Kavli Affiliate: Anders Dale | Authors: Dat Thanh Nguyen, Alexey A Shadrin, Nadine Parker, Julian Fuhrer, Nam Sy Vo, Anders Dale, Ole Andreassen and Oleksandr Frei | Summary: Despite accumulating evidence that structural variants (SVs) exert disproportionate functional effects, their genome-wide contribution to complex trait heritability has not yet been systematically quantified. Here, we introduce […]
Kavli Affiliate: Shreesh P. Mysore | Authors: Huixin Huang, Shreesh Mysore and Hita Adwanikar | Summary: The ventromedial prefrontal cortex (vmPFC) is known to regulate exploration-avoidance behaviors. Separately, the basolateral amygdala (BLA), which plays a pivotal role in interpreting the emotional valence of external stimuli, is known to send information about aversive cues to the […]
Kavli Affiliate: Roger Nicoll | Authors: tianli dou, junting zhang, yidan hong, xiumin chen and roger nicoll | Summary: Excitatory glutamatergic synapses in the brain are remarkably plastic. Two forms of plasticity have received the most attention: long-term potentiation (LTP) and synaptic homeostasis. While LTP requires the activation of NMDA receptors, synaptic homeostasis does not. […]
Kavli Affiliate: Herman Marshall | Summary:We report the discovery of significant X-ray polarization from the dynamically confirmed black hole X-ray binary (BHXB) GS 1354-64 during its 2025-2026 outburst, obtained with the Imaging X-ray Polarimetry Explorer (IXPE). The observation, obtained shortly after a bright X-ray flare, captures the source in an intermediate state following a stalled […]
Kavli Affiliate: Gordan Krnjaic | Summary:Dark matter direct detection experiments involving electron recoils are beginning to test highly-predictive, thermal-relic milestones for sub-GeV dark matter models. Due to the Lee-Weinberg bound, thermal dark matter candidates in this mass range necessarily require comparably-light mediator particles to achieve a suitably large annihilation cross section. Here we present new […]
Kavli Affiliate: Gordan Krnjaic | Summary:Dark matter direct detection experiments involving electron recoils are beginning to test highly-predictive, thermal-relic milestones for sub-GeV dark matter models. Due to the Lee-Weinberg bound, thermal dark matter candidates in this mass range necessarily require comparably-light mediator particles to achieve a suitably large annihilation cross section. Here we present new […]
Kavli Affiliate: Toshiya Namikawa | Summary:Axions and other very weakly interacting slim particles (WISPs), with masses below 1 GeV, arise naturally in many extensions of the Standard Model of particle physics. In particular, they could offer a new framework to explain the nature of dark matter and may help address a range of puzzling observations […]
Kavli Affiliate: Daniel Mucida | Authors: Roham Parsa, Helder Carvalho de Assis, Tiago B.R. de Castro, Gabriella Lima dos Reis, Arpita Sushil, Harald Hartweger, Angelina Bilate and Daniel Mucida | Summary: Pathogen-specific CD4⁺ T cells undergo dynamic expansion and contraction during infection, ultimately generating memory clones that shape the subsequent immune responses. However, the influence […]
Kavli Affiliate: Giordano Scappucci | Summary:The path to fault-tolerant quantum computing hinges on hardware that scales while remaining compatible with quantum error correction (QEC). Silicon spin qubits are a leading hardware candidate because they combine industrial fabrication compatibility with a nanoscale footprint that could accommodate millions of qubits on a chip. However, their suitability for […]
Kavli Affiliate: Sara Seager | Summary:Liquid is a fundamental requirement for life as we understand it, but whether that liquid has to be water is not known. We propose the hypothesis that ionic liquids (ILs) and deep eutectic solvents (DES) constitute a class of non-aqueous planetary liquids capable of persisting on a wide range of […]