August 27, 2026 – Kavli Institute Pre-Print Publications

Fusion-derived phospho-neoepitopes define a prioritized candidate neoantigen repertoire in MASLD-HCC

Posted by dbos August 27, 2026September 9, 2026Rockefeller

Kavli Affiliate: Li Zhao | Authors: Li Na Zhao and Jesper Andersen | Summary: Background The rising burden of metabolic dysfunction-associated steatotic liver disease (MASLD)-associated hepatocellular carcinoma (HCC) underscores the need for innovative therapeutic strategies. Methods We integrated RNA-seq fusion detection, immunopeptidomics, and proteogenomics to systematically prioritize tumor-specific neoantigen candidates arising from gene fusions in MASLD-HCC. Results We […]

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Frequency Synchronization Circuit Model for Analog Vector-Matrix Multiplication in the Frequency Domain

Posted by klaurent August 27, 2026Caltech

Kavli Affiliate: Michael Roukes | Summary:This work introduces a frequency synchronization circuit model for analog vector-matrix multiplication in the frequency domain. The frequency synchronization is implemented by coupling oscillators through all-to-all connections. Each oscillator is implemented using complementary cross-coupled transconductance pairs and RC high-pass filters. In this work, the frequency synchronization is achieved not only […]

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Frequency Synchronization Circuit Model for Analog Vector-Matrix Multiplication in the Frequency Domain

Posted by klaurent August 27, 2026September 9, 2026Caltech

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Dysregulation of the fluid homeostasis system by aging

Posted by dbos August 27, 2026September 9, 2026UCSF

Kavli Affiliate: Zachary Knight | Authors: Heeun Jang, Alexis Behne Sharma, Usan Dan, Jasmine H. Wong, Zachary A. Knight and Jennifer L. Garrison | Summary: Chronic dehydration is a leading cause of morbidity for the elderly, but how aging alters the fluid homeostasis system is not well understood. Here, we used a combination of physiologic, […]

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Resolved Dust in $zapprox1$ Galaxies with JWST/MIRI MRS: Survey Description and First View on PAHs, Mid-IR Atomic Emission, and Warm H$_2$

Posted by klaurent August 27, 2026Tokyo

Kavli Affiliate: John Silverman | Summary:Dust is a key component of galaxies that regulates their thermal balance and, consequently, star formation and the build-up of stellar mass. Polycyclic aromatic hydrocarbons (PAHs) are responsible for reprocessing radiative energy of the galaxies thus tracing dust evolution. Using JWST/MIRI MRS, we present the first resolved view of the […]

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Resolved Dust in $zapprox1$ Galaxies with JWST/MIRI MRS: Survey Description and First View on PAHs, Mid-IR Atomic Emission, and Warm H$_2$

Posted by klaurent August 27, 2026Tokyo

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The Atacama Cosmology Telescope: Constraints on the anisotropic screening and birefringence effects with DR6

Posted by klaurent August 27, 2026September 9, 2026Tokyo

Kavli Affiliate: Toshiya Namikawa | Summary:While we have learned much from recent surveys of the mm-wave sky, many secondary anisotropies of the CMB remain under-explored. We consider two of these here: the anisotropic screening induced by Thomson scattering of CMB photons off free electrons, and cosmic birefringence, the rotation of CMB polarization due to parity-violating […]

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Band’s Geometry Origin of Quantum Spin Transport Phenomena

Posted by klaurent August 27, 2026September 9, 2026Delft

Kavli Affiliate: Mazhar Ali | Summary: We develop a geometric description of spin-dependent transport based on the local geometric structure of electronic bands and the Fermi surfaces. For quasi-two-dimensional systems, we show that hyperbolic regions of constant-energy surfaces generate a geometrical contribution to the Fermi velocity that couples naturally to electron spin and produces a […]

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LightCube: A Parsec-Resolution 3D Model of the Local Far-Ultraviolet Interstellar Radiation Field

Posted by klaurent August 27, 2026September 9, 2026Stanford

Kavli Affiliate: Susan Clark | Summary:We present a three-dimensional model of the local interstellar radiation field (ISRF) in the ultraviolet (UV). Using UV flux measurements from the TD1 catalog and stellar distances from Gaia and Hipparcos, we construct a catalog of stars that we expect to dominate the UV flux in the nearby Galaxy. We […]

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HP6/Umbrea, a rapidly evolving Drosophila HP1-family paralog, is a candidate HP1a-recruited plasticizer of heterochromatin

Posted by dbos August 27, 2026September 9, 2026Rockefeller

Kavli Affiliate: Li Zhao | Authors: UnJin Lee and Li Zhao | Summary: HP6/Umbrea, a rapidly evolving Drosophila (Heterochromatin Protein 1) HP1-family paralog, has well-documented sequence and regulatory evolution but an under-studied molecular function. In this manuscript, we hypothesize that HP6/Umbrea acts as an HP1-recruited plasticizer, providing support for this model using coarse-grained molecular-dynamics simulations of HP1a […]

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