Kavli Affiliate: Li Zhao | Authors: Cong Li, Bing-Jun Wang, Junhui Peng, Nicolas Svetec and Li Zhao | Summary: Innate immunity has been dissected in exquisite detail in Drosophila melanogaster, yet how immune systems diversify between species remains largely unknown. Here we compare responses to bacterial infection across five drosophilid species spanning 60 million years of […]
Kavli Affiliate: Claudio Ricci | Summary:We present simultaneous XRISM, XMM-Newton, and NuSTAR observations of ESP 39607, a Seyfert 2 galaxy at $z = 0.201$. XRISM/Resolve reveals two absorption features near 4.7 and 4.9 keV in the observed frame, consistent with redshifted Fe XXV He-$α$/Fe XXVI Ly-$α$ absorption from gas inflowing at $v_rm in simeq 0.16c$. […]
Kavli Affiliate: Feng Long| Summary: Convolutional Neural Networks (CNNs) have undoubtedly revolutionized image data analysis and the field of computer vision. As the cornerstone of CNNs, the convolution operation enables the networks to extract abstract features and uncover hidden relationships in the image data. This paper considers the problem of estimating convolution filters from a […]
Kavli Affiliate: Kenneth Miller | Authors: Ho Yin Chau, Ian Anton Oldenburg, Kenneth D Miller and Agostina Palmigiano | Summary: Optogenetics enables causal manipulation of cortical activity. Perturbation responses can be counterintuitive due to network interactions, making theory essential for predicting them. Existing approaches often rely on linear approximations, which fail for many biologically relevant […]
Kavli Affiliate: Denis Wirtz | Authors: Pei-Hsun Wu, Chongguang Jin, Tiffany Chu, Qiming Zhang and Denis Wirtz | Summary: Preclinical drug evaluation relies heavily on two-dimensional (2D) monolayer assays, which fail to recapitulate the structural and functional complexity of the tumor microenvironment and may therefore misrepresent therapeutic efficacy. Here, we present VITAL (Volumetric Imaging-based Toxicity […]
Kavli Affiliate: Massimo Scanziani and Loren Frank | Authors: Cameron Wilhite, Loren M. Frank and Massimo Scanziani | Summary: Fluid behavior requires temporal coordination across brain systems that orchestrate movement. A clear example is locomotion, in which left and right turns are not only precisely coordinated with the ongoing stepping rhythm but occur at opposite […]
Kavli Affiliate: Massimo Scanziani and Loren Frank | Authors: Cameron Wilhite, Loren M. Frank and Massimo Scanziani | Summary: Motivation Imaging-based spatially resolved transcriptomics (imSRT) technologies provide high-throughput molecular-resolution spatial characterization of genes within cells. Conventional analysis methods to identify cell-types and states in imSRT data rely on gene count matrices derived from tallying the […]
Kavli Affiliate: Menno Veldhorst | Summary:Semiconductor quantum-dot arrays are a compelling platform for scalable quantum technologies, yet their practical operation is hindered by the complexity of tuning large-scale devices. Existing automation tools rely on simplified physical models—such as constant-capacitance approximations and equilibrium Hubbard models—which assume instantaneous relaxation to a steady state. These frameworks fail in […]
Kavli Affiliate: Yasunori Nomura | Summary:A possible gamma-ray excess from the Galactic halo favors dark matter with a mass of several hundred GeV. In previous work, we found that an electroweak scalar doublet is a particularly economical, and nearly uniquely selected, interpretation among simple renormalizable thermal dark-matter models. We point out that its unbroken Z_2 […]
Kavli Affiliate: Luis Ho | Summary:Intermediate-mass black holes (IMBHs) provide a unique regime for studying accretion variability at the low-mass end of the black hole population, yet their intranight optical variability (INOV) remains poorly constrained. We present a systematic investigation of INOV in an optically selected sample of IMBH candidates using high-cadence observations from the […]