Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex

Posted by klaurent UCSF

Kavli Affiliate: Alex Pollen | Authors: Chengyu Deng, Sean Whalen, Marilyn Steyert, Ryan Ziffra, Pawel F Przytycki, Fumitaka Inoue, Daniela Alves Pereira, Davide Capauto, Scott Norton, Flora M. Vaccarino, Alex Aaron Pollen, Tomasz J. Nowakowski, Nadav Ahituv and Katherine S. Pollard | Summary: Nucleotide changes in gene regulatory elements are important determinants of neuronal development […]


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Restructuring of olfactory representations in the fly brain around odor relationships in natural sources

Posted by klaurent UCSD / Salk

Kavli Affiliate: Tatyana Sharpee | Authors: Jie-Yoon Yang, Thomas F O’Connell, Wei-Mien M Hsu, Matthew S Bauer, Kristina V. Dylla, Tatyana O Sharpee and Elizabeth J Hong | Summary: A core challenge of olfactory neuroscience is to understand how neural representations of odor are generated and progressively transformed across different layers of the olfactory circuit […]


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Scrambling and Recovery of Quantum Information in Inhomogeneous Quenches in Two-dimensional Conformal Field Theories

Posted by klaurent UCAS

Kavli Affiliate: Masahiro Nozaki | First 5 Authors: Kanato Goto, Masahiro Nozaki, Shinsei Ryu, Kotaro Tamaoka, Mao Tian Tan | Summary: We study various quantum quench processes induced by the M"obius/sine-square deformation of the Hamiltonian in two-dimensional conformal field theories starting from the thermofield double state in the two copies of the Hilbert space. These […]


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Search for the Epoch of Reionisation with HERA: Upper Limits on the Closure Phase Delay Power Spectrum

Posted by klaurent MIT

Kavli Affiliate: Jacqueline N. Hewitt | First 5 Authors: Pascal M. Keller, Bojan Nikolic, Nithyanandan Thyagarajan, Chris L. Carilli, Gianni Bernardi | Summary: Radio interferometers aiming to measure the power spectrum of the redshifted 21 cm line during the Epoch of Reionisation (EoR) need to achieve an unprecedented dynamic range to separate the weak signal […]


Continue.. Search for the Epoch of Reionisation with HERA: Upper Limits on the Closure Phase Delay Power Spectrum

Search for the Epoch of Reionisation with HERA: Upper Limits on the Closure Phase Delay Power Spectrum

Posted by klaurent MIT

Kavli Affiliate: Jacqueline N. Hewitt | First 5 Authors: Pascal M. Keller, Bojan Nikolic, Nithyanandan Thyagarajan, Chris L. Carilli, Gianni Bernardi | Summary: Radio interferometers aiming to measure the power spectrum of the redshifted 21 cm line during the Epoch of Reionisation (EoR) need to achieve an unprecedented dynamic range to separate the weak signal […]


Continue.. Search for the Epoch of Reionisation with HERA: Upper Limits on the Closure Phase Delay Power Spectrum

A “morphogenetic action” principle for 3D shape formation by the growth of thin sheets

Posted by dbos UCSB

Kavli Affiliate: Boris I. Shraiman | First 5 Authors: Dillon J. Cislo, Anastasios Pavlopoulos, Boris I. Shraiman, , | Summary: How does growth encode form in developing organisms? Many different spatiotemporal growth profiles may sculpt tissues into the same target 3D shapes, but only specific growth patterns are observed in animal and plant development. In […]


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Tuned geometries of hippocampal representations meet the demands of social memory

Posted by klaurent Columbia

Kavli Affiliate: Stefano Fusi | Authors: Lara M. Boyle, Lorenzo Posani, Sarah Irfan, Steven A. Siegelbaum and Stefano Fusi | Summary: Social recognition consists of multiple memory processes, including the detection of familiarity – the ability to rapidly distinguish familiar from novel individuals – and recollection – the effortful recall of where a social episode […]


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Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex

Posted by klaurent Hopkins

Kavli Affiliate: Keri Martinowich | Authors: Louise A. Huuki-Myers, Abby Spangler, Nicholas J. Eagles, Kelsey D. Montgomery, Sang Ho Kwon, Boyi Guo, Melissa Grant-Peters, Heena R. Divecha, Madhavi Tippani, Chaichontat Sriworarat, Annie B. Nguyen, Prashanthi Ravichandran, Matthew N. Tran, Arta Seyedian, PsychENCODE Consortium, Thomas M. Hyde, Joel E. Kleinman, Alexis Battle, Stephanie C. Page, Mina […]


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Vulture: Cloud-enabled scalable mining of microbial reads in public scRNA-seq data

Posted by klaurent UCSF

Kavli Affiliate: Xin Duan | Authors: Junyi Chen, Danqing Yin, Harris Y. H. Wong, Xin Duan, Ken H. O. Yu and Joshua W. K. Ho | Summary: The rapidly growing collection of public single-cell sequencing data have become a valuable resource for molecular, cellular and microbial discovery. Previous studies mostly overlooked detecting pathogens in human […]


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Ultra High Energy Cosmic Ray Source Models: Successes, Challenges and General Predictions

Posted by klaurent Stanford

Kavli Affiliate: Roger Blandford | First 5 Authors: Noemie Globus, Roger Blandford, , , | Summary: Understanding the acceleration of Ultra High Energy Cosmic Rays is one of the great challenges of contemporary astrophysics. In this short review, we summarize the general observational constraints on their composition, spectrum and isotropy which indicate that nuclei heavier […]


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