klaurent – Page 161 – Kavli Institute Pre-Print Publications

Reduced cholecystokinin-expressing interneuron input contributes to disinhibition of the hippocampal CA2 region in a mouse model of temporal lobe epilepsy

Posted by klaurent November 10, 2022November 21, 2022Columbia

Kavli Affiliate: Steven Siegelbaum | Authors: Alexander C Whitebirch, Anastasia Barnett, Bina Santoro, Helen E Scharfman and Steven A Siegelbaum | Summary: ABSTRACT A significant proportion of temporal lobe epilepsy (TLE) patients experience drug-resistant seizures associated with mesial temporal sclerosis, in which there is extensive cell loss in the hippocampal CA1 and CA3 subfields, with […]

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A comparative atlas of single-cell chromatin accessibility in the human brain

Posted by klaurent November 10, 2022November 21, 2022Hopkins

Kavli Affiliate: Michael Miller | Authors: Yang Eric Li, Sebastian Preissl, Michael Miller, Nicholas D. Johnson, Zihan Wang, Henry Jiao, Chenxu Zhu, Zhaoning Wang, Yang Xie, Olivier Poirin, Colin Kern, Antonio Pinto-Duarte, Wei Tian, Kimberly Siletti, Nora Emerson, Julia Osteen, Jacinta Lucero, Lin Lin, Qian Yang, Sarah Espinoza, Quan Zhu, Nathan Zemke, Anna Marie Yanny, […]

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Triplet Cooper pair splitting in a two-dimensional electron gas

Posted by klaurent November 10, 2022Delft

Kavli Affiliate: Srijit Goswami | First 5 Authors: Qingzhen Wang, Sebastiaan L. D. ten Haaf, Ivan Kulesh, Di Xiao, Candice Thomas | Summary: Cooper pairs occupy the ground state of typical s-wave superconductors and are composed of maximally entangled electrons with opposite spin. In order to study the spin and entanglement properties of these electrons, […]

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Impact of half-wave plate systematics on the measurement of cosmic birefringence from CMB polarization

Posted by klaurent November 10, 2022Tokyo

Kavli Affiliate: Eiichiro Komatsu | First 5 Authors: Marta Monelli, Eiichiro Komatsu, Alexandre E. Adler, Matteo Billi, Paolo Campeti | Summary: Polarization of the cosmic microwave background (CMB) can probe new parity-violating physics such as cosmic birefringence (CB), which requires exquisite control over instrumental systematics. The non-idealities of the half-wave plate (HWP) represent a source […]

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Potassium regulates axon-oligodendrocyte signaling and metabolic coupling in white matter

Posted by klaurent November 9, 2022November 21, 2022Hopkins

Kavli Affiliate: Dwight Bergles | Authors: Zoe J. Looser, Luca Ravotto, Ramona B. Jung, Hauke B. Werner, Torben Ruhwedel, Wiebke Moebius, Dwight E Bergles, L. Felipe Barros, Klaus-Armin Nave, Bruno Weber and Aiman S. Saab | Summary: Abstract The integrity of myelinated axons relies on homeostatic support from oligodendrocytes (OLs), which is essential for brain […]

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Flexible, Scalable, High Channel Count Stereo-Electrode for Recording in the Human Brain

Posted by klaurent November 9, 2022November 21, 2022UCSD / Salk

Kavli Affiliate: Shadi Dayeh, Eric Halgren/p> | Authors: Keundong Lee, Angelique C Paulk, Yun Goo Ro, Daniel R Cleary, Karen J Tonsfeldt, Yoav Kfir, John Pezaris, Youngbin Tchoe, Jihwan Lee, Andrew M Bourhis, Ritwik Vatsyayan, Samantha M Russman, Jimmy C Yang, Amy Baohan, Mark Richardson, Ziv M Williams, Shelley Fried, Ahmed Raslan, Eric Halgren, Sydney […]

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Comparative analysis of single-cell and single-nucleus RNA-sequencing in a rabbit model of retinal detachment-related proliferative vitreoretinopathy.

Posted by klaurent November 8, 2022November 21, 2022Hopkins

Kavli Affiliate: Seth Blackshaw | Authors: Clayton P. Santiago, Megan Y. Gimmen, Yuchen Lu, Minda M. McNally, Leighton H. Duncan, Tyler Creamer, Linda Orzolek, Seth Blackshaw and Mandeep Singh | Summary: Structured Abstract Purpose Proliferative vitreoretinopathy (PVR) is the most common cause of failure of retinal reattachment surgery and the molecular changes leading to this […]

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Structured Joint Decomposition (SJD) identifies conserved molecular dynamics across collections of biologically related multi-omics data matrices

Posted by klaurent November 8, 2022November 21, 2022Hopkins

Kavli Affiliate: Brian Caffo | Authors: Huan Chen, Jinrui Liu, Shreyash Sonthalia, Genevieve Stein-OBrien, Luo Xiao, Brian Caffo and Carlo Colantuoni | Summary: Abstract Motivation It is necessary to develop exploratory tools to learn from the unprecedented volume of high-dimensional multi-omic data currently being produced. We have developed an R package, SJD, which identifies components […]

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Mosaic chromosomal alterations in blood across ancestries via whole-genome sequencing

Posted by klaurent November 8, 2022November 21, 2022UCSD / Salk

Kavli Affiliate: V. S. Ramachandran | Authors: Paul L. Auer, Yasminka A Jakubek, Ying Zhou, Adrienne M Stilp, Jason Bacon, Justin Wong, Braxton Mitchell, Joshua Lewis, Eric Boerwinkle, Ruth J.F. Loos, Michael Preuss, Kathleen Barnes, Nathan Pankratz, Myriam Fornage, Susan Redline, Bruce M. Psaty, Joshua C. Bis, Edwin Silverman, Michael Cho, Jeong Yun, Vasan Ramachandran, […]

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Quick-Look Pipeline Light Curves for 5.7 Million Stars Observed Over the Second Year of TESS’ First Extended Mission

Posted by klaurent November 8, 2022MIT

Kavli Affiliate: Michael Fausnaugh | First 5 Authors: Michelle Kunimoto, Evan Tey, Willie Fong, Katharine Hesse, Avi Shporer | Summary: We present High-Level Science Products (HLSPs) containing light curves from MIT’s Quick-Look Pipeline (QLP) from the second year of TESS’ first Extended Mission (Sectors 40 – 55; 2021 July – 2022 September). In total, 12.2 […]

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