Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction

Kavli Affiliate: Ann McDermott | Authors: Cassandra A Chartier, Virgil A Woods, Yunyao Xu, Anne E van Vlimmeren, Marko Jovanovic, Ann E McDermott, Daniel A Keedy and Neel H Shah | Summary: The rapid identification of protein-protein interactions has been significantly enabled by mass spectrometry (MS) proteomics-based methods, including affinity purification-MS, crosslinking-MS, and proximity-labeling proteomics. […]


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UrbanWorld: An Urban World Model for 3D City Generation

Kavli Affiliate: Jiansheng Chen | First 5 Authors: Yu Shang, Jiansheng Chen, Hangyu Fan, Jingtao Ding, Jie Feng | Summary: Cities, as the most fundamental environment of human life, encompass diverse physical elements such as buildings, roads and vegetation with complex interconnection. Crafting realistic, interactive 3D urban environments plays a crucial role in constructing AI […]


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When to Sweat the Small Stuff: identifying the most informative events from ground-based gravitational-wave detectors

Kavli Affiliate: Daniel E. Holz | First 5 Authors: Reed Essick, Daniel E. Holz, , , | Summary: We explore scaling relations for the information carried by individual events, and how that information accumulates in catalogs like those from ground-based gravitational-wave detectors. For a variety of situations, the larger number of quiet/distant signals dominates the […]


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Particle Conversions Beyond the WKB Approximation and Solar-Induced Gravitational Waves from Dark Photon Dark Matter

Kavli Affiliate: Jia Liu | First 5 Authors: Tengyu Ai, Yuxuan He, Jia Liu, Xiaolin Ma, Xiao-Ping Wang | Summary: We investigate the conversion of kinetic mixing dark photon dark matter into gravitational waves within the magnetic field of the Sun. Our study reveals that the WKB approximation is invalid in this scenario. We derive […]


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