Direct Entorhinal Control of CA1 Temporal Coding

Kavli Affiliate: Clifford Kentros | Authors: Matteo Guardamagna, Oscar M.T. Chadney, Federico Stella, Qiangwei Zhang, Clifford Kentros and Francesco P. Battaglia | Summary: Local computations of CA1 neurons are shaped by two direct input streams, from CA3 and EC LIII. By specifically silencing the direct input from the entorhinal cortex, we found that single-cell temporal […]


Continue.. Direct Entorhinal Control of CA1 Temporal Coding

Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling

Kavli Affiliate: Menno Witter | Authors: Katrine Sjaastad Hanssen, Nicolai Winter-Hjelm, Salome Nora Niethammer, Asgeir Kobro-Flatmoen, Menno P. Witter, Axel Sandvig and Ioanna Sandvig | Summary: Engineered biological neural networks are indispensable tools for investigating neural function in both healthy and diseased states from the subcellular to the network level. Neurons in vitro self-organize over […]


Continue.. Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling

Foxj1 controls olfactory ciliogenesis and differentiation program of the olfactory sensory neurons

Kavli Affiliate: Emre Yaksi | Authors: Dheeraj Rayamajhi, Mert Ege, Kirill Ukhanov, Christa Ringers, Yiliu Zhang, Inyoung Jeong, Percival P D’Gama, Summer Shijia Li, Mehmet Ilyas Cosacak, Caghan Kizil, Hae-Chul Park, Emre Yaksi, Jeffrey R Martens, Steven L Brody, Nathalie Jurisch-Yaksi and Sudipto Roy | Summary: In vertebrates, olfactory receptors localize on multiple cilia elaborated […]


Continue.. Foxj1 controls olfactory ciliogenesis and differentiation program of the olfactory sensory neurons

The influence of environment geometry on subiculum boundary vector cells in adulthood and early development

Kavli Affiliate: Edvard Moser, May-Britt Moser | Authors: Laurenz Muessig, Fabio Ribeiro Rodrigues, Tale Bjerknes, Ben Towse, Caswell Barry, Neil Burgess, Edvard I Moser, May-Britt Moser, Francesca Cacucci and Thomas J Wills | Summary: Boundaries to movement form a specific class of landmark information used for navigation. Boundary Vector Cells (BVCs) are neurons which encode […]


Continue.. The influence of environment geometry on subiculum boundary vector cells in adulthood and early development

Single-cell RNA sequencing analyses of primary cutaneous B-cell disorders reveal distinct molecular patterns consistent with clinical behavior

Kavli Affiliate: Vy Thuy Nguyen | Authors: Johannes Griss, Mathias C Drach, Vy Nguyen, Jasmine P Levine, Felix Thaler, Marco A Medjimorec, Lisa E Shaw, Ulrike Mann, Wolfgang Weninger, Christine Wagner, Stephan Wagner, Ingrid Simonitsch-Klupp, Matthias Farlik, Constanze Jonak and Patrick M Brunner | Summary: Cutaneous B-cell lymphomas (CBL) comprise a diverse group of diseases […]


Continue.. Single-cell RNA sequencing analyses of primary cutaneous B-cell disorders reveal distinct molecular patterns consistent with clinical behavior

Visuomotor interactions in the mouse forebrain mediated by extrastriate cortico-cortical pathways

Kavli Affiliate: Menno Witter, Jonathan Whitlock | Authors: Karoline Hovde, Ida V. Rautio, Andrea Marie Hegstad, Menno P. Witter and Jonathan R. Whitlock | Summary: Abstract The mammalian visual system can be broadly divided into two functional processing pathways: a dorsal stream supporting visually and spatially guided actions, and a ventral stream enabling object recognition. […]


Continue.. Visuomotor interactions in the mouse forebrain mediated by extrastriate cortico-cortical pathways

Microdissection and culturing of adult lateral entorhinal cortex layer II neurons from APP/PS1 Alzheimer model mice

Kavli Affiliate: Menno Witter, Asgeir Kobro-Flatmoen | Authors: Katrine Sjaastad Hanssen, Menno P. Witter, Axel Sandvig, Ioanna Sandvig and Asgeir Kobro-Flatmoen | Summary: Abstract Background Primary neuronal cultures enable cell-biological studies of Alzheimer’s disease (AD), albeit typically non-neuron-specific. The first cortical neurons affected in AD reside in layer II of the lateralmost part of the […]


Continue.. Microdissection and culturing of adult lateral entorhinal cortex layer II neurons from APP/PS1 Alzheimer model mice

A selectivity filter in the EMC limits protein mislocalization to the ER

Kavli Affiliate: Vy Thuy Nguyen | Authors: Tino Pleiner, Masami Hazu, Giovani Pinton Tomaleri, Vy N. Nguyen, Kurt Januszyk and Rebecca M. Voorhees | Summary: SUMMARY Tail anchored proteins (TAs) play essential roles at both the ER and mitochondria, and their accurate localization is critical to proteostasis. Biophysical similarities lead to mistargeting of mitochondrial TAs […]


Continue.. A selectivity filter in the EMC limits protein mislocalization to the ER

Long-range inhibitory axons from medial entorhinal cortex target lateral entorhinal neurons projecting to the hippocampus

Kavli Affiliate: Bente Jacobsen, Menno Witter, Eirik Nilssen | Authors: Eirik S. Nilssen, Bente Jacobsen, Thanh P. Doan, Paulo J.B. Girao and Menno P. Witter | Summary: ABSTRACT Functionally distinct information encoded by the two main divisions of the entorhinal cortex (EC), the lateral EC (LEC) and the medial EC (MEC), is thought to be […]


Continue.. Long-range inhibitory axons from medial entorhinal cortex target lateral entorhinal neurons projecting to the hippocampus

Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids

Kavli Affiliate: Vy Thuy Nguyen | Authors: Kim Vy Nguyen Ngoc, Somesh Sai, Yesl Jun, R. Hugh F. Bender, Vira Kravets, Han Zhu, Christopher J Hatch, Michael Schlichting, Roberto Gaetani, Medhavi Mallick, Stephanie J Hachey, Karen Christman, Steven Carl George, Christopher C Hughes and Maike Sander | Summary: Abstract Blood vessels play a critical role […]


Continue.. Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids