Transcriptomic Profiling of Thyroid Eye Disease Orbital Fat Demonstrates Differences in Adipogenicity and IGF-1R Pathway

Kavli Affiliate: Seth Blackshaw | Authors: Dong Won Kim, Soohyun Kim, Jeong Han, Karan Belday, Emily Li, Nicholas Mahoney, Seth Blackshaw and Fatemeh Rajaii | Summary: Despite recent advances in the treatment of thyroid eye disease (TED), significant gaps remain in our understanding of the underlying molecular mechanisms, particularly concerning the insulin-like growth factor-1 receptor […]


Continue.. Transcriptomic Profiling of Thyroid Eye Disease Orbital Fat Demonstrates Differences in Adipogenicity and IGF-1R Pathway

Transcriptional regulation in the absence of inositol trisphosphate receptor calcium signaling

Kavli Affiliate: Michael W. Young | Authors: Michael Young, David M Booth, David Smith, Marco Tigano, Gyorgy Hajnoczky and Suresh Joseph | Summary: The activation of IP3 receptor (IP3R) Ca2+ channels generates agonist-mediated Ca2+ signals that regulate a wide range of biological processes. It is therefore surprising that CRISPR induced loss of all three IP3R […]


Continue.. Transcriptional regulation in the absence of inositol trisphosphate receptor calcium signaling

A Subcortical Feeding Circuit Linking Interoception to Jaw movement

Kavli Affiliate: Jeffrey M. Friedman and Zachary Knight | Authors: Christin Kosse, Jessica Ivanov, Zachary Knight, Kyle Pellegrino and Jeffrey Friedman | Summary: The brain processes an array of stimuli enabling the selection of an appropriate behavioural response but the neural pathways linking interoceptive inputs to outputs for feeding are poorly understood. Here we delineate […]


Continue.. A Subcortical Feeding Circuit Linking Interoception to Jaw movement

DMesh: A Differentiable Representation for General Meshes

Kavli Affiliate: Yi Zhou | First 5 Authors: Sanghyun Son, Matheus Gadelha, Yang Zhou, Zexiang Xu, Ming C. Lin | Summary: We present a differentiable representation, DMesh, for general 3D triangular meshes. DMesh considers both the geometry and connectivity information of a mesh. In our design, we first get a set of convex tetrahedra that […]


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Stacking X-ray Observations of “Little Red Dots”: Implications for their AGN Properties

Kavli Affiliate: Erin Kara | First 5 Authors: Minghao Yue, Anna-Christina Eilers, Tonima Tasnim Ananna, Christos Panagiotou, Erin Kara | Summary: Recent James Webb Space Telescope (JWST) observations have revealed a population of compact extragalactic objects at $zgtrsim4$ with red near-infrared colors, which have been dubbed as “Little Red Dots" (LRDs). The spectroscopically-selected LRDs exhibit […]


Continue.. Stacking X-ray Observations of “Little Red Dots”: Implications for their AGN Properties

Stacking X-ray Observations of “Little Red Dots”: Implications for their AGN Properties

Kavli Affiliate: Erin Kara | First 5 Authors: Minghao Yue, Anna-Christina Eilers, Tonima Tasnim Ananna, Christos Panagiotou, Erin Kara | Summary: Recent {em James Webb Space Telescope (JWST)} observations have revealed a population of compact extragalactic objects at $zgtrsim4$ with red near-infrared colors, which have been dubbed as “Little Red Dots" (LRDs). The spectroscopically-selected LRDs […]


Continue.. Stacking X-ray Observations of “Little Red Dots”: Implications for their AGN Properties

Stacking X-ray Observations of “Little Red Dots”: Implications for their AGN Properties

Kavli Affiliate: Erin Kara | First 5 Authors: Minghao Yue, Anna-Christina Eilers, Tonima Tasnim Annana, Christos Panagiotou, Erin Kara | Summary: Recent {em James Webb Space Telescope (JWST)} observations have revealed a population of compact extragalactic objects at $zgtrsim4$ with red near-infrared colors, which have been dubbed as “Little Red Dots" (LRDs). The spectroscopically-selected LRDs […]


Continue.. Stacking X-ray Observations of “Little Red Dots”: Implications for their AGN Properties

Effect of disorder on Berry curvature and quantum metric in two-band gapped graphene

Kavli Affiliate: Gang Su | First 5 Authors: Ze Liu, Zhi-Fan Zhang, Zhen-Gang Zhu, Gang Su, | Summary: The geometric properties of parameter space are mostly described by Berry curvature and quantum metric, which are the imaginary and real part of quantum geometric tensor, respectively. In this work, we calculate the dressed Berry curvature and […]


Continue.. Effect of disorder on Berry curvature and quantum metric in two-band gapped graphene

Effect of disorder on Berry curvature and quantum metric in two-band gapped graphene

Kavli Affiliate: Gang Su | First 5 Authors: Ze Liu, Zhi-Fan Zhang, Zhen-Gang Zhu, Gang Su, | Summary: The geometric properties of parameter space are mostly described by Berry curvature and quantum metric, which is the imaginary and real part of quantum geometric tensor, respectively. In this work, we calculate the dressed Berry curvature and […]


Continue.. Effect of disorder on Berry curvature and quantum metric in two-band gapped graphene

Atacama Large Aperture Submillimeter Telescope mbox{(AtLAST)} Science: Probing the Transient and Time-variable Sky

Kavli Affiliate: Claudio Ricci | First 5 Authors: John Orlowski-Scherer, Thomas J. Maccarone, Joe Bright, Tomasz Kaminski, Michael Koss | Summary: The study of transient and variable events, including novae, active galactic nuclei, and black hole binaries, has historically been a fruitful path for elucidating the evolutionary mechanisms of our universe. The study of such […]


Continue.. Atacama Large Aperture Submillimeter Telescope mbox{(AtLAST)} Science: Probing the Transient and Time-variable Sky