Design principles of transcription factors with intrinsically disordered regions

Kavli Affiliate: Ariel Amir | First 5 Authors: Wencheng Ji, Ori Hachmo, Naama Barkai, Ariel Amir, | Summary: Transcription Factors (TFs) are proteins crucial for regulating gene expression. Effective regulation requires the TFs to rapidly bind to the correct target, enabling the cell to respond timely to various stimuli such as nutrient availability or toxin […]


Continue.. Design principles of transcription factors with intrinsically disordered regions

Effect of coat-protein concentration on the self-assembly of bacteriophage MS2 capsids around RNA

Kavli Affiliate: Vinothan N. Manoharan | First 5 Authors: LaNell A. Williams, Andreas Neophytou, Rees F. Garmann, Dwaipayan Chakrabarti, Vinothan N. Manoharan | Summary: Self-assembly is a vital part of the life cycle of certain icosahedral RNA viruses. Furthermore, the assembly process can be harnessed to make icosahedral virus-like particles (VLPs) from coat protein and […]


Continue.. Effect of coat-protein concentration on the self-assembly of bacteriophage MS2 capsids around RNA

Effect of coat-protein concentration on the self-assembly of bacteriophage MS2 capsids around RNA

Kavli Affiliate: Vinothan N. Manoharan | First 5 Authors: LaNell A. Williams, Andreas Neophytou, Rees F. Garmann, Dwaipayan Chakrabarti, Vinothan N. Manoharan | Summary: Self-assembly is a vital part of the life cycle of certain icosahedral RNA viruses. Furthermore, the assembly process can be harnessed to make icosahedral virus-like particles (VLPs) from coat protein and […]


Continue.. Effect of coat-protein concentration on the self-assembly of bacteriophage MS2 capsids around RNA

Precise characterization of nanometer-scale systems using interferometric scattering microscopy and Bayesian analysis

Kavli Affiliate: Vinothan N. Manoharan | First 5 Authors: Xander M. de Wit, Amelia W. Paine, Caroline Martin, Aaron M. Goldfain, Rees F. Garmann | Summary: Interferometric scattering microscopy (iSCAT) can image the dynamics of nanometer-scale systems. The typical approach to analyzing interferometric images involves intensive processing, which discards data and limits the precision of […]


Continue.. Precise characterization of nanometer-scale systems using interferometric scattering microscopy and Bayesian analysis

Precise characterization of nanometer-scale systems using interferometric scattering microscopy and Bayesian analysis

Kavli Affiliate: Vinothan N. Manoharan | First 5 Authors: Xander M. de Wit, Amelia W. Paine, Caroline Martin, Aaron M. Goldfain, Rees F. Garmann | Summary: Interferometric scattering microscopy (iSCAT) can image the dynamics of nanometer-scale systems. The typical approach to analyzing interferometric images involves intensive processing, which discards data and limits the precision of […]


Continue.. Precise characterization of nanometer-scale systems using interferometric scattering microscopy and Bayesian analysis

Precise characterization of nanometer-scale systems using interferometric scattering microscopy and Bayesian analysis

Kavli Affiliate: Vinothan N. Manoharan | First 5 Authors: Xander M. de Wit, Amelia W. Paine, Caroline Martin, Aaron M. Goldfain, Rees F. Garmann | Summary: Interferometric scattering microscopy (iSCAT) can image the dynamics of nanometer-scale systems. The typical approach to analyzing interferometric images involves intensive processing, which discards data and limits the precision of […]


Continue.. Precise characterization of nanometer-scale systems using interferometric scattering microscopy and Bayesian analysis

Precise characterization of nanometer-scale systems using interferometric scattering microscopy and Bayesian analysis

Kavli Affiliate: Vinothan N. Manoharan | First 5 Authors: Xander M. de Wit, Amelia W. Paine, Caroline Martin, Aaron M. Goldfain, Rees F. Garmann | Summary: Interferometric scattering microscopy (iSCAT) can image the dynamics of nanometer-scale systems. The typical approach to analyzing interferometric images involves intensive processing, which discards data and limits the precision of […]


Continue.. Precise characterization of nanometer-scale systems using interferometric scattering microscopy and Bayesian analysis

Zonal flows and reversals of cortically confined active suspensions

Kavli Affiliate: L. Mahadevan | First 5 Authors: J. S. Yodh, F. Giardina, S. Gokhale, L. Mahadevan, | Summary: At sufficiently high concentrations, motile bacteria suspended in fluids exhibit a range of ordered and disordered collective motions. Here we explore the combined effects of confinement, periodicity and curvature induced by the active motion of E. […]


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The effect of scatter of polymer chain length on strength

Kavli Affiliate: Zhigang Suo | First 5 Authors: Manyuan Tao, Shawn Lavoie, Zhigang Suo, Maria K. Cameron, | Summary: A polymer network fractures by breaking covalent bonds, but the experimentally measured strength of the polymer network is orders of magnitude lower than the strength of covalent bonds. We investigate the effect of statistical variation of […]


Continue.. The effect of scatter of polymer chain length on strength

Non-planar snake gaits: from Stigmatic-starts to Sidewinding

Kavli Affiliate: L. Mahadevan | First 5 Authors: N. Charles, R. Chelakkot, M. Gazzola, B. Young, L. Mahadevan | Summary: Of the vast variety of animal gaits, one of the most striking is the non-planar undulating motion of a sidewinder. But non-planar gaits are not limited to sidewinders. Here we report a new non-planar mode […]


Continue.. Non-planar snake gaits: from Stigmatic-starts to Sidewinding