Kavli Affiliate: Robert Edwards | Authors: Michael J. Roach, Sarah Beecroft, Kathie Mihindukulasuriya, Leran Wang, Lais Farias Oliveira Lima, Elizabeth A. Dinsdale, Robert Edwards and Scott Allyn Handley | Summary: The CRISPR-Cas9 system has enabled researchers to precisely modify/edit the sequence of a genome. A typical editing experiment consists of two steps: (i) editing cultured […]
Continue.. Clonally selected lines after CRISPR/Cas editing are not isogenic