Single-cell profiling of synchronous multi-organ metastasis reveals a systemic CD74+ lipid-associated macrophage niche driving polymetastatic breast cancer

Kavli Affiliate: Robert Edwards | Authors: Jacob Insua-Rodríguez, Pascal Naef, Hannah Savage, Isam Adam, Sung Kook Chun, Axel A Almet, Gautham Prabhakar, Sharon Kwon, Cassandra G Sweet, Sevilla Farah Hennessey, Angela Lincy Prem Antony Samy, Hamad Alshetaiwi, Maren Pein, Sharmila Mallya, Delia F Tifrea, Declan M Edwards, Angela Gomez-Arboledas, Zander Esh, Carina Sandoval, Katrina Taylor […]


Continue.. Single-cell profiling of synchronous multi-organ metastasis reveals a systemic CD74+ lipid-associated macrophage niche driving polymetastatic breast cancer

Structure-guided design of a targeted autoantibody degrader for neurologic disease

Kavli Affiliate: Yifan Cheng | Authors: Marcell Zimanyi, Monica Dayao, Andoni I Asencor, Sravani Kondapavulur, James Asaki, Krista McCutcheon, Cristina Dabaco, Aaron Bodansky, Charles Craik, Samuel Pleasure, Joseph L DeRisi, Yifan Cheng, Michael Wilson and John V Pluvinage | Summary: Despite rapid progress in the diagnosis of autoantibody-mediated neurologic diseases, standard-of-care therapeutic options remain limited […]


Continue.. Structure-guided design of a targeted autoantibody degrader for neurologic disease

A Tunable, Modeless, and Hybridization-free Cross-Kerr Coupler for Miniaturized Superconducting Qubits

Kavli Affiliate: Oskar Painter | Summary:Superconducting quantum circuits typically use capacitive charge-based linear coupling schemes to control interactions between elements such as qubits. While simple and effective, this coupling scheme makes it difficult to satisfy competing circuit design requirements such as maintaining large qubit anharmonicity and coherence along with a high degree of qubit connectivity […]


Continue.. A Tunable, Modeless, and Hybridization-free Cross-Kerr Coupler for Miniaturized Superconducting Qubits

Disorganized Inhibitory Dynamics in Hippocampal area CA1 of 22q11.2 Deletion Mutant Mice

Kavli Affiliate: Attila Losonczy | Authors: Stephanie A Herrlinger, Bovey Rao, Margaret E Conde Paredes, Anna L Tuttman, Haroon Arain, Erdem Varol, Joseph A Gogos and Attila Losonczy | Summary: Individuals with the 22q11.2 deletion syndrome, one of the strongest genetic risk factors for schizophrenia, demonstrate cognitive impairments, including episodic memory dysfunction. Place cell activity […]


Continue.. Disorganized Inhibitory Dynamics in Hippocampal area CA1 of 22q11.2 Deletion Mutant Mice

Revealing Short- and Long-range Li-ion diffusion in Li$_2$MnO$_3$ from finite-temperature dynamical mean field theory

Kavli Affiliate: Kristin Persson | Summary:Li$_2$MnO$_3$ is a key component of Li-excess layered cathodes of the form $(1-x),mathrmLiMO_2 + x,mathrmLi_2MnO_3$ ($M$ = Mn, Ni, Co, dots), yet its role in setting Li-ion transport limitations remains under debate. Here we combine DFT+$U$, finite-temperature DFT+DMFT with a continuous-time quantum Monte Carlo impurity solver, and nudged-elastic-band (NEB) calculations […]


Continue.. Revealing Short- and Long-range Li-ion diffusion in Li$_2$MnO$_3$ from finite-temperature dynamical mean field theory

Revealing Short- and Long-range Li-ion diffusion in Li$_2$MnO$_3$ from finite-temperature dynamical mean field theory

Kavli Affiliate: Kristin Persson | Summary:Li$_2$MnO$_3$ remains a crucial component of the Li-excess layered cathode family, $(1-x),mathrmLiMO_2 + x,mathrmLi_2MnO_3$ ($M$ = Mn, Ni, Co, dots), but its role in limiting Li-ion mobility remains under debate. Here we combine DFT+$U$, finite-temperature DMFT with a continuous-time quantum Monte Carlo impurity solver, and nudged-elastic-band (NEB) calculations to investigate […]


Continue.. Revealing Short- and Long-range Li-ion diffusion in Li$_2$MnO$_3$ from finite-temperature dynamical mean field theory

Alteration of Water Exchange Rates Following Focused Ultrasound-Mediated BBB Opening in the Dorsal Striatum of Non-Human Primates: A Diffusion-Prepared pCASL Study

Kavli Affiliate: Vincent Ferrera | Authors: Dong Liu, Xingfeng Shao, Fabian A Munoz Silva, Soroosh Sanatkhani, Ray Lee, Elisa Konofagou, Danny JJ Wang and Vincent P Ferrera | Summary: This study applied diffusion-prepared pseudo-continuous arterial spin labeling (DP-pCASL) to quantify cerebral blood flow (CBF), arterial transit time (ATT), and blood-brain barrier (BBB) water exchange rate […]


Continue.. Alteration of Water Exchange Rates Following Focused Ultrasound-Mediated BBB Opening in the Dorsal Striatum of Non-Human Primates: A Diffusion-Prepared pCASL Study

Lightcurve Modelling of 2,205 ZTF DR2 Type~Ia Supernovae: Implications for SN Ia Physics and Cosmology

Kavli Affiliate: Kaisey Mandel | Summary:We fit the multi-band light curves of 2,205 Type Ia supernovae (SNe~Ia) from the Zwicky Transient Facility DR2 with a one-zone radioactive decay model with a phenomenological addition to include Fe recombination physics. We find a strong correlation between inferred nickel mass and SALT2 stretch, which our simplified modelling links […]


Continue.. Lightcurve Modelling of 2,205 ZTF DR2 Type~Ia Supernovae: Implications for SN Ia Physics and Cosmology

Lightcurve Modelling of 2,205 ZTF DR2 Type~Ia Supernovae: Implications for SN Ia Physics and Cosmology

Kavli Affiliate: Kaisey Mandel | Summary:We fit the multi-band light curves of 2,205 Type Ia supernovae (SNe~Ia) from the Zwicky Transient Facility DR2 with a one-zone radioactive decay model with a phenomenological addition to include Fe recombination physics. We find a strong correlation between inferred nickel mass and SALT2 stretch, which within our simplified modelling […]


Continue.. Lightcurve Modelling of 2,205 ZTF DR2 Type~Ia Supernovae: Implications for SN Ia Physics and Cosmology

Visualizing the Odd-parity Superconducting Order Parameter and its Quasiparticle Surface Band in UTe2

Kavli Affiliate: J. C. Seamus Davis | Summary:A distinctive identifier of nodal intrinsic topological superconductivity (ITS) would the appearance of an Andreev bound state on crystal surfaces parallel to the nodal axis, in the form of a topological quasiparticle surface band (QSB) appearing only for $T < T_C$. Moreover, theory shows that specific QSB characteristics […]


Continue.. Visualizing the Odd-parity Superconducting Order Parameter and its Quasiparticle Surface Band in UTe2