Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.

Kavli Affiliate: Seth Blackshaw | Authors: Selin Bekir, Johanna L. Hopf, Theresa Paul, Valerie M. Wiemer, Tyler Santander, Henri E. Skinner, Anna Rada, Friedrich G. Woermann, Thilo Kalbhenn, Barry Giesbrecht, Christian G. Bien, Olaf Sporns, Michael S. Gazzaniga, Lukas J. Volz and Michael B. Miller | Summary: Evolutionary adaptation to diurnal vision in ground squirrels […]


Continue.. Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.

No Disconnection Syndrome after Near-Complete Callosotomy

Kavli Affiliate: Michael Miller | Authors: Selin Bekir, Johanna L. Hopf, Theresa Paul, Valerie M. Wiemer, Tyler Santander, Henri E. Skinner, Anna Rada, Friedrich G. Woermann, Thilo Kalbhenn, Barry Giesbrecht, Christian G. Bien, Olaf Sporns, Michael S. Gazzaniga, Lukas J. Volz and Michael B. Miller | Summary: Sensorimotor processing in the human brain is largely […]


Continue.. No Disconnection Syndrome after Near-Complete Callosotomy

Spatially-resolved molecular sex differences at single cell resolution in the adult human ventromedial and arcuate hypothalamus

Kavli Affiliate: Keri Martinowich | Authors: Bernard Mulvey, Yi Wang, Heena R Divecha, Svitlana V Bach, Kelsey D Montgomery, Sophia Cinquemani, Atharv Chandra, Yufeng Du, Ryan A Miller, Joel E Kleinman, Stephanie Cerceo Page, Thomas M Hyde, Keri Martinowich, Stephanie C Hicks, Kasper D Hansen and Kristen R Maynard | Summary: The hypothalamus contains multiple […]


Continue.. Spatially-resolved molecular sex differences at single cell resolution in the adult human ventromedial and arcuate hypothalamus

Decomposed Linear Dynamical Systems (dLDS) models reveal context-dependent dynamic connectivity in C. elegans

Kavli Affiliate: Adam S. Charles | Authors: Eva Yezerets, Noga Mudrik and Adam Charles | Summary: Mounting empirical evidence indicates that neural “tuning” can be highly variable within an individual across time and especially across individuals. Furthermore, modulatory effects can change the relationship between neurons in the brain as a function of behavioral or other […]


Continue.. Decomposed Linear Dynamical Systems (dLDS) models reveal context-dependent dynamic connectivity in C. elegans

Fast and accessible morphology-free functional fluorescence imaging analysis

Kavli Affiliate: Kishore V. Kuchibhotla and Adam S. Charles | Authors: Alejandro A Estrada Berlanga, Gabrielle Kang, Amanda Kwok, Thomas Broggini, Jennifer Lawlor, Kishore Kuchibhotla, David Kleninfeld, Gal Mishne and Adam Charles | Summary: Optical calcium imaging is a powerful tool for recording neural activity across a wide range of spatial scales, from dendrites and […]


Continue.. Fast and accessible morphology-free functional fluorescence imaging analysis

Vascular endothelial-specific loss of TGF-beta signaling as a model for choroidal neovascularization and central nervous system vascular inflammation

Kavli Affiliate: Jeremy Nathans | Authors: Yanshu Wang, Amir Rattner, Zhongming Li, Philip M Smallwood and Jeremy Nathans | Summary: Cajal-Retzius (CR) cells are glutamatergic neurons that transiently populate the most superficial layer of the isocortex and allocortex during development, serving an essential role during both prenatal and early postnatal brain development. Notably, these cells […]


Continue.. Vascular endothelial-specific loss of TGF-beta signaling as a model for choroidal neovascularization and central nervous system vascular inflammation

CellCover Defines Marker Gene Panels Capturing Developmental Progression in Neocortical Neural Stem Cell Identity

Kavli Affiliate: Laurent Younes and Donald Geman | Authors: Lanlan Ji, An Wang, Shreyash Sonthalia, Seungmae Seo, Daniel Q Naiman, Laurent Younes, Carlo Colantuoni and Donald Geman | Summary: Definition of cell classes across the tissues of living organisms is central in the analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across biomedicine. […]


Continue.. CellCover Defines Marker Gene Panels Capturing Developmental Progression in Neocortical Neural Stem Cell Identity

Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus

Kavli Affiliate: Keri Martinowich | Authors: Alexa F Iannitelli, Leslie Hassanein, Bernard Mulvey, Harris Blankenship, L Cameron Liles, Amanda L Sharpe, Jean-Francois Pare, Arielle Segal, Steven A Sloan, Keri Martinowich, Katharine E McCann, Joseph D Dougherty, Yoland Smith, Michael J Beckstead and David Weinshenker | Summary: The locus coeruleus (LC), the major source of norepinephrine […]


Continue.. Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus

Measuring the functional complexity of nanoscale connectomes: polarity matters

Kavli Affiliate: Carey Priebe and Joshua Vogelstein | Authors: Qingyang Wang, Nadine Randel, Yijie Yin, Cameron Shand, Amy Strange, Michael Winding, Albert Cardona, Marta Zlatic, Joshua Vogelstein and Carey Priebe | Summary: The emerging electron microscopy connectome datasets provides connectivity maps of the brains at single cell resolution, enabling us to estimate various network statistics, […]


Continue.. Measuring the functional complexity of nanoscale connectomes: polarity matters

pH-Sensitive Optical Nanocomposites Using Polymer-Coated Gold Nanorods

Kavli Affiliate: Xingde Li | Authors: Yongping Chen and Xingde Li | Summary: This study investigates the synthesis of pH-responsive, reversible nanocomposites comprising polystyrene sulfonate (PSS)-coated gold nanorods and poly(allylamine hydrochloride) (PAH)-coated gold nanorods, along with their optical properties. We observed a pH-dependent swelling/shrinking of the nanocomposites and a dramatic red-shift (~ 60 nm) of […]


Continue.. pH-Sensitive Optical Nanocomposites Using Polymer-Coated Gold Nanorods