DESI z >~ 5 Quasar Survey. I. A First Sample of 400 New Quasars at z ~ 4.7-6.6

Kavli Affiliate: Risa Wechsler | First 5 Authors: Jinyi Yang, Xiaohui Fan, Ansh Gupta, Adam Myers, Nathalie Palanque-Delabrouille | Summary: We report the first results of a high-redshift ($z$ >~ 5) quasar survey using the Dark Energy Spectroscopic Instrument (DESI). As a DESI secondary target program, this survey is designed to carry out a systematic […]


Continue.. DESI z >~ 5 Quasar Survey. I. A First Sample of 400 New Quasars at z ~ 4.7-6.6

Finemap-MiXeR: A variational Bayesian approach for genetic finemapping

Kavli Affiliate: Anders Dale | Authors: Bayram Cevdet Akdeniz, Oleksandr Frei, Alexey Shadrin, Dmitry Vetrov, Dmitry Kropotov, Anders Dale, Eivind Hovig and Ole Andreassen | Summary: Abstract Discoveries from genome-wide association studies often contain large clusters of highly correlated genetic variants, which makes them hard to interpret. In such cases, finemapping the underlying causal variants […]


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Performant web-based interactive visualization tool for spatially-resolved transcriptomics experiments

Kavli Affiliate: Keri Martinowich | Authors: Chaichontat Sriworarat, Annie B. Nguyen, Nicholas J. Eagles, Leonardo Collado-Torres, Keri Martinowich, Kristen R. Maynard and Stephanie C. Hicks | Summary: High-resolution and multiplexed imaging techniques are giving us an increasingly detailed observation of a biological system. However, sharing, exploring, and customizing the visualization of large multidimensional images can […]


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Three-dimensional genomic mapping of human pancreatic tissue reveals striking multifocality and genetic heterogeneity in precancerous lesions

Kavli Affiliate: Denis Wirtz | Authors: Alicia M Braxton, Ashley L Kiemen, Mia P Grahn, Andre Forjaz, Jaanvi Mahesh Babu, Lily Zheng, Liping Jiang, Haixia Cheng, Qianqian Song, Rebecca Reichel, Sarah Graham, Alexander I Damanakis, Catherine G Fischer, Stephanie Mou, Cameron Metz, Julie Granger, Xiao-Ding Liu, Niklas Bachmann, Cristina Almagro-Perez, Ann Chenyu Jiang, Jeonghyun Yoo, […]


Continue.. Three-dimensional genomic mapping of human pancreatic tissue reveals striking multifocality and genetic heterogeneity in precancerous lesions

Surface acoustic wave resonators on thin film piezoelectric substrates in the quantum regime

Kavli Affiliate: Simon Groblacher | First 5 Authors: Thomas Luschmann, Alexander Jung, Stephan Geprägs, Franz X. Haslbeck, Achim Marx | Summary: Lithium niobate (LNO) is a well established material for surface acoustic wave (SAW) devices including resonators, delay lines and filters. Recently, multi-layer substrates based on LNO thin films have become commercially available. Here, we […]


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Engineered zero-dispersion microcombs using CMOS-ready photonics

Kavli Affiliate: Kerry Vahala | First 5 Authors: Qing-Xin Ji, Warren Jin, Lue Wu, Yan Yu, Zhiquan Yuan | Summary: Normal group velocity dispersion (GVD) microcombs offer high comb line power and high pumping efficiency compared to bright pulse microcombs. The recent demonstration of normal GVD microcombs using CMOS-foundry-produced microresonators is an important step towards […]


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Contribution of protein conformational heterogeneity to NMR lineshapes at cryogenic temperatures

Kavli Affiliate: Ann McDermott | Authors: Xu Yi, Keith Fritzsching, Rivkah Rogawski, Yunyao Xu and Ann E McDermott | Summary: While low temperature NMR holds great promise for the analysis of unstable samples and for sensitizing NMR detection, spectral broadening in frozen protein samples is a common experimental challenge. One hypothesis explaining the additional linewidth […]


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Predicted and Experimental NMR Chemical Shifts at Variable Temperatures: The Effect of Protein Conformational Dynamics

Kavli Affiliate: Ann McDermott | Authors: Xu Yi, Lichirui Zhang, Richard Friesner and Ann E McDermott | Summary: NMR chemical shifts provide a sensitive probe of protein structure and dynamics. Prediction of shifts, and therefore interpretation of shifts, particularly for the frequently measured amidic 15N sites, remains a tall challenge. We demonstrate that protein 15N […]


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Zinc Alters the Supramolecular Organization of Nucleic Acid Complexes with Full-Length TIA1

Kavli Affiliate: Ann McDermott | Authors: Yizhuo Yang, Keith Fritzsching, Sasha He and Ann E McDermott | Summary: T-Cell Intracellular Antigen-1 (TIA1) is a 43 kDa multi-domain RNA-binding protein involved in stress granule formation during eukaryotic stress response, and has been implicated in neurodegenerative diseases including Welander distal myopathy and amyotrophic lateral sclerosis. TIA1 contains […]


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Connecting cooperative transport by ants with the physics of active swimmers

Kavli Affiliate: Ariel Amir | First 5 Authors: Tabea Heckenthaler, Tobias Holder, Ariel Amir, Ofer Feinerman, Ehud Fonio | Summary: Some ant species are known as efficient transporters that can cooperatively carry food items which would be too large for a single ant. Previous studies of cooperative transport focused on the role of individual ants […]


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