Reward expectation selectively boosts the firing of accumbens D1+ neurons during motivated approach

Kavli Affiliate: Joshua Berke | Authors: Thomas Faust, Ali Mohebi and Joshua D Berke | Summary: The nucleus accumbens (NAc) helps govern motivation to pursue rewards. Two distinct sets of NAc projection neurons – expressing dopamine D1 versus D2 receptors – are thought to promote and suppress motivated behaviors respectively. However, support for this conceptual […]


Continue.. Reward expectation selectively boosts the firing of accumbens D1+ neurons during motivated approach

The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics

Kavli Affiliate: Keri Martinowich | Authors: Lukas M Weber, Heena R Divecha, Matthew N Tran, Sang Ho Kwon, Abby Spangler, Kelsey D Montgomery, Madhavi Tippani, Rahul Bharadwaj, Joel E Kleinman, Stephanie C Page, Thomas M Hyde, Leonardo Collado-Torres, Kristen R Maynard, Keri Martinowich and Stephanie C Hicks | Summary: Norepinephrine (NE) neurons in the locus […]


Continue.. The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics

Costs of resistance limit the effectiveness of cooperation enforcement

Kavli Affiliate: Michael Miller | Authors: Michael E Miller, Susan Sidell and Elizabeth A Ostrowski | Summary: Cooperative groups are susceptible to invasion by cheaters that reap the benefits but fail to pay the costs. Both theory and experimental work have shown that cheating can select for counter-adaptations to resist cheating. But then why is […]


Continue.. Costs of resistance limit the effectiveness of cooperation enforcement

PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression

Kavli Affiliate: Bjoern Schwer | Authors: Christin Schmidt, Sarah Cohen, Brian L. Gudenas, Sarah Husain, Annika Carlson, Samantha Westelman, Linyu Wang, Joanna J. Phillips, Paul A. Northcott, William A. Weiss and Bjoern Schwer | Summary: SNCAIP duplication may promote Group 4 medulloblastoma via induction of PRDM6, a poorly characterized member of the PRDF1 and RIZ1 […]


Continue.. PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression

Laws for Glia Organization Conserved Across Mammals

Kavli Affiliate: Terrence Sejnowski | Authors: Antonio Pinto-Duarte, Katharine Bogue, Terrence J. Sejnowski and Shyam Srinivasan | Summary: The organizational principles of glia remain largely unknown despite their vital role in nervous system function. Previous work has shown that the number of glia per unit volume of neocortex is constant across mammalian species. We hypothesize […]


Continue.. Laws for Glia Organization Conserved Across Mammals

Causal Genetic Loci for a Motivated Behavior Spectrum Harbor Psychiatric Risk Genes

Kavli Affiliate: Su Guo | Authors: Jiale Xu, Romelo Casanave, Apurva S Chitre, Qiyang Wang, Khai-Minh Nguyen, Chiara Blake, Mahendra Wagle, Riyan Cheng, Oksana Polesskaya, Abraham A Palmer and Su Guo | Summary: Behavioral diversity is critical for population fitness. Individual differences in risk-taking are observed across species, but underlying genetic mechanisms and conservation are […]


Continue.. Causal Genetic Loci for a Motivated Behavior Spectrum Harbor Psychiatric Risk Genes

Symmetry-resolved Entanglement Entropy, Spectra & Boundary Conformal Field Theory

Kavli Affiliate: Hirosi Ooguri | First 5 Authors: Yuya Kusuki, Sara Murciano, Hirosi Ooguri, Sridip Pal, | Summary: We perform a comprehensive analysis of the symmetry-resolved (SR) entanglement entropy (EE) for one single interval in the ground state of a $1+1$D conformal field theory (CFT), that is invariant under an arbitrary finite or compact Lie […]


Continue.. Symmetry-resolved Entanglement Entropy, Spectra & Boundary Conformal Field Theory

BASS-XL: X-ray variability properties of unobscured Active Galactic Nuclei

Kavli Affiliate: Claudio Ricci | First 5 Authors: Alessia Tortosa, Claudio Ricci, Patricia ArĂ©valo, Michael J. Koss, Franz E. Bauer | Summary: We investigate the X-ray variability properties of Seyfert1 Galaxies belonging to the BAT AGN Spectroscopic Survey (BASS). The sample includes 151 unobscured (N$_{rm H}<10^{22}$ cm$^{-2}$) AGNs observed with XMM-Newton for a total exposure […]


Continue.. BASS-XL: X-ray variability properties of unobscured Active Galactic Nuclei

Moment of Inertia for Axisymmetric Neutron Stars in the Standard-Model Extension

Kavli Affiliate: Lijing Shao | First 5 Authors: Yiming Dong, Zexin Hu, Rui Xu, Lijing Shao, | Summary: We develop a consistent approach to calculate the moment of inertia (MOI) for axisymmetric neutron stars (NSs) in the Lorentz-violating Standard-Model Extension (SME) framework. To our knowledge, this is the first relativistic MOI calculation for axisymmetric NSs […]


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Probing the Galactic halo with RR Lyrae stars — IV. On the Oosterhoff dichotomy of RR Lyrae stars

Kavli Affiliate: Huawei Zhang | First 5 Authors: Shan Zhang, Gaochao Liu, Yang Huang, Zongfei Lv, Sarah Ann Bird | Summary: We use 3653 (2661 RRab, 992 RRc) RR Lyrae stars (RRLs) with 7D (3D position, 3D velocity, and metallicity) information selected from SDSS, LAMOST, and Gaia EDR3, and divide the sample into two Oosterhoff […]


Continue.. Probing the Galactic halo with RR Lyrae stars — IV. On the Oosterhoff dichotomy of RR Lyrae stars