Robust characterization of selectivity of individual neurons to distinct task-relevant behavioral states using calcium imaging

Posted by dbos Hopkins, This Week: Neuroscience

Kavli Affiliate: Shreesh P. Mysore | Authors: Huixin Huang, Garima Shah, Hita Adwanikar and Shreesh Mysore | Summary: Investigations into the neural basis of behavior have recently employed fluorescence imaging of calcium dynamics in a variety of brain areas to measure neural responses. However, across studies, diverse and seemingly subjective methodological choices have been made […]


Continue.. Robust characterization of selectivity of individual neurons to distinct task-relevant behavioral states using calcium imaging

Mapping cis- and trans-regulatory target genes of human-specific deletions

Posted by dbos This Week: Neuroscience, UCSF

Kavli Affiliate: Alex Pollen | Authors: Tyler Fair, Bryan J Pavlovic, Dani Swope, Octavio E Castillo, Nathan K Schaefer and Alex Aaron Pollen | Summary: Deletion of functional sequence is predicted to represent a fundamental mechanism of molecular evolution. Comparative genetic studies of primates have identified thousands of human-specific deletions (hDels), and the cis-regulatory potential […]


Continue.. Mapping cis- and trans-regulatory target genes of human-specific deletions