Neuromuscular Basis of Drosophila larval escape behavior

Kavli Affiliate: Elizabeth Hillman | Authors: Patricia C. Cooney, Yuhan Huang, Wenze Li, Dulanjana M. Perera, Richard Hormigo, Tanya Tabachnik, Isuru S. Godage, Elizabeth M.C. Hillman, Wesley B. Grueber and Aref A. Zarin | Summary: When threatened by dangerous or harmful stimuli, animals engage in diverse forms of rapid escape behaviors. In Drosophila larvae, one […]


Continue.. Neuromuscular Basis of Drosophila larval escape behavior

Mitochondrial protein FKBP8 captures PDZD8 to form mitochondria-ER contacts

Kavli Affiliate: Franck Polleux | Authors: Koki Nakamura, Saeko Aoyama-Ishiwatari, Takahiro Nagao, Mohammadreza Paaran, Christopher J. Obara, Yui Sakurai-Saito, Jake Johnston, Yudan Du, Shogo Suga, Masafumi Tsuboi, Makoto Nakakido, Kouhei Tsumoto, Yusuke Kishi, Yukiko Gotoh, Chulhwan Kwak, Hyun-Woo Rhee, Jeong Kon Seo, Hidetaka Kosako, Clint Potter, Bridget Carragher, Jennifer Lippincott-Schwartz, Franck Polleux and Yusuke Hirabayashi […]


Continue.. Mitochondrial protein FKBP8 captures PDZD8 to form mitochondria-ER contacts

DARTsort: A modular drift tracking spike sorter for high-density multi-electrode probes

Kavli Affiliate: Liam Paninski | Authors: Julien Boussard, Charlie Windolf, Cole Hurwitz, Hyun Dong Lee, Han Yu, Olivier Winter and Liam Paninski | Summary: With the advent of high-density, multi-electrode probes, there has been a renewed interest in developing robust and scalable algorithms for spike sorting. Current spike sorting approaches, however, struggle to deal with […]


Continue.. DARTsort: A modular drift tracking spike sorter for high-density multi-electrode probes

Sex Differences in Human Music Perception are Negligible

Kavli Affiliate: Sarah Woolley | Authors: Mila Bertolo, Daniel Müllensiefen, Isabelle Peretz, Sarah C. Woolley, Jon T. Sakata and Samuel A. Mehr | Summary: Since Darwin1, researchers have proposed that human musicality evolved in a reproductive context in which males produce music to signal their mate quality to females. Sexually selected traits involve tradeoffs in […]


Continue.. Sex Differences in Human Music Perception are Negligible

Emergent neural dynamics and geometry for generalization in a transitive inference task

Kavli Affiliate: Daphna Shohamy | Authors: Kenneth Kay, Natalie Biderman, Ramin Khajeh, Manuel Beiran, Christopher J Cueva, Daphna Shohamy, Greg Jensen, Xue-Xin Wei, Vincent P Ferrera and L F Abbott | Summary: Relational cognition — the ability to infer relationships that generalize to novel combinations of objects — is fundamental to human and animal intelligence. […]


Continue.. Emergent neural dynamics and geometry for generalization in a transitive inference task

A neural mechanism for discriminating social threat from social safety

Kavli Affiliate: Steven Siegelbaum | Authors: Pegah Kassraian, Shivani K. Bigler, Diana M. Gilly, Neilesh Shrotri and Steven A. Siegelbaum | Summary: The ability to distinguish a threatening from non-threatening conspecific based on past experience is critical for adaptive social behaviors. Although recent progress has been made in identifying the neural circuits that contribute to […]


Continue.. A neural mechanism for discriminating social threat from social safety

Removing direct photocurrent artifacts in optogenetic connectivity mapping data via constrained matrix factorization

Kavli Affiliate: Liam Paninski | Authors: Benjamin Antin, Masato Sadahiro, Marta Gajowa, Marcus A. Triplett, Hillel Adesnik and Liam Paninski | Summary: Monosynaptic connectivity mapping is crucial for building circuit-level models of neural computation. Two-photon optogenetic stimulation, when combined with whole-cell recordings, has the potential to map monosynaptic connectivity at an unprecedented scale. However, optogenetic […]


Continue.. Removing direct photocurrent artifacts in optogenetic connectivity mapping data via constrained matrix factorization

Hue selectivity from recurrent circuitry in Drosophila

Kavli Affiliate: Rudy Behnia | Authors: Matthias P Christenson, Alvaro Sanz Diez, Sarah L Heath, Maia Saavedra-Weisenhaus, Atsuko Adashi, LF Abbott and Rudy Behnia | Summary: A universal principle of sensory perception is the progressive transformation of sensory information from broad non-specific signals to stimulus-selective signals that form the basis of perception. To perceive color, […]


Continue.. Hue selectivity from recurrent circuitry in Drosophila

Single neuron analysis of aging associated changes in learning reveals progressive impairments in transcriptional plasticity

Kavli Affiliate: Robert Hawkins | Authors: Kerriann K Badal, Abhishek Sadhu, Carrie McCracken, Bindu L Raveendra, Sebastian Lozano-Villada, Amol C Shetty, Phillip Gillette, Yibo Zhao, Dustin Stommes, Lynne A Fieber, Michael C Schmale, Anup Mahurkar, Robert D Hawkins and Sathyanarayanan V Puthanveettil | Summary: Molecular mechanisms underlying aging associated impairments in learning and long-term memory […]


Continue.. Single neuron analysis of aging associated changes in learning reveals progressive impairments in transcriptional plasticity

Judging the difficulty of perceptual decisions

Kavli Affiliate: Michael Shadlen | Authors: Anne Löffler, Ariel Zylberberg, Michael N. Shadlen and Daniel M Wolpert | Summary: Deciding how difficult it is going to be to perform a task allows us to choose between tasks, allocate appropriate resources, and predict future performance. To be useful for planning, difficulty judgments should not require completion […]


Continue.. Judging the difficulty of perceptual decisions