Connectome analysis of a cerebellum-like circuit for sensory prediction

Kavli Affiliate: Nathaniel Sawtell | Authors: Krista E Perks, Mariela D Petkova, Salomon Z Muller, Michael Genecin, Adishree Ghatare, Richard Schalek, Yuelong Wu, Michal Januszewski, Viren Jain, Jeff W Lichtman, LF Abbott and Nathaniel B Sawtell | Summary: Transitive inference (TI) is a cognitive process in which decisions are guided by internal representations of abstract […]


Continue.. Connectome analysis of a cerebellum-like circuit for sensory prediction

Learning decouples accuracy and reaction time for rapid decisions in a transitive inference task

Kavli Affiliate: Vincent Ferrera | Authors: Fabian A Munoz Silva, Greg Jensen, Maxwell Shinn, Yelda Alkan, John Murray, Herbert Terrace and Vincent P Ferrera | Summary: Transitive inference (TI) is a cognitive process in which decisions are guided by internal representations of abstract relationships. While the mechanisms underlying transitive learning have been well studied, the […]


Continue.. Learning decouples accuracy and reaction time for rapid decisions in a transitive inference task

Humans share acoustic preferences with other animals

Kavli Affiliate: Sarah Woolley | Authors: Logan S James, Sarah C Woolley, Jon T Sakata, Courtney B Hilton, Michael J Ryan and Samuel A Mehr | Summary: Many animals produce sounds during courtship, and receivers prefer some sounds over others. Shared ancestry and convergent evolution may generate similarities in preference across species and could underlie […]


Continue.. Humans share acoustic preferences with other animals

Exact linear theory of perturbation response in a space- and feature-dependent cortical circuit model

Kavli Affiliate: Kenneth Miller | Authors: Ho Yin Chau, Kenneth D Miller and Agostina Palmigiano | Summary: What are the principles that govern the responses of cortical networks to their inputs and the emergence of these responses from recurrent connectivity? Recent experiments have probed these questions by measuring cortical responses to two-photon optogenetic perturbations of […]


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WITHDRAWN: CEBPB as a potential biomarker for prognosis and immuneinfiltration in clear cell renal cell carcinoma

Kavli Affiliate: Wei Min | Authors: Yaoqiang Ren, Baoping Qiao, Min Wei, Quanfa Tian and Wenke Guo | Summary: The authors have withdrawn this manuscript because [an error in the figures or improper use of them]. Therefore, the authors do not wish this work to be cited as reference for the project. If you have […]


Continue.. WITHDRAWN: CEBPB as a potential biomarker for prognosis and immuneinfiltration in clear cell renal cell carcinoma

Generation of knock-in Cre and FlpO mouse lines for precise targeting of striatal projection neurons and dopaminergic neurons

Kavli Affiliate: Darcy Peterka | Authors: Eddy Albarran, Akira Fushiki, Anders Nelson, David Ng, Corryn Chaimowitz, Laudan Nikoobakht, Tanya Sippy, Darcy S Peterka and Rui M Costa | Summary: The basal ganglia and midbrain dopaminergic systems are critical for motor control, reward processing, and reinforcement learning, with dysfunction in these systems implicated in numerous neurodegenerative […]


Continue.. Generation of knock-in Cre and FlpO mouse lines for precise targeting of striatal projection neurons and dopaminergic neurons

Credit Assignment via Behavioral Timescale Synaptic Plasticity: Theoretical Frameworks

Kavli Affiliate: Rui Costa | Authors: Ian Cone, Claudia Clopath and Rui Ponte Costa | Summary: Behavioral Timescale Synaptic Plasticity (BTSP) is a form of synaptic plasticity in which dendritic Ca2+ plateau potentials in hippocampal pyramidal neurons drive rapid place field formation. Unlike traditional learning rules, BTSP learns correlations on the timescales of seconds and […]


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The selective dynamics of interruptions at short tandem repeats

Kavli Affiliate: Michael Goldberg | Authors: Michael E Goldberg, Harriet Dashnow, Kelley Harris and Aaron R Quinlan | Summary: Short tandem repeats (STRs) are hotspots of genomic instability that mutate at rates orders of magnitude greater than non-repetitive loci due to frequent replication slippage. Expansions at some STR loci cause Mendelian diseases, while variation at […]


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From Morphology to Computation: How Synaptic Organization Shapes Place Fields in CA1 Pyramidal Neurons

Kavli Affiliate: Attila Losonczy | Authors: Simone Tasciotti, Daniel Maxim Iascone, Spyridon Chavlis, Luke Hammond, Yardena Katz, Attila Losonczy, Franck Polleaux and Panayiota Poirazi | Summary: The synaptic mechanisms driving feature selectivity in specific neuron types remains a fundamental and unresolved challenge in neuroscience. In hippocampal CA1 pyramidal neurons (PNs), the development of place selectivity, […]


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Condenzymes: Biomolecular condensates with inherent catalytic activities

Kavli Affiliate: Wei Min | Authors: Michael W Chen, Xiao Guo, Mina Farag, Naixin Qian, Xiaowei Song, Anton Ni, Vicky Liu, Xia Yu, Yuefeng Ma, Leshan Yang, Wen Yu, Matthew King, Joonho Lee, Richard N Zare, Wei Min, Rohit V Pappu and Yifan Dai | Summary: We report the discovery that chemical reactions can be […]


Continue.. Condenzymes: Biomolecular condensates with inherent catalytic activities