Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer’s Knock-in Mice Require Cellular Prion Protein

Posted by klaurent Yale

Kavli Affiliate: Stephen Strittmatter | Authors: Austin Stoner, Li Fu, LaShae Nicholson, Chao Zheng, Takuya Toyonaga, Joshua Spurrier, Will Laird, Zhengxin Cai and Stephen M. Strittmatter | Summary: Background Cellular prion protein (PrPC) is a high-affinity cell-surface receptor for Amyloid-β oligomers (Aßo). In certain overexpression models of Alzheimer’s Disease (AD), pharmacology and genetics demonstrate its […]


Continue.. Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer’s Knock-in Mice Require Cellular Prion Protein

AGN STORM 2: II. Ultraviolet Observations of Mrk817 with the Cosmic Origins Spectrograph on the Hubble Space Telescope

Posted by klaurent MIT

Kavli Affiliate: Erin A. Kara | First 5 Authors: Y. Homayouni, Gisella De Rosa, Rachel Plesha, Gerard A. Kriss, Aaron J. Barth | Summary: We present reverberation mapping measurements for the prominent ultraviolet broad emission lines of the active galactic nucleus Mrk817 using 165 spectra obtained with the Cosmic Origins Spectrograph on the Hubble Space […]


Continue.. AGN STORM 2: II. Ultraviolet Observations of Mrk817 with the Cosmic Origins Spectrograph on the Hubble Space Telescope

AGN STORM 2: II. Ultraviolet Observations of Mrk817 with the Cosmic Origins Spectrograph on the Hubble Space Telescope

Posted by klaurent MIT

Kavli Affiliate: Erin A. Kara | First 5 Authors: Y. Homayouni, Gisella De Rosa, Rachel Plesha, Gerard A. Kriss, Aaron J. Barth | Summary: We present reverberation mapping measurements for the prominent ultraviolet broad emission lines of the active galactic nucleus Mrk817 using 165 spectra obtained with the Cosmic Origins Spectrograph on the Hubble Space […]


Continue.. AGN STORM 2: II. Ultraviolet Observations of Mrk817 with the Cosmic Origins Spectrograph on the Hubble Space Telescope

Phased nanopore assembly with Shasta and modular graph phasing with GFAse

Posted by klaurent Columbia

Kavli Affiliate: Richard Axel | Authors: Ryan Lorig-Roach, Melissa Meredith, Jean Monlong, Miten Jain, Hugh Olsen, Brandy McNulty, David Porubsky, Tessa G. Montague, Julian Lucas, Chris Condon, Jordan Eizenga, Sissel Juul, Sean McKenzie, Sara Simmonds, Jimin Park, Mobin Asri, Sergey Koren, Evan Eichler, Richard Axel, Bruce Martin, Paolo Carnevali, Karen Miga and Benedict Paten | […]


Continue.. Phased nanopore assembly with Shasta and modular graph phasing with GFAse

A novel fast response and radiation-resistant scintillator detector for beam loss monitor

Posted by klaurent Peking

Kavli Affiliate: Li Xin Li | First 5 Authors: Yuanjing Ji, Zebo Tang, Chen Li, Xin Li, Ming Shao | Summary: At high luminosity areas, beam loss monitor with fast response and high radiation resistance is crucial for accelerator operation. In this article, we report the design and test results of a fast response and […]


Continue.. A novel fast response and radiation-resistant scintillator detector for beam loss monitor

A novel fast response and radiation-resistant scintillator detector for beam loss monitor

Posted by klaurent Peking

Kavli Affiliate: Li Xin Li | First 5 Authors: Yuanjing Ji, Zebo Tang, Chen Li, Xin Li, Ming Shao | Summary: At high luminosity areas, beam loss monitor with fast response and high radiation resistance is crucial for accelerator operation. In this article, we report the design and test results of a fast response and […]


Continue.. A novel fast response and radiation-resistant scintillator detector for beam loss monitor

Sidelobe Modeling and Mitigation for a Three Mirror Anastigmat Cosmic Microwave Background Telescope

Posted by Chicago

Kavli Affiliate: Bradford Benson | First 5 Authors: Ian Gullett, Bradford Benson, Robert Besuner, Richard Bihary, John Carlstrom | Summary: Telescopes measuring cosmic microwave background (CMB) polarization on large angular scales require exquisite control of systematic errors to ensure the fidelity of the cosmological results. In particular, far-sidelobe contamination from wide angle scattering is a […]


Continue.. Sidelobe Modeling and Mitigation for a Three Mirror Anastigmat Cosmic Microwave Background Telescope

Sidelobe Modeling and Mitigation for a Three Mirror Anastigmat Cosmic Microwave Background Telescope

Posted by Chicago

Kavli Affiliate: John Carlstrom | First 5 Authors: Ian Gullett, Bradford Benson, Robert Besuner, Richard Bihary, John Carlstrom | Summary: Telescopes measuring cosmic microwave background (CMB) polarization on large angular scales require exquisite control of systematic errors to ensure the fidelity of the cosmological results. In particular, far-sidelobe contamination from wide angle scattering is a […]


Continue.. Sidelobe Modeling and Mitigation for a Three Mirror Anastigmat Cosmic Microwave Background Telescope

Clumpy wind studies and the non-detection of cyclotron line in OAO 1657-415

Posted by klaurent MIT

Kavli Affiliate: Deepto Chakrabarty | First 5 Authors: Pragati Pradhan, Carlo Ferrigno, Biswajit Paul, Enrico Bozzo, Ileyk El Mellah | Summary: Winds of massive stars are suspected to be inhomogeneous (or clumpy), which biases the measures of their mass loss rates. In High Mass X-ray Binaries (HMXBs), the compact object can be used as an […]


Continue.. Clumpy wind studies and the non-detection of cyclotron line in OAO 1657-415

Clumpy wind studies and the non-detection of cyclotron line in OAO 1657-415

Posted by klaurent MIT

Kavli Affiliate: Deepto Chakrabarty | First 5 Authors: Pragati Pradhan, Carlo Ferrigno, Biswajit Paul, Enrico Bozzo, Ileyk El Mellah | Summary: Winds of massive stars are suspected to be inhomogeneous (or clumpy), which biases the measures of their mass loss rates. In High Mass X-ray Binaries (HMXBs), the compact object can be used as an […]


Continue.. Clumpy wind studies and the non-detection of cyclotron line in OAO 1657-415