Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Kavli Affiliate: Denis Wirtz | Authors: Jeanette A.I. Johnson, Genevieve L Stein-O’Brien, Max Booth, Randy Heiland, Furkan Kurtoglu, Daniel Bergman, Elmar Bucher, Atul Deshpande, Andre Forjaz, Michael Getz, Ines Godet, Melissa Lyman, John Metzcar, Jacob Mitchell, Andrew Raddatz, Heber L. Rocha, Jacobo Solorzano, Aneequa Sundus, Yafei Wang, Daniele M. Gilkes, Luciane T. Kagohara, Ashley L. […]


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Probing extreme black-hole outflows on short timescales via high spectral-resolution X-ray imagers

Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Ciro Pinto, James F. Steiner, Arash Bodaghee, Priyanka Chakraborty, Malgosia Sobolewska | Summary: We investigate outflows and the physics of super-Eddington versus sub-Eddington regimes in black hole systems. Our focus is on prospective science using next-generation high-resolution soft X-ray instruments. We highlight the properties of black hole […]


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An Iteratively Decoupled Algorithm for Multiple-Network Poroelastic Model with Applications in Brain Flow Simulations

Kavli Affiliate: Feng Wang | First 5 Authors: Mingchao Cai, Meng Lei, Jingzhi Li, Jiaao Sun, Feng Wang | Summary: In this work, we present an iteratively decoupled algorithm for solving the quasi-static multiple-network poroelastic model. Our approach employs a total-pressure-based formulation with solid displacement, total pressure, and network pressures as primary unknowns. This reformulation […]


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First Detection and Modeling of Spatially Resolved Ly$α$ in TW Hya

Kavli Affiliate: Gregory J. Herczeg | First 5 Authors: Seok-Jun Chang, Nicole Arulanantham, Max Gronke, Gregory J. Herczeg, Edwin A. Bergin | Summary: Lyman-$alpha$ (Ly$alpha$) is the strongest emission line in the accretion-generated UV spectra from T-Tauri stars and, as such, plays a critical role in regulating chemistry within the surrounding protoplanetary disks. Due to […]


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First Results from a Broadband Search for Dark Photon Dark Matter in the $44$ to $52,μ$eV range with a coaxial dish antenna

Kavli Affiliate: Noah A. Kurinsky | First 5 Authors: Stefan Knirck, Gabe Hoshino, Mohamed H. Awida, Gustavo I. Cancelo, Martin Di Federico | Summary: We present first results from a dark photon dark matter search in the mass range from 44 to 52 $mu{rm eV}$ ($10.7 – 12.5,{rm GHz}$) using a room-temperature dish antenna setup […]


Continue.. First Results from a Broadband Search for Dark Photon Dark Matter in the $44$ to $52,μ$eV range with a coaxial dish antenna

Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism

Kavli Affiliate: Edward Chang | Authors: Sunada Khadka, Yu-Hsi Lin, Jeffrey J Ackroyd, Yi-An Chen, Yanghui Sheng, Wubin Qian, Sheng Guo, Yining Chen, Eliot Itzkow Behr, Yasaman Barekatin, Md. Nasir Uddin, Kenisha Arthur, Victoria C Yan, Edward Chang, Anton Poral, Theresa Tran, Wen-Hao Hsu, Surendra Chaurasiya, Dimitra K. Georgiou, John M. Asara, Floris P. Barthel, […]


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Selective Vulnerability of Layer 5a Corticostriatal Neurons in Huntington’s Disease

Kavli Affiliate: Nathaniel Heintz | Authors: Christina Pressl, Kert Mätlik, Laura Kus, Paul Darnell, Ji-Dung Luo, Matthew R Paul, Alison R Weiss, William Liguore, Thomas Carroll, David A Davis, Jodi McBride and Nathaniel Heintz | Summary: The properties of the cell types that are most vulnerable in Huntington’s disease (HD) cortex, the nature of somatic […]


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Cerebellar-driven cortical dynamics enable task acquisition, switching and consolidation

Kavli Affiliate: Costa, Rui | Authors: Joseph Pemberton, Paul Chadderton and Rui Ponte Costa | Summary: Abstract To drive behavior, the cortex must bridge sensory cues with future outcomes. However, the principles by which cortical networks learn such sensory-behavioural transformations remain largely elusive. Here, we posit that the cerebellum assumes a crucial role in driving […]


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A model of marmoset monkey vocal turn-taking

Kavli Affiliate: Cory Miller | Authors: Dori Grijseels, Daniella Fairbank and Cory Miller | Summary: Vocal turn-taking has been described in a diversity of species. Yet a model that captures the various processes underlying this social behavior across species has not been developed. To this end, here we recorded a large and diverse dataset of […]


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Human olfactory neuronal cells through nasal biopsy: molecular characterization and utility in brain science

Kavli Affiliate: Laurent Younes & Donald Geman | Authors: Kun Yang, Koko Ishizuka, Andrew P Lane, Zui Narita, Arisa Hayashida, Yukiko Y Lema, Emma Heffron, Haydn Loudd, Maeve Schumacher, Shin-ichi Kano, Toshifumi Tomoda, Atsushi Kamiya, Minghong Ma, Donald Geman, Laurent Younes and Akira Sawa | Summary: Biopsy is crucial in clinical medicine to obtain tissues […]


Continue.. Human olfactory neuronal cells through nasal biopsy: molecular characterization and utility in brain science