Network Biomarkers of Alzheimer’s Disease Risk Derived from Joint Volume and Texture Covariance Patterns in Mouse Models

Posted by dbos Hopkins

Kavli Affiliate: Joshua Vogelstein | Authors: Eric W Bridgeford, Jaewon Chung, Robert J Anderson, Ali Mahzarnia, Jacques A Stout, Hae Sol Moon, Zay Yar Han, Joshua T Vogelstein and Alexandra Badea | Summary: Alzheimer’s disease (AD) lacks effective cures and is typically detected after substantial pathological changes have occurred, making intervention challenging. Early detection and […]


Continue.. Network Biomarkers of Alzheimer’s Disease Risk Derived from Joint Volume and Texture Covariance Patterns in Mouse Models

A Generalist Intracortical Motor Decoder

Posted by dbos UCSF

Kavli Affiliate: Kristofer Bouchard | Authors: Joel Ye, Fabio Rizzoglio, Adam Smoulder, Hongwei Mao, Xuan Ma, Patrick Marino, Raeed H Chowdhury, Dalton D Moore, Gary Blumenthal, Will Hockeimer, Nicolas G. Kunigk, J Patrick Mayo, Aaron P Batista, Steven M Chase, Adam G Rouse, Michael L. Boninger, Charles Greenspon, Andrew B. Schwartz, Nicholas Hatsopoulos, Lee E […]


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Momentum and Matter Matter for Axion Dark Matter Matters on Earth

Posted by dbos Tokyo

Kavli Affiliate: Yevgeny V. Stadnik | First 5 Authors: Abhishek Banerjee, Itay M. Bloch, Quentin Bonnefoy, Sebastian A. R. Ellis, Gilad Perez | Summary: We investigate the implications of matter effects to searches for axion Dark Matter on Earth. The finite momentum of axion Dark Matter is crucial to elucidating the effects of Earth on […]


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Beyond Prompt Content: Enhancing LLM Performance via Content-Format Integrated Prompt Optimization

Posted by dbos UCAS

Kavli Affiliate: Cheng Peng | First 5 Authors: Yuanye Liu, Jiahang Xu, Li Lyna Zhang, Qi Chen, Xuan Feng | Summary: Large Language Models (LLMs) have shown significant capability across various tasks, with their real-world effectiveness often driven by prompt design. While recent research has focused on optimizing prompt content, the role of prompt formatting, […]


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Content-Rich AIGC Video Quality Assessment via Intricate Text Alignment and Motion-Aware Consistency

Posted by dbos Caltech

Kavli Affiliate: Wei Gao | First 5 Authors: Shangkun Sun, Xiaoyu Liang, Bowen Qu, Wei Gao, | Summary: The advent of next-generation video generation models like textit{Sora} poses challenges for AI-generated content (AIGC) video quality assessment (VQA). These models substantially mitigate flickering artifacts prevalent in prior models, enable longer and complex text prompts and generate […]


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Scaling Laws in Patchification: An Image Is Worth 50,176 Tokens And More

Posted by dbos Berkeley

Kavli Affiliate: Feng Wang | First 5 Authors: Feng Wang, Yaodong Yu, Guoyizhe Wei, Wei Shao, Yuyin Zhou | Summary: Since the introduction of Vision Transformer (ViT), patchification has long been regarded as a de facto image tokenization approach for plain visual architectures. By compressing the spatial size of images, this approach can effectively shorten […]


Continue.. Scaling Laws in Patchification: An Image Is Worth 50,176 Tokens And More

Ruling out AGNs as the dominant source of cosmic reionization with JWST

Posted by dbos Peking

Kavli Affiliate: Linhua Jiang | First 5 Authors: Danyang Jiang, Linhua Jiang, Shengxiu Sun, Weiyang Liu, Shuqi Fu | Summary: Cosmic reionization represents the latest phase transition of the intergalactic medium (IGM) in the Universe. It has long been debated whether galaxies or active galactic nuclei (AGNs) are the major source of Lyman continuum (LyC) […]


Continue.. Ruling out AGNs as the dominant source of cosmic reionization with JWST

Ruling out AGNs as the dominant source of cosmic reionization with JWST

Posted by dbos Peking

Kavli Affiliate: Linhua Jiang | First 5 Authors: Danyang Jiang, Linhua Jiang, Shengxiu Sun, Weiyang Liu, Shuqi Fu | Summary: Cosmic reionization represents the latest phase transition of the intergalactic medium (IGM) in the Universe. It has long been debated whether galaxies or active galactic nuclei (AGNs) are the major source of Lyman continuum (LyC) […]


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The conserved N-terminal SANT1-binding domain (SBD) of EZH2 Regulates PRC2 Activity

Posted by dbos Rockefeller

Kavli Affiliate: C. David Allis | Authors: Agata Lemiesz Patriotis, Yadira Soto-Feliciano, Douglas Barrows, Laiba Khan, Marylene Leboeuf, Peder Lund, Matthew R Marunde, Annaelle Djomo, Michael-Christopher Keogh, Thomas Carroll, Benjamin Garcia, Alexey A Soshnev and C. David Allis | Summary: Polycomb group proteins maintain gene expression patterns established during early development, with Polycomb Repressive Complex […]


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Network-aware self-supervised learning enables high-content phenotypic screening for genetic modifiers of neuronal activity dynamics

Posted by dbos UCSF

Kavli Affiliate: Michael Keiser | Authors: Parker Grosjean, Kaivalya Shevade, Cuong Nguyen, Sarah Ancheta, Karl Mader, Ivan Franco, Seok-Jin Heo, Greyson Lewis, Steven Boggess, Angelique De Domenico, Erik Ullian, Shawn Shafer, Adam Litterman, Laralynne Przybyla, Michael J Keiser, Jamie Ifkovits, Adam Yala and Martin Kampmann | Summary: High-throughput phenotypic screening has historically relied on manually […]


Continue.. Network-aware self-supervised learning enables high-content phenotypic screening for genetic modifiers of neuronal activity dynamics