Complex spikes perturb movements, revealing the sensorimotor map of Purkinje cells

Posted by klaurent Hopkins

Kavli Affiliate: Reza Shadmehr | Authors: Salomon Zev Muller, Jay S Pi, Paul Hage, Mohammad Amin Fakharian, Ehsan Sedaghat-Nejad and Reza Shadmehr | Summary: The cerebellar cortex performs computations that are critical for control of our actions, and then transmits that information via simple spikes of Purkinje cells (P-cells) to downstream structures. However, because P-cells […]


Continue.. Complex spikes perturb movements, revealing the sensorimotor map of Purkinje cells

Axon initial segment GABA inhibits action potential generation throughout periadolescent development

Posted by klaurent UCSF

Kavli Affiliate: Kevin Bender | Authors: Anna M Lipkin and Kevin J Bender | Summary: Neurons are remarkably polarized structures: dendrites spread and branch to receive synaptic inputs while a single axon extends and transmits action potentials to downstream targets. Neuronal polarity is maintained by the axon initial segment (AIS), a region between the soma […]


Continue.. Axon initial segment GABA inhibits action potential generation throughout periadolescent development