dbos – Page 31 – Kavli Institute Pre-Print Publications

Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson′s disease and Dementia with Lewy bodies

Posted by dbos Yale

Kavli Affiliate: Sreeganga Chandra | Authors: D J Vidyadhara, David Backstrom, Risha Chakraborty, Jiapeng Ruan, Jae-Min Park, Pramod K. Mistry and Sreeganga S. Chandra | Summary: GBA mutations are major risk factors for Parkinson′s disease (PD) and Dementia with Lewy Bodies (DLB), two common α-synucleinopathies associated with cognitive impairment. Here, we investigated the role of […]

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Type 2 diabetes remodels collateral circulation and promotes leukocyte adhesion following ischemic stroke

Posted by dbos October 23, 2024November 4, 2024UCSF

Kavli Affiliate: Michael Stryker | Authors: Yoshimichi Sato, Yuandong Li, Yuya Kato, Atsushi Kanoke, Yujiao Jennifer Sun, Yasuo Nishijima, Ruikang K Wang, Michael Stryker, Hidenori Endo and Jialing Liu | Summary: Type 2 diabetes mellitus (T2DM) is associated with impaired leptomeningeal collateral compensation and poor stroke outcome. Neutrophils tethering and rolling on endothelium after stroke […]

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Endogenous neuronal DNA double-strand breaks are not sufficient to drive brain aging and neurodegeneration

Posted by dbos October 23, 2024November 4, 2024UCSF

Kavli Affiliate: Bjoern Schwer | Authors: Sarah Cohen, Laura Cheradame, Karishma Pratt, Sarah Collins, Ashlie Barillas, Annika Carlson, Vijay Ramani, Gaelle Legube, Saul Villeda, Dyche Mullins and Bjoern Schwer | Summary: Loss of genomic information due to the accumulation of somatic DNA damage has been implicated in aging and neurodegeneration. Somatic mutations in human neurons […]

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Coronagraph-based wavefront sensors for the high Strehl regime

Posted by dbos October 23, 2024November 4, 2024Stanford

Kavli Affiliate: Bruce Macintosh | First 5 Authors: Vincent Chambouleyron, J. Kent Wallace, Rebecca Jensen-Clem, Bruce Macintosh, | Summary: A crucial component of the high-contrast instrumental chain in astronomy is the wavefront sensor (WFS). A key property of this component is its sensitivities, which reflect its ability to efficiently use incoming photons to encode the […]

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Finite-Momentum Pairing State in Unconventional Rashba Systems

Posted by dbos October 23, 2024November 4, 2024Peking

Kavli Affiliate: Ran Wang | First 5 Authors: Ran Wang, Song-Bo Zhang, Ning Hao, , | Summary: In systems with unconventional Rashba bands, we propose that a finite-momentum pairing state can emerge without the need for an external magnetic field. We analyze the phase transition from a zero-momentum Bardeen-Cooper-Schrieffer (BCS) state to a finite-momentum pairing […]

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A measurement of atmospheric circular polarization with POLARBEAR

Posted by dbos October 23, 2024Tokyo

Kavli Affiliate: Tomotake Matsumura | First 5 Authors: Takuro Fujino, Satoru Takakura, Shahed Shayan Arani, Darcy Barron, Carlo Baccigalupi | Summary: At millimeter wavelengths, the atmospheric emission is circularly polarized owing to the Zeeman splitting of molecular oxygen by the Earth’s magnetic field. We report a measurement of the signal in the 150 GHz band […]

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Rare Event Classification with Weighted Logistic Regression for Identifying Repeating Fast Radio Bursts

Posted by dbos October 22, 2024November 4, 2024MIT

Kavli Affiliate: Kiyoshi W. Masui | First 5 Authors: Antonio Herrera-Martin, Radu V. Craiu, Gwendolyn M. Eadie, David C. Stenning, Derek Bingham | Summary: An important task in the study of fast radio bursts (FRBs) remains the automatic classification of repeating and non-repeating sources based on their morphological properties. We propose a statistical model that […]

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ATOMS: ALMA three-millimeter observations of massive star-forming regions — XVIII. On the origin and evolution of dense gas fragments in molecular shells of compact HII regions

Posted by dbos October 22, 2024November 4, 2024Peking

Kavli Affiliate: Ke Wang | First 5 Authors: Siju Zhang, Tie Liu, Ke Wang, Annie Zavagno, Guido Garay | Summary: Fragmentation and evolution for the molecular shells of the compact HII regions are less explored compared to their evolved counterparts. We map nine compact HII regions with a typical diameter of 0.4 pc that are […]

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Dorsal-caudal and ventral hippocampus target different cell populations in the medial frontal cortex in rodents

Posted by dbos October 22, 2024November 4, 2024NTNU

Kavli Affiliate: Menno Witter | Authors: Paola Alemán-Andrade, Menno P. Witter, Ken-Ichiro Tsutsui and Shinya Ohara | Summary: Direct projections from the ventral hippocampus (vHPC) to the medial frontal cortex (MFC) play crucial roles in memory and emotional regulation. Using anterograde transsynaptic tracing and in vitro electrophysiology in mice, we document a previously unexplored pathway […]

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Using the Ca II lines in T Tauri stars to infer the abundance of refractory elements in the innermost disk regions

Posted by dbos October 22, 2024November 4, 2024Peking

Kavli Affiliate: Gregory J. Herczeg | First 5 Authors: Marbely Micolta, Nuria Calvet, Thanawuth Thanathibodee, Gladis Magris C., Carlo F. Manara | Summary: We present a study of the abundance of calcium in the innermost disk of 70 T Tauri stars in the star-forming regions of Chamaeleon I, Lupus and Orion OB1b. We use calcium […]

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