Kavli Affiliate: Martin Lindquist, Brian Caffo | Authors: Bonnie B. Smith, Yi Zhao, Martin A. Lindquist and Brian Caffo | Summary: Brain functional connectivity analysis of resting-state functional magnetic resonance imaging (fMRI) data is typically performed in a standardized template space assuming consistency of connections across subjects. This can come in the form of one-edge-at-a-time […]
Kavli Affiliate: David Linden | Authors: Jakub Kopal, Kuldeep Kumar, Kimia Shafighi, Karin Saltoun, Claudia Modenato, Clara A. Moreau, Guillaume Huguet, Martineau Jean-Louis, Charles-Olivier Martin, Zohra Saci, Nadine Younis, Elise Douard, Khadije Jizi, Alexis Beauchamp-Chatel, Leila Kushan, Ana I. Silva, Marianne B. M. van den Bree, David E. J. Linden, Michael J. Owen, Jeremy Hall, […]
Kavli Affiliate: Jin Kang | Authors: ChangHui Pak, Rebecca Sebastian, Kang Jin, Narciso Pavon, Ruby Bansal, Andrew Potter, Yoonjae Song, Juliana Babu, Rafael Gabriel, Yubing Sun and Bruce J Aronow | Summary: De novo mutations and copy number deletions in NRXN1 (2p16.3) pose a significant risk for schizophrenia (SCZ). It is unclear how NRXN1 deletions […]
Kavli Affiliate: Patricia Janak | Authors: Kurt M Fraser, Bridget J Chen and Patricia H Janak | Summary: Separable striatal circuits have unique functions in Pavlovian and instrumental behaviors but how these roles relate to performance of sequences of actions with and without associated cues is less clear. Here we tested whether dopamine release and […]
Kavli Affiliate: Reza Shadmehr | Authors: Salomon Zev Muller, Jay S Pi, Paul Hage, Mohammad Amin Fakharian, Ehsan Sedaghat-Nejad and Reza Shadmehr | Summary: The cerebellar cortex performs computations that are critical for control of our actions, and then transmits that information via simple spikes of Purkinje cells (P-cells) to downstream structures. However, because P-cells […]
Kavli Affiliate: Michael Miller, Edward Callaway | Authors: Nathan R Zemke, Ethan J Armand, Wenliang Wang, Seoyeon Lee, Jingtian Zhou, Yang Eric Li, Hanqing Liu, Wei Tian, Joseph R Nery, Rosa G Castanon, Anna Bartlett, Julia K Osteen, Daofeng Li, Xiaoyu Zhuo, Vincent Xu, Michael Miller, Fenna M Krienen, Qiangge Zhang, Naz Taskin, Jonathan Ting, […]
Kavli Affiliate: Donald Geman, Laurent Younes | Authors: Lanlan Ji, An Wang, Shreyash Sonthalia, Daniel Q Naiman, Laurent Younes, Carlo Colantuoni and Donald Geman | Summary: Accurate identification of cell classes across the tissues of living organisms is central in the analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across biomedicine. Such analyses […]
Kavli Affiliate: Keri Martinowich | Authors: Svitlana V Bach, Allison J Bauman, Darya Hosein, Jennifer J Tuscher, Lara Ianov, Kelsey M Greathouse, Benjamin W Henderson, Jeremy H. Herskowitz, Keri Martinowich and Jeremy J Day | Summary: Brain-derived neurotrophic factor (Bdnf) plays a critical role in brain development, dendritic growth, synaptic plasticity, as well as learning […]
Kavli Affiliate: Loyal Goff | Authors: Subhash Kulkarni, Monalee Saha, Jared Slosberg, Alpana Singh, Sushma Nagaraj, Laren S Becker, Chengxiu Zhang, Alicia Bukowski, Zhuolun Wang, Guosheng Liu, Jenna Leser, Mithra Kumar, Shriya Bakhshi, Matthew J Anderson, Mark Lewandoski, Elizabeth Vincent, Loyal Goff and Pankaj Jay Pasricha | Summary: The enteric nervous system (ENS), a collection […]
Kavli Affiliate: Joshua Vogelstein | Authors: Jaewon Chung, Eric W Bridgeford, Michael Powell and Joshua T Vogelstein | Summary: The heritability of human connectomes is crucial for understanding the genetic and environmental factors that influence variations in connectomes, which can provide insights into behavior and disease. However, current approaches to studying connectome heritability assume an […]