EMC holdase:CaV1.2/CaVĪ²3 complex and CaV1.2 channel structures reveal CaV assembly and drug binding mechanisms

Posted by klaurent UCSF

Kavli Affiliate: Daniel Minor | Authors: Zhou Chen, Abhisek Mondal, Fayal Abderemane-Ali, Jose Montano, Balyn Zaro and Daniel L Minor, Jr. | Summary: Abstract Voltage-gated ion channels (VGICs) comprise multiple structural units whose assembly is required for function1,2. There is scant structural understanding of how VGIC subunits assemble and whether chaperone proteins are required. High-voltage […]


Continue.. EMC holdase:CaV1.2/CaVĪ²3 complex and CaV1.2 channel structures reveal CaV assembly and drug binding mechanisms

Three-dimensional genome re-wiring in loci with Human Accelerated Regions

Posted by klaurent UCSF

Kavli Affiliate: Alex Pollen | Authors: Kathleen C Keough, Sean Whalen, Fumitaka Inoue, Pawel F Przytycki, Tyler Fair, Chengyu Deng, Marilyn Steyert, Hane Ryu, Kerstin Lindblad-Toh, Elinor Karlsson, Zoonomia Consortium, Tomasz J. Nowakowski, Nadav J. Ahituv, Alex Aaron Pollen and Katherine S Pollard | Summary: Abstract Human Accelerated Regions (HARs) are conserved genomic loci that […]


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A novel $sqrt{19}timessqrt{19}$ superstructure in epitaxially grown 1T-TaTe$_2$

Posted by klaurent Berkeley

Kavli Affiliate: Michael F. Crommie | First 5 Authors: Jinwoong Hwang, Yeongrok Jin, Canxun Zhang, Tiancong Zhu, Kyoo Kim | Summary: The spontaneous formation of electronic orders is a crucial element for understanding complex quantum states and engineering heterostructures in two-dimensional materials. We report a novel $sqrt{19}timessqrt{19}$ charge order in few-layer thick 1T-TaTe$_2$ transition metal […]


Continue.. A novel $sqrt{19}timessqrt{19}$ superstructure in epitaxially grown 1T-TaTe$_2$