Dorsal-caudal and ventral hippocampus target different cell populations in the medial frontal cortex in rodents

Kavli Affiliate: Menno Witter | Authors: Paola Alemán-Andrade, Menno P. Witter, Ken-Ichiro Tsutsui and Shinya Ohara | Summary: Direct projections from the ventral hippocampus (vHPC) to the medial frontal cortex (MFC) play crucial roles in memory and emotional regulation. Using anterograde transsynaptic tracing and in vitro electrophysiology in mice, we document a previously unexplored pathway […]


Continue.. Dorsal-caudal and ventral hippocampus target different cell populations in the medial frontal cortex in rodents

Inhibition mediated by group III mGluRs regulates habenula activity and defensive behaviors

Kavli Affiliate: Emre Yaksi | Authors: Anna Maria Ostenrath, Nicholas Faturos, Yagnur Isik Ciftci Cobanoglu, Bram Serneels, Inyoung Jeong, Anja Enz, Francisca Hinrichsen, Aytac Kadir Mutlu, Ricarda Bardenhewer, Suresh Kumar Jetti, Stephan C. F. Neuhauss, Nathalie Jurisch-Yaksi and Emre Yaksi | Summary: Inhibition contributes to various brain computations from sensory motor transformations to cognitive operations. […]


Continue.. Inhibition mediated by group III mGluRs regulates habenula activity and defensive behaviors

Single neurons and networks in the claustrum integrate input from widespread cortical sources

Kavli Affiliate: Clifford Kentros, Menno Witter | Authors: Andrew M Shelton, David K Oliver, Joachim S Grimstvedt, Ivan P Lazarte, Ishaan Kapoor, Jake A Swann, Caitlin A Ashcroft, Simon N Williams, Niall Conway, Amy Robinson, Clifford G Kentros, Menno P Witter, Simon JB Butt and Adam M Packer | Summary: The claustrum is highly interconnected […]


Continue.. Single neurons and networks in the claustrum integrate input from widespread cortical sources

Event structure sculpts neural population dynamics in the lateral entorhinal cortex

Kavli Affiliate: Edvard Moser and May-Britt Moser | Authors: Benjamin R Kanter, Christine M Lykken, May-Britt Moser and Edvard I. Moser | Summary: Our experience of the world is a continuous stream of events which must be segmented and organized simultaneously at multiple timescales. The neural mechanisms underlying this process remain unknown. Here, we simultaneously […]


Continue.. Event structure sculpts neural population dynamics in the lateral entorhinal cortex

Left-right-alternating theta sweeps in the entorhinal-hippocampal spatial map

Kavli Affiliate: Edvard Moser and May-Britt Moser | Authors: Abraham Z. Vollan, Richard J. Gardner, May-Britt Moser and Edvard I. Moser | Summary: Place cells in the hippocampus and grid cells in the entorhinal cortex are elements of a neural map of self- position. To benefit navigation, this representation must be dynamically related to surrounding […]


Continue.. Left-right-alternating theta sweeps in the entorhinal-hippocampal spatial map

Phylogeny of neocortical-hippocampal projections provides insight in the nature of human memory

Kavli Affiliate: Menno Witter | Authors: Daniel Reznik, Piotr Majka, Marcello GP Rosa, Menno P Witter and Christian F Doeller; | Summary: Throughout mammalian evolution, the hippocampal region, unlike the neocortex, largely preserved its cytoarchitectural organization and its role in mnemonic functions. This contrast raises the possibility that the hippocampal region receives different types of […]


Continue.. Phylogeny of neocortical-hippocampal projections provides insight in the nature of human memory

Increased functional integration of emotional control network in late adulthood

Kavli Affiliate: Maryam Ziaei | Authors: Leona R Baetz, Shuer Ye, Xiaqing Lan and Maryam Ziaei | Summary: Across the adult lifespan, there are changes in how emotions are perceived and regulated. As individuals age, there is an observed improvement in emotion regulation and overall quicker recovery from negative emotions. While previous studies have shown […]


Continue.. Increased functional integration of emotional control network in late adulthood

Reverse Engineering of Feedforward Cortical-Hippocampal Microcircuits for Modelling Neural Network Function and Dysfunction

Kavli Affiliate: Menno Witter | Authors: Katrine Sjaastad Hanssen, Nicolai Winter-Hjelm, Salome Nora Niethammer, Asgeir Kobro-Flatmoen, Menno P. Witter, Axel Sandvig and Ioanna Sandvig | Summary: Engineered biological neural networks are indispensable models for investigation of neural function and dysfunction from the subcellular to the network level. Notably, advanced neuro-engineering approaches are of significant interest […]


Continue.. Reverse Engineering of Feedforward Cortical-Hippocampal Microcircuits for Modelling Neural Network Function and Dysfunction

Cilia-mediated cerebrospinal fluid flow modulates neuronal and astroglial activity in the zebrafish larval brain

Kavli Affiliate: Emre Yaksi | Authors: Percival P D’Gama, Inyoung Jeong, Andreas Moe Nygard, Ahmed Jamali, Emre Yaksi and Nathalie Jurisch-Yaksi | Summary: The brain uses a specialized system to transport cerebrospinal fluid (CSF). This system consists of interconnected ventricles lined by ependymal cells, which generate a directional flow upon beating of their motile cilia. […]


Continue.. Cilia-mediated cerebrospinal fluid flow modulates neuronal and astroglial activity in the zebrafish larval brain

Resilience-driven neural synchrony during naturalistic movie watching: an ultra-high field fMRI study

Kavli Affiliate: Maryam Ziaei | Authors: Shuer Ye, Leona Rahel Batz, Jain Jain, Alireza Salami and Maryam Ziaei | Summary: Sharing others’ emotional states may facilitate the understanding of their well-being characteristics, such as resilience. Despite increasing attention given to resilience for its role in maintaining mental health, the intricacies of its underlying neural correlates […]


Continue.. Resilience-driven neural synchrony during naturalistic movie watching: an ultra-high field fMRI study