Kavli Affiliate: Edvard Moser and May-Britt Moser | Authors: Christine M Lykken, Benjamin R Kanter, Anne Nagelhus, Jordan Carpenter, Matteo Guardamagna, Edvard I Moser and May-Britt Moser | Summary: A systems-level understanding of cortical computation requires insight into how neural codes are transformed across distinct brain circuits. In the mammalian cortex, one of the few […]
Kavli Affiliate: Emre Yaksi | Authors: Anh-Tuan Trinh, Anna Maria Ostenrath, Ignacio del Castillo-Berges, Susanne Kraus, Fanchon Cachin, Bram Serneels, Koichi Kawakami and Emre Yaksi | Summary: Thalamocortical projections contribute to the spatial organization and functional hierarchies of the mammalian cortex. Primary sensory cortices receive topographically segregated information from first-order thalamic nuclei, which process distinct […]
Kavli Affiliate: Menno Witter | Authors: Eirik S. Nilssen, Bente Jacobsen, Thanh P. Doan, Paulo J.B. Girao and Menno P. Witter | Summary: ABSTRACT The functionally different lateral entorhinal cortex (LEC) and medial entorhinal cortex (MEC) are strongly interconnected. The role of this interconnectivity in view of their functional differences is not known. Here we […]
Kavli Affiliate: Maximiliano Jose Nigro | Rejwan Hamza Farhad Salih, Luis Fernando Cobar, Francois Philippe Pauzin, Davide Zoccolan and Maximiliano Jose Nigr | Summary: Abstract Sensory processing in the cortex follows a hierarchical structure, transforming fine-grained stimulus features into abstract, invariant representations. These transformations have typically been characterised in visual pathways ranging from primary visual […]
Kavli Affiliate: Valentina Di Maria | Authors: Daniel P. Moore, Heather B. Steele-Stallard, Luca Pinton, Valentina Maria Lionello, Lucia Rossi, Artadokht Aghaeipour, Salma Jalal, Cherry Tsz Yan Wong, Angela Clara-Hwang, Gisèle Bonne, Peter S. Zammit and Francesco Saverio Tedesco | Summary: LMNA-related congenital muscular dystrophy (L-CMD) is amongst the most severe forms of laminopathies, which […]
Kavli Affiliate: Jonathan Whitlock | Authors: Marcia Becu, Ivan Markel Krasovec, Pearl Saldanha, Jonathan Whitlock and Christian F Doeller | Summary: Vector-based spatial coding has been demonstrated in rodents, yet its neural basis in humans and its contribution to navigation remain poorly understood. Using a novel spatial updating task, we show that egocentric directional signals […]
Kavli Affiliate: Maryam Ziaei | Authors: Arjun Dave, Shuer Ye, Leona R Batz, Xiaqing Lan, Heidi Jacobs and Maryam Ziaei | Summary: Interpreting ambiguous environmental cues, like facial expressions, becomes increasingly challenging with age, especially as cognitive resources decline. Managing these challenges requires adaptive neural mechanisms that are essential for maintaining mental well-being. The locus […]
Kavli Affiliate: Maryam Ziaei | Authors: Shuer Ye, Arjun Dave, Alireza Salami and Maryam Ziaei | Summary: Functional dedifferentiation, a hallmark of brain aging particularly evident within the frontoparietal network (FPN), has been extensively investigated in the context of cognitive decline, yet its implications for late-life mental health remain poorly understood. Leveraging naturalistic fMRI combined […]
Kavli Affiliate: Giulia Quattrocolo | Authors: Kristian Moan, Robert P Machold and Giulia Quattrocolo | Summary: Cajal-Retzius (CR) cells are glutamatergic neurons that transiently populate the most superficial layer of the isocortex and allocortex during development, serving an essential role during both prenatal and early postnatal brain development. Notably, these cells disappear from most cortical […]
Kavli Affiliate: Emre Yaksi | Authors: Aytac Kadir Mutlu, Bram Serneels, Christoph Wiest, Anh-Tuan Trinh, Ricarda Bardenhewer, Fabrizio Palumbo, Oda Bjornevik Frisvold, Inger Kristine Fjeldskaar Aukrus, Anna Maria Ostenrath and Emre Yaksi | Summary: The dorsal raphe nucleus (DRN) plays an important role in shaping a wide range of behaviors, including mood, motivation, appetite, sleep, […]