Activation of hypoactive parvalbumin-positive fast-spiking interneuron restores dentate inhibition to prevent epileptiform activity in the mouse intrahippocampal kainate model of temporal lobe epilepsy

Posted by dbos Hopkins

Kavli Affiliate: Jin Kang | Authors: Sang-Hun Lee, Young-Jin Kang and Bret N Smith | Summary: Parvalbumin-positive (PV+) GABAergic interneurons in the dentate gyrus provide powerful perisomatic inhibition of dentate granule cells (DGCs) to prevent overexcitation and maintain the stability of dentate gyrus circuits. Most dentate PV+ interneurons survive status epilepticus, but surviving PV+ interneuron […]


Continue.. Activation of hypoactive parvalbumin-positive fast-spiking interneuron restores dentate inhibition to prevent epileptiform activity in the mouse intrahippocampal kainate model of temporal lobe epilepsy

eDIG-CHANGES II: Project Design and Initial Results on NGC 3556

Posted by dbos Peking

Kavli Affiliate: Jing Wang | First 5 Authors: Jiang-Tao Li, Li-Yuan Lu, Zhijie Qu, Robert A. Benjamin, Joel N. Bregman | Summary: The extraplanar diffuse ionized gas (eDIG) represents ionized gases traced by optical/UV lines beyond the stellar extent of galaxies. We herein introduce a novel multi-slit narrow-band spectroscopy method to conduct spatially resolved spectroscopy […]


Continue.. eDIG-CHANGES II: Project Design and Initial Results on NGC 3556

On the relevance of lift force modelling in turbulent wall flows with small inertial particles

Posted by Caltech

Kavli Affiliate: Wei Gao | First 5 Authors: Wei Gao, Pengyu Shi, Matteo Parsani, Pedro Costa, | Summary: In particle-laden turbulent wall flows, lift forces can influence the near-wall turbulence. This has been recently observed in particle-resolved simulations, which, however, are too expensive to be used in upscaled models. Instead, point-particle simulations have been the […]


Continue.. On the relevance of lift force modelling in turbulent wall flows with small inertial particles

On the relevance of lift force modelling in turbulent wall flows with small inertial particles

Posted by Caltech

Kavli Affiliate: Wei Gao | First 5 Authors: Wei Gao, Pengyu Shi, Matteo Parsani, Pedro Costa, | Summary: In particle-laden turbulent wall flows, lift forces can influence the near-wall turbulence. This has been recently observed in particle-resolved simulations, which, however, are too expensive to be used in upscaled models. Instead, point-particle simulations have been the […]


Continue.. On the relevance of lift force modelling in turbulent wall flows with small inertial particles

On the relevance of lift force modelling in turbulent wall flows with small inertial particles

Posted by Caltech

Kavli Affiliate: Wei Gao | First 5 Authors: Wei Gao, Pengyu Shi, Matteo Parsani, Pedro Costa, | Summary: In particle-laden turbulent wall flows, lift forces can influence the near-wall turbulence. This has been recently observed in particle-resolved simulations, which, however, are too expensive to be used in upscaled models. Instead, point-particle simulations have been the […]


Continue.. On the relevance of lift force modelling in turbulent wall flows with small inertial particles

On the relevance of lift force modelling in turbulent wall flows with small inertial particles

Posted by Caltech

Kavli Affiliate: Wei Gao | First 5 Authors: Wei Gao, Pengyu Shi, Matteo Parsani, Pedro Costa, | Summary: In particle-laden turbulent wall flows, lift forces can influence the near-wall turbulence. This has been recently observed in particle-resolved simulations, which, however, are too expensive to be used in upscaled models. Instead, point-particle simulations have been the […]


Continue.. On the relevance of lift force modelling in turbulent wall flows with small inertial particles