Kavli Affiliate: Karen Christman | Authors: Holly Sullivan, Yifei Liang, Kendra Worthington, Colin Luo, Nathan C Gianneschi and Karen Christman | Summary: In this paper, we describe block copolymer amphiphiles consisting of a hydrophilic matrix metalloproteinase (MMP) peptide substrate, and a hydrophobic small molecule MMP inhibitor PD166793 for the treatment of acute myocardial infarction. These […]
Continue.. Enzyme-Responsive Nanoparticles for the Targeted Delivery of an MMP Inhibitor to the Heart post Myocardial Infarction