Direct observation of the neural computations underlying a single decision

Kavli Affiliate: Michael Shadlen | Authors: Natalie A Steinemann, Gabriel M Stine, Eric M Trautmann, Ariel Zylberberg, Daniel M Wolpert and Michael N Shadlen | Summary: Neurobiological investigations of perceptual decision-making have furnished the first glimpse of a flexible cognitive process at the level of single neurons (Shadlen and Newsome, 1996; Shadlen and Kiani, 2013). […]


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The Nature of X-Rays from Young Stellar Objects in the Orion Nebula Cluster — A Chandra HETGS Legacy Project

Kavli Affiliate: Norbert S. Schulz | First 5 Authors: Norbert S. Schulz, David P. Huenemoerder, David A. Principe, Marc Gagne, Hans Moritz Günther | Summary: The Orion Nebula Cluster (ONC) is the closest site of very young ($sim$ 1 Myrs) massive star formation. The ONC hosts more than 1600 young and X-ray bright stars with […]


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Bidirectional Regulation of Motor Circuits Using Magnetogenetic Gene Therapy

Kavli Affiliate: Jeffrey M. Friedman | Authors: Santiago R Unda, Roberta Marongiu, Lisa E Pomeranz, Jonathan P Dyke, Edward K Fung, Logan Grosenick, Rick Zirkel, Aldana M Antoniazzi, Sofya Norman, Conor M Liston, Chris B Schaffer, Nozomi Nishimura, Sarah A Stanley, Jeffrey M Friedman and Michael G Kaplitt | Summary: Regulating the activity of discrete […]


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A recurrent network model of planning explains hippocampal replay and human behavior

Kavli Affiliate: Marcelo Mattar | Authors: Kristopher T. Jensen, Guillaume Hennequin and Marcelo G. Mattar | Summary: When interacting with complex environments, humans can rapidly adapt their behavior to changes in task or context. To facilitate this adaptation, we often spend substantial periods of time contemplating possible futures before acting. For such planning to be […]


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The Gravitational Lensing Imprints of DES Y3 Superstructures on the CMB: A Matched Filtering Approach

Kavli Affiliate: Aaron Roodman | First 5 Authors: Umut Demirbozan, Seshadri Nadathur, Ismael Ferrero, Pablo Fosalba, Andras Kovacs | Summary: $ $Low density cosmic voids gravitationally lens the cosmic microwave background (CMB), leaving a negative imprint on the CMB convergence $kappa$. This effect provides insight into the distribution of matter within voids, and can also […]


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Widespread Receptive Field Remapping in Early Visual Cortex

Kavli Affiliate: Anirvan Nandy | Authors: Sachira Denagamage, Mitchell P Morton and Anirvan Nandy | Summary: Our eyes are in constant motion, yet we perceive the visual world as being stable. Predictive remapping of receptive fields is thought to be one of the critical mechanisms for enforcing perceptual stability during eye movements. While receptive field […]


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Magnetogenetic cell activation using endogenous ferritin

Kavli Affiliate: Jeffrey M. Friedman | Authors: Lisa E Pomeranz, Rosemary Li, Xiaofei A Yu, Leah Kelly, Gholamreza Hassanzadeh, Henrik Molina, Daniel Gross, Matthew I Brier, George Vaisey, Putianqi Wang, Maria Jimenez-Gonzalez, Adolfo Garcia-Ocana, Jonathan Dordick, Jeffrey M. Friedman and Sarah A Stanley | Summary: The ability to precisely control the activity of defined cell […]


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Squeezing the quantum noise of a gravitational-wave detector below the standard quantum limit

Kavli Affiliate: Nergis Mavalvala | First 5 Authors: Wenxuan Jia, Victoria Xu, Kevin Kuns, Masayuki Nakano, Lisa Barsotti | Summary: Precision measurements of space and time, like those made by the detectors of the Laser Interferometer Gravitational-wave Observatory (LIGO), are often confronted with fundamental limitations imposed by quantum mechanics. The Heisenberg uncertainty principle dictates that […]


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The representational geometry of emotional states in basolateral amygdala

Kavli Affiliate: Stefano Fusi, Daniel Salzman | Authors: Pia-Kelsey O’Neill, Lorenzo Posani, Jozsef Meszaros, Phebe Warren, Carl E. Schoonover, Andrew J.P. Fink, Stefano Fusi and C. Daniel Salzman | Summary: Sensory stimuli associated with aversive outcomes can cause multiple behavioral responses related to an animal’s evolving emotional state. We employed chemogenetic inactivation and two-photon imaging […]


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Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

Kavli Affiliate: Denis Wirtz | Authors: Devon E Mason, Megan Goeckel, Sebastian L Vega, Pei-Hsun Wu, Dymonn Johnson, Su-Jin Heo, Denis Wirtz, Jason A Burdick, Levi Wood, Brain Y Chow, Amber N Stratman and Joel D Boerckel | Summary: Vascular morphogenesis requires persistent endothelial cell motility that is responsive to diverse and dynamic mechanical stimuli. […]


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