Revealing abrupt transitions from goal-directed to habitual behavior

Kavli Affiliate: Kishore V. Kuchibhotla, Adam S. Charles | Authors: Sharlen Moore, Zyan Wang, Ziyi Zhu, Ruolan Sun, Angel Lee, Adam Charles and Kishore V Kuchibhotla | Summary: A fundamental tenet of animal behavior is that decision-making involves multiple ‘controllers.’ Initially, behavior is goal-directed, driven by desired outcomes, shifting later to habitual control, where cues […]


Continue.. Revealing abrupt transitions from goal-directed to habitual behavior

TrkB-dependent regulation of molecular signaling across septal cell types

Kavli Affiliate: Keri Martinowich | Authors: Lionel A Rodriguez, Matt N Tran, Renee Garcia-Flores, Elizabeth A Pattie, Sun-Hong Kim, Joo Heon Shin, Yong Kyu Lee, Heena R Divecha, Carly Montoya, Andrew E Jaffe, Leonardo Collado Torres, Stephanie Cerceo Page and Keri Martinowich | Summary: The lateral septum (LS), a GABAergic structure located in the basal […]


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Encoding and context-dependent control of reward consumption within the central nucleus of the amygdala

Kavli Affiliate: Patricia Janak | Authors: Kurt M. Fraser, Tabitha H. Kim, Matilde Castro, Céline Drieu, Yasmin Padovan-Hernandez, Bridget Chen, Fiona Pat, David J. Ottenheimer and Patricia H. Janak | Summary: The ability to evaluate and select a preferred option among a variety of available offers is an essential aspect of goal-directed behavior. Dysregulation of […]


Continue.. Encoding and context-dependent control of reward consumption within the central nucleus of the amygdala

Oxysterol-liver X receptor signaling mediates CYFIP1 regulation of cortical neurogenesis

Kavli Affiliate: David Linden | Authors: Daniel C de la Fuente, Claudia Tamburini, Emily Stonelake, William J Griffiths, Jeremy Hall, Michael J Owen, David E. J. Linden, Andrew Pocklington, Yuqin Wang and Meng Li | Summary: Dysregulation in neural progenitor proliferation and neuronal differentiation has been increasingly recognised as a common pathology in neural cells […]


Continue.. Oxysterol-liver X receptor signaling mediates CYFIP1 regulation of cortical neurogenesis

Drebrin Regulates Collateral Axon Branching in Cortical Layer II/III Somatosensory Neurons

Kavli Affiliate: Alex Kolodkin | Authors: Joelle M Dorskind, Sriram Sudarsanam, Randal A Hand, Jakub Ziak, Maame Amoah-Dankwah, Luis Guzman-Clavel, John Lee Soto-Vargas and Alex L Kolodkin | Summary: Proper cortical lamination is essential for cognition, learning, and memory. Within the somatosensory cortex, pyramidal excitatory neurons elaborate axon collateral branches in a laminar-specific manner that […]


Continue.. Drebrin Regulates Collateral Axon Branching in Cortical Layer II/III Somatosensory Neurons

Measuring stimulus-related redundant and synergistic functional connectivity with single cell resolution in auditory cortex

Kavli Affiliate: Patrick Kanold | Authors: Loren Koçillari, Marco Celotto, Nikolas A. Francis, Shoutik Mukherjee, Behtash Babadi, Patrick O. Kanold and Stefano Panzeri | Summary: Measures of functional connectivity have played a central role in advancing our understanding of how information is communicated within the brain. Traditionally, these studies have focused on identifying redundant functional […]


Continue.. Measuring stimulus-related redundant and synergistic functional connectivity with single cell resolution in auditory cortex

Spatially clustered neurons encode vocalization categories in the bat midbrain

Kavli Affiliate: Kishore V. Kuchibhotla, Cynthia F. Moss | Authors: Jennifer Lawlor, Melville Wohlgemuth, Cynthia F Moss and Kishore V Kuchibhotla | Summary: Rapid categorization of vocalizations enables adaptive behavior across species. While categorical perception is thought to arise in the neocortex, humans and other animals could benefit from functional organization of ethologically-relevant sounds at […]


Continue.. Spatially clustered neurons encode vocalization categories in the bat midbrain

Lysinoalanine crosslinking is a conserved post-translational modification in the spirochete flagellar hook

Kavli Affiliate: Michael Miller | Authors: Michael J. Lynch, Maithili Deshpande, Kurni Kyrniyati, Kai Zhang, Milinda James, Michael Miller, Sheng Zhang, Felipe J. Passalia, Elsio A. Wunder, Jr., Nyles W. Charon, Chunhao Li and Brian R Crane | Summary: Spirochete bacteria cause Lyme disease, leptospirosis, syphilis and several other human illnesses. Unlike other bacteria, spirochete […]


Continue.. Lysinoalanine crosslinking is a conserved post-translational modification in the spirochete flagellar hook

Precision-engineered biomimetics: the human fallopian tube

Kavli Affiliate: Denis Wirtz | Authors: Ashleigh J Crawford, André Forjaz, Isha Bhorkar, Triya Roy, David Schell, Vasco Queiroga, Kehan Ren, Donald Kramer, Joanna Bons, Wilson Huang, Gabriella C Russo, Meng-Horng Lee, Birgit Schilling, Pei-Hsun Wu, Ie-Ming Shih, Tian-Li Wang, Ashley Kiemen and Denis Wirtz | Summary: The fallopian tube has an essential role in […]


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Conjunctive vector coding and place coding in hippocampus share a common directional signal

Kavli Affiliate: James Knierim | Authors: Yue-Qing Zhou, Vyash Puliyadi, Xiaojing Chen, Joonhee Leo Lee, Lan-Yuan Zhang and James J Knierim | Summary: Vector coding is becoming increasingly understood as a major mechanism by which neural systems represent an animal’s location in both a global reference frame and a local, item-based reference frame. Landmark vector […]


Continue.. Conjunctive vector coding and place coding in hippocampus share a common directional signal