Kavli Affiliate: Jill Leutgeb | Authors: Silvia Viana da Silva, Matthias G Haberl, Kshitij Gaur, Rina Patel, Gautam Narayan, Max Ledakis, Maylin L. Fu, Edward H. Koo, Jill K. Leutgeb and Stefan Leutgeb | Summary: Abstract Deficits in spatial navigation are among the early symptoms in Alzheimer’s disease patients, consistent with the hippocampal formation as […]
Continue.. Localized APP pathology in the hippocampus is sufficient to result in progressive disorganization of the timing of neuronal firing patterns