Mammal placental phenotypes are predictable from microRNA repertoires.

Kavli Affiliate: Erich Jarvis | Authors: Jonathan Fenn, Jessica C Edge, Vladimir Ovchinnikov, Olga Amelkina, Melea Sinclair, Tiago H C De Bem, Alessandra Bridi, Irene Malo-Estepa, Angela Gonella-Diaza, Felipe Perecin, Juliano C da Silveira, Guilherme Pugliesi, Flavio Vieira Meirelles, Zenab Butt, Haidee Tinning, Giulio Formenti, Erich Jarvis, Bastian Fromm, James O McInerney, Niamh Forde and […]


Continue.. Mammal placental phenotypes are predictable from microRNA repertoires.

High-fidelity rare structural variant detection with HiFiRE3 reduced representation via restriction enzyme ends

Kavli Affiliate: Bjoern Schwer | Authors: Joseph A Stewart, Jeanmarie Mishler, Samreen Ahmed, Bjoern Schwer, Thomas W. Glover and Thomas E Wilson | Summary: High-fidelity detection of rare structural variants (SVs) remains challenging because library preparation and sequencing techniques generate artifactual junctions that obscure true single-molecule events. Here, we present HiFiRe3, an error-minimized sequencing framework […]


Continue.. High-fidelity rare structural variant detection with HiFiRE3 reduced representation via restriction enzyme ends

Rethinking quantum information in gravity and fields

Kavli Affiliate: Masahito Yamazaki | Summary:This paper presents a curated selection of research questions at the intersection of quantum gravity and quantum information, chosen to highlight issues that we regard as particularly important for researchers in both fields. We organize the discussion into four main themes: the operational characterization of observables, the role of observers, […]


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Numerical polology: towards next-generation model-building for cosmology

Kavli Affiliate: Anthony Lasenby | Summary:The dark sector need not be restricted to simple field content. Indeed, simple bosonic configurations, such as scalar-tensor or dark photon models, contrast with the much richer picture painted by many ultraviolet scenarios. Polology is the study of propagator poles, which correspond to particle states in any given theory. We […]


Continue.. Numerical polology: towards next-generation model-building for cosmology

Numerical polology: towards next-generation model-building for cosmology

Kavli Affiliate: Anthony Lasenby | Summary:The dark sector need not be restricted to simple field content. Indeed, simple bosonic configurations, such as scalar-tensor or dark photon models, contrast with the much richer picture painted by many ultraviolet scenarios. Polology is the study of propagator poles, which correspond to particle states in any given theory. We […]


Continue.. Numerical polology: towards next-generation model-building for cosmology

Unveil the nature of JWST-AGN and Little Red Dots with SKAO continuum surveys

Kavli Affiliate: Roberto Maiolino | Summary:The advent of JWST has revealed a large population of AGN at $z>4$, which are $sim1$ dex more abundant than previously expected, including also the enigmatic population of Little Red Dots (LRDs). Remarkably, the vast majority of JWST-discovered AGN and LRDs are not detected in X-rays, and most of them […]


Continue.. Unveil the nature of JWST-AGN and Little Red Dots with SKAO continuum surveys

The Companions to B and A Stars Snapshot (C-BASS) Survey: I. Discovery of a Young Brown Dwarf Companion to HIP 17453

Kavli Affiliate: Bruce Macintosh | Summary:We report the detection of a new brown dwarf companion to HIP 17453 A, a chemically peculiar A0V star located at a distance of 81 pc. HIP 17453 A was observed with high-resolution adaptive optics imaging using the Near-Infrared Camera 2 on the Keck II telescope as part of the […]


Continue.. The Companions to B and A Stars Snapshot (C-BASS) Survey: I. Discovery of a Young Brown Dwarf Companion to HIP 17453

Little Red Dots as Intermediate Mass, Super-Eddington Engines: Insights from Type IIn Supernovae and The 1837-1856 Great Eruption of $η$ Carinae

Kavli Affiliate: Robert Simcoe | Summary:JWST’s Little Red Dots (LRDs) display a unique constellation of features that do not occur simultaneously in any other class of galaxies or AGN. Here we observe that many of these features find parallels in the 19th century Great Eruption (GE) of $η$ Carinae and a sub-class of supernovae (Type […]


Continue.. Little Red Dots as Intermediate Mass, Super-Eddington Engines: Insights from Type IIn Supernovae and The 1837-1856 Great Eruption of $η$ Carinae

Instrumental-Motor Transfer: The Relative Value of Competing Movement Goals Modulates Implicit Motor Learning

Kavli Affiliate: Vikram Chib | Authors: Naser Al-Fawakhiri, Vikram S. Chib and Samuel D. McDougle | Summary: Multiple learning signals can shape motor output, including reward and punishment (via value-based reinforcement learning) and sensorimotor error (via motor adaptation). However, it is unclear if action values, learned via reinforcement learning, interact with error-based motor learning. Here, […]


Continue.. Instrumental-Motor Transfer: The Relative Value of Competing Movement Goals Modulates Implicit Motor Learning

Dystrophic changes of nigrostriatal axons harboring a Synj1 Parkinson mutation suggest catastrophic failure of endocytic mechanisms

Kavli Affiliate: Pietro De Camilli | Authors: Yumei Wu, Peng Xu, James Moran, C. Shan Xu, Kenneth J. Hayworth, Mian Cao, Lin Shao, D. James Surmeier, Harald F. Hess and Pietro De Camilli | Summary: Synaptojanin 1 is a brain enriched phosphoinositide phosphatase implicated in endocytosis at the synapse. A mutation (R258Q) that selectively impairs […]


Continue.. Dystrophic changes of nigrostriatal axons harboring a Synj1 Parkinson mutation suggest catastrophic failure of endocytic mechanisms