Kavli Affiliate: Dwight Bergles and Loyal Goff | Authors: Dongeun Heo, Anya A. Kim, Björn Neumann, Valerie N. Doze, Yu Kang T Xu, Yevgeniya A. Mironova, Jared Slosberg, Loyal A. Goff, Robin J. M. Franklin and Dwight E Bergles | Summary: Oligodendrocyte progenitor cells (OPCs) are highly dynamic, widely distributed glial cells of the central […]
Kavli Affiliate: Keri Martinowich | Authors: Michael S Totty, Rita Cervera-Juanes, Svitlana V Bach, Lamya Ben Ameur, Madeline R Valentine, Evan Simons, Mckenna D Romac, Hoa Trinh, Krystal Henderson, Ishbel Del Rosario, Madhavi Tippani, Ryan A Miller, Joel E Kleinman, Stephanie Cerceo Page, Arpiar Saunders, Thomas M Hyde, Keri Martinowich, Stephanie C Hicks and Vincent […]
Kavli Affiliate: Cynthia F. Moss | Authors: Nikita M Finger, Keegan E Eveland, Xiaoyan Yin and Cynthia F Moss | Summary: Echolocating bats can navigate complex 3D environments by integrating prior knowledge of spatial layouts and real-time sensory cues. This study demonstrates that inattentional blindness to sensory information undermines successful navigation in Egyptian fruit bats, […]
Kavli Affiliate: Patricia Janak | Authors: Robin Magnard, Yifeng Cheng, Joanna Zhou, Haley Province, Nathalie Thiriet, Patricia H Janak and Youna Vandaele | Summary: Reward-associated cues serve different functions depending on whether they precede or terminate action sequences. Cues that precede action sequences and signal opportunity for reward could serve as GO signals to initiate […]
Kavli Affiliate: Michael Miller | Authors: Emmanuel C Ijezie, Michael J Miller, Celine Hardy, Ava R Jarvis, Timothy Czajka, Lianna D’Brant, Natasha Rugenstein, Adam Waickman, Eain Murphy and David Butler | Summary: INTRODUCTION Herpes simplex virus 1 (HSV-1) infection alters critical markers of Alzheimer’s Disease (AD) in neurons. One key marker of AD is the […]
Kavli Affiliate: Carey Priebe and Joshua Vogelstein | Authors: Qingyang Wang, Albert Cardona, Marta Zlatic, Joshua Vogelstein and Carey Priebe | Summary: Approximately four in five neurons are excitatory. This is true across functional regions and species. Why do we have so many excitatory neurons? Little is known. Here we provide a normative answer to […]
Kavli Affiliate: Jeremias Sulam | Authors: Zhenzhen Wang, Cesar A. Santa-Maria, Aleksander S. Popel and Jeremias Sulam | Summary: The tumor microenvironment is widely recognized for its central role in driving cancer progression and influencing prognostic outcomes. There have been increasing efforts dedicated to characterizing this complex and heterogeneous environment, including developing potential prognostic tools […]
Kavli Affiliate: Timothy Brown and Richard Huganir | Authors: Boaz Mohar, Gabriela Michel, Yi-Zhi Wang, Veronica Hernandez, Jonathan B. Grimm, Jin-Yong Park, Ronak Patel, Morgan Clarke, Timothy A. Brown, Cornelius Bergmann, Kamil K. Gebis, Anika P. Wilen, Bian Liu, Ricard Johnson, Austin Graves, Tatjana Tchumatchenko, Jeffrey N. Savas, Eugenio F. Fornasiero, Richard L. Huganir, Paul […]
Kavli Affiliate: Richard Huganir | Authors: Kevin Chen, Junhua Yang, Bian Liu, Chaohua Jiang, Nicholas Koylass, Zhe Zhang, Shuying Sun, Richard L. Huganir and Zhaozhu Qiu | Summary: Endosomal homeostasis is critical for neuronal function, including the post-synaptic trafficking of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs). Dynamic AMPAR trafficking is a major component of synaptic plasticity, such […]
Kavli Affiliate: Michael Miller | Authors: Juthi Biswas, Dilruba Akter, Michael J Miller, Dennis J Thiele, Eain A. Murphy, Christine O’Connor, Jennifer F Moffat and Gary Chan | Summary: Summary: FDA-approved antivirals against HCMV have several limitations, including only targeting the later stages of the viral replication cycle, adverse side effects, and the emergence of […]