Kavli Affiliate: Michael Shadlen | Authors: Anne Löffler, Ariel Zylberberg, Michael N. Shadlen and Daniel M Wolpert | Summary: Deciding how difficult it is going to be to perform a task allows us to choose between tasks, allocate appropriate resources, and predict future performance. To be useful for planning, difficulty judgments should not require completion […]
Kavli Affiliate: Liam Paninski | Authors: Marcus A Triplett, Marta Gajowa, Hillel Adesnik and Liam Paninski | Summary: Two-photon optogenetics has transformed our ability to probe the structure and function of neural circuits. However, achieving precise optogenetic control of neural ensemble activity has remained fundamentally constrained by the problem of off-target stimulation (OTS): the inadvertent […]
Kavli Affiliate: Vincent Ferrera, Daphna Shohamy, Larry Abbott | Authors: Kenneth Kay, Natalie Biderman, Ramin Khajeh, Manuel Beiran, Christopher J Cueva, Daphna Shohamy, Greg Jensen, Xue-Xin Wei, Vincent P Ferrera and L F Abbott | Summary: Relational cognition — the ability to infer relationships that generalize to novel combinations of objects — is fundamental to […]
Kavli Affiliate: Rui Costa | Authors: Zena K Chatila, Archana Yadav, Jason Mares, Xena E Flowers, Taekyung D Yun, Mamunur Rashid, Ryan Talcoff, Zoe Pelly, Ya Zhang, Philip L De Jager, Andrew F Teich, Rui M Costa, Estela Area Gomez, Gabriela J Martins, Roy N Alcalay, Jean Paul Vonsattel, Vilas Menon, Elizabeth M Bradshaw and […]
Kavli Affiliate: Rui Costa | Authors: Vivek Ravindra Athalye, Preeya Khanna, Suraj Gowda, Amy L Orsborn, Rui M Costa and Jose M Carmena | Summary: It has been proposed that the nervous system has the capacity to generate a wide variety of movements because it re-uses some invariant code. Previous work has identified that dynamics […]
Kavli Affiliate: Sarah Woolley | Authors: Erin Mckenzie Wall and Sarah Cushing Woolley | Summary: Communication governs the formation and maintenance of social relationships. The interpretation of communication signals depends not only on the signal’s content, but also on a receiver’s individual experience. Experiences throughout life may interact to affect behavioral plasticity, such that a […]
Kavli Affiliate: Costa, Rui | Authors: Alice C Mosberger, Leslie J Sibener, Tiffany X Chen, Helio FM Rodrigues, Richard Hormigo, James N Ingram, Vivek R Athalye, Tanya Tabachnik, Daniel M Wolpert, James M Murray and Rui M Costa | Summary: The brain can learn to generate actions, such as reaching to a target, using different […]
Kavli Affiliate: Mark Churchland, Michael Shadlen | Authors: Eric M. Trautmann, Janis K. Hesse, Gabriel M. Stine, Ruobing Xia, Shude Zhu, Daniel J. O’Shea, Bill Karsh, Jennifer Colonell, Frank F. Lanfranchi, Saurabh Vyas, Andrew Zimnik, Natalie A. Steinmann, Daniel A. Wagenaar, Alexandru Andrei, Carolina Mora Lopez, John O’Callaghan, Jan Putzeys, Bogdan C. Raducanu, Marleen Welkenhuysen, […]
Kavli Affiliate: Mark Churchland | Authors: Sean M. Perkins, John P. Cunningham, Qi Wang and Mark M. Churchland | Summary: Decoders for brain-computer interfaces (BCIs) assume constraints on neural activity, chosen to reflect scientific beliefs while yielding tractable computations. We document how low tangling — a typical property of motor-cortex neural trajectories — yields unusual […]
Kavli Affiliate: Rafael Yuste | Authors: Justin Lines and Rafael Yuste | Summary: Neuronal ensembles, defined as groups of coactive neurons, dominate cortical activity and are causally related to perceptual states and behavior. Interestingly, ensembles occur spontaneously in the absence of sensory stimulation. To better understand the function of ensembles in spontaneous activity, we explored […]