Summary: The general understanding of hippocampal circuits is that the hippocampus and the entorhinal cortex (EC) are topographically connected through parallel identical circuits along the dorsoventral axis. Our anterograde tracing and in vitro […]


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Persistence of Cajal-Retzius cells in the postnatal hippocampus is required for development of dendritic spines of CA1 pyramidal cells

Kavli Affiliate: Maximiliano Nigro, Giulia Quattrocolo, Keagan Dunville | Authors: Ingvild Lynneberg Glaerum, Keagan Dunville, Nicola Pietro Montaldo, Hinako Kirikae, Maximiliano Jose Nigro, Pal Saetrom, Barbara Van Loon and Giulia Quattrocolo | Summary: Cajal-Retzius (CR) cells are a transient type of neuron that populate the postnatal hippocampus. The role of transient cell types and circuits […]


Continue.. Persistence of Cajal-Retzius cells in the postnatal hippocampus is required for development of dendritic spines of CA1 pyramidal cells

m6A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina

Kavli Affiliate: Jingyi Guo | Authors: Yanling xin, Qinghai He, Huilin Liang, Jingyi Guo, Qi Zhong, Ke Zhang, Jinyan Li, Yizhi Liu and Shuyi Chen | Summary: N6-methyladenosine (m6A) is the most prevalent mRNA internal modification and has been shown to regulate the development, physiology and pathology of various tissues. However, the functions of the […]


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Single neurons and networks in the claustrum integrate input from widespread cortical sources

Kavli Affiliate: Clifford Kentros, Menno Witter | Authors: Andrew M Shelton, David K Oliver, Joachim S Grimstvedt, Ivan P Lazarte, Ishaan Kapoor, Jake A Swann, Caitlin A Ashcroft, Simon N Williams, Niall Conway, Amy Robinson, Clifford G Kentros, Menno P Witter, Simon JB Butt and Adam M Packer | Summary: The claustrum is highly interconnected […]


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Minute-scale oscillatory sequences in medial entorhinal cortex

Kavli Affiliate: Edvard Moser, May Britt Moser, Ragnhild Leifsdottir, Horst Obenhaus | Authors: Soledad Gonzalo Cogno, Horst A. Obenhaus, Ragnhild Irene Jacobsen, Flavio Donato, May-Britt Moser and Edvard I. Moser | Summary: The medial entorhinal cortex (MEC) hosts many of the brain’s circuit elements for spatial navigation and episodic memory, operations that require neural activity […]


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Bayesian interpolation for power laws in neural data analysis

Kavli Affiliate: Yasser Roudi, Ivan Davidovich | Authors: Ivan A. Davidovich and Yasser Roudi | Summary: Power laws arise in a variety of phenomena ranging from matter undergoing phase transition to the distribution of word frequencies in the English language. Usually, their presence is only apparent when data is abundant, and accurately determining their exponents […]


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Social Learning of a Spatial Task by Observation Alone

Kavli Affiliate: Clifford Kentros | Authors: Thomas Doublet, Mona Nosrati and Clifford G. Kentros | Summary: Interactions between conspecifics are central to the acquisition of useful memories in the real world. Observational learning, i.e., learning a task by observing the success or failure of others, has been reported in many species, including rodents. However, previous […]


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